(Q33180249)

23 July 2017

1 reference

title

The opioid-receptor-like 1 (ORL-1) as a potential target for new analgesics (English)

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23 July 2017

Barlocco D

1

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23 July 2017

Cignarella G

series ordinal

2

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23 July 2017

Giardina GA

series ordinal

3

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23 July 2017

Toma L

series ordinal

4

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23 July 2017

language of work or name

1 reference

1 March 2000

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European Journal of Medicinal Chemistry

23 July 2017

published in

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23 July 2017

volume

35

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23 July 2017

issue

3

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23 July 2017

page(s)

275-282

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Emerging molecular approaches to pain therapy

23 July 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0223-5234%2800%2900126-4

7 January 2021

ORL1, a novel member of the opioid receptor family. Cloning, functional expression and localization

1 reference

https://api.crossref.org/works/10.1016%2FS0223-5234%2800%2900126-4

7 January 2021

Different domains of the ORL1 and kappa-opioid receptors are involved in recognition of nociceptin and dynorphin A.

1 reference

https://api.crossref.org/works/10.1016%2FS0223-5234%2800%2900126-4

7 January 2021

Orphanin FQ: a neuropeptide that activates an opioidlike G protein-coupled receptor.

1 reference

https://api.crossref.org/works/10.1016%2FS0223-5234%2800%2900126-4

7 January 2021

Isolation and structure of the endogenous agonist of opioid receptor-like ORL1 receptor

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https://api.crossref.org/works/10.1016%2FS0223-5234%2800%2900126-4

7 January 2021

Structure, tissue distribution, and chromosomal localization of the prepronociceptin gene

1 reference

https://api.crossref.org/works/10.1016%2FS0223-5234%2800%2900126-4

7 January 2021

Primary structure and tissue distribution of the orphanin FQ precursor

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7 January 2021

The orphanin FQ system: an emerging target for the management of pain?

1 reference

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7 January 2021

Nocistatin, a peptide that blocks nociceptin action in pain transmission

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7 January 2021

Nociceptin/orphanin FQ and the opioid receptor-like ORL1 receptor

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https://api.crossref.org/works/10.1016%2FS0223-5234%2800%2900126-4

7 January 2021

Nociceptin (orphanin FQ), an endogenous ligand for the QRL1 (opioid-receptor-like1) receptor; modulates responses of trigeminal neurons evoked by excitatory amino acids and somatosensory stimuli

1 reference

https://api.crossref.org/works/10.1016%2FS0223-5234%2800%2900126-4

7 January 2021

Isolation of a novel cDNA encoding a putative membrane receptor with high homology to the cloned mu, delta, and kappa opioid receptors.

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7 January 2021

Functional role and sequence analysis of a lymphocyte orphan opioid receptor

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7 January 2021

Distribution of nociceptin/orphanin FQ receptor transcript in human central nervous system and immune cells.

1 reference

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7 January 2021

Nociceptin activation of the human ORL1 receptor expressed in Chinese hamster ovary cells: functional homology with opioid receptors

1 reference

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7 January 2021

Nociceptin-induced apparent hyperalgesia in mice as a result of the prevention of opioid autoanalgesic mechanisms triggered by the stress of an intracerebroventricular injection

1 reference

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7 January 2021

Naloxone sensitive orphanin FQ-induced analgesia in mice

1 reference

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7 January 2021

Functional antagonism of mu-, delta- and kappa-opioid antinociception by orphanin FQ.

1 reference

https://api.crossref.org/works/10.1016%2FS0223-5234%2800%2900126-4

7 January 2021

Orphanin FQ is a functional anti-opioid peptide.

1 reference

https://api.crossref.org/works/10.1016%2FS0223-5234%2800%2900126-4

7 January 2021

Spinal analgesic activity of orphanin FQ/nociceptin and its fragments

1 reference

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7 January 2021

Identification and characterization of an endogenous ligand for opioid receptor homologue ROR-C: its involvement in allodynic response to innocuous stimulus.

1 reference

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7 January 2021

Characterization of nociceptin hyperalgesia and allodynia in conscious mice

1 reference

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7 January 2021

Anti-hyperalgesic and anti-allodynic effects of intrathecal nociceptin/orphanin FQ in rats after spinal cord injury, peripheral nerve injury and inflammation

1 reference

https://api.crossref.org/works/10.1016%2FS0223-5234%2800%2900126-4

7 January 2021

Antinociceptive and morphine modulatory actions of spinal orphanin FQ.

1 reference

https://api.crossref.org/works/10.1016%2FS0223-5234%2800%2900126-4

7 January 2021

Bidirectional modulatory effect of orphanin FQ on morphine-induced analgesia: antagonism in brain and potentiation in spinal cord of the rat.

1 reference

https://api.crossref.org/works/10.1016%2FS0223-5234%2800%2900126-4

7 January 2021

Effects of intrathecally administered nociceptin, an opioid receptor-like1 (ORL1) receptor agonist, on the thermal hyperalgesia induced by carageenan injection into the rat paw.

1 reference

https://api.crossref.org/works/10.1016%2FS0223-5234%2800%2900126-4

7 January 2021

Peripheral orphanin FQ/nociceptin analgesia in the mouse

1 reference

https://api.crossref.org/works/10.1016%2FS0223-5234%2800%2900126-4

7 January 2021

Presence of opioid receptor-like (ORL1) receptor mRNA splice variants in peripheral sensory and sympathetic neuronal ganglia

1 reference

https://api.crossref.org/works/10.1016%2FS0223-5234%2800%2900126-4

7 January 2021

Nociceptin/orphanin FQ: role in nociceptive information processing

1 reference

https://api.crossref.org/works/10.1016%2FS0223-5234%2800%2900126-4

7 January 2021

Orphanin FQ: receptor binding and analog structure activity relationships in rat brain

1 reference

https://api.crossref.org/works/10.1016%2FS0223-5234%2800%2900126-4

7 January 2021

Structure-activity relationship studies on the novel neuropeptide orphanin FQ.

1 reference

https://api.crossref.org/works/10.1016%2FS0223-5234%2800%2900126-4

7 January 2021

Orphanin FQ/nociceptin modulates glutamate- and kainic acid-induced currents in acutely isolated rat spinal dorsal horn neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0223-5234%2800%2900126-4

7 January 2021

Ligands for kappa-opioid and ORL1 receptors identified from a conformationally constrained peptide combinatorial library

1 reference

https://api.crossref.org/works/10.1016%2FS0223-5234%2800%2900126-4

7 January 2021

Characterization of the high affinity [3H]nociceptin binding site in membrane preparations of rat heart: correlations with the non-opioid dynorphin binding site

1 reference

https://api.crossref.org/works/10.1016%2FS0223-5234%2800%2900126-4

7 January 2021

Antinociceptive analogs of orphanin FQ/nociceptin(1-11)

1 reference

https://api.crossref.org/works/10.1016%2FS0223-5234%2800%2900126-4

7 January 2021

Recognition and activation of the opioid receptor-like ORL 1 receptor by nociceptin, nociceptin analogs and opioids

1 reference

https://api.crossref.org/works/10.1016%2FS0223-5234%2800%2900126-4

7 January 2021

Relationship between binding affinity and functional activity of nociceptin/orphanin FQ.

1 reference

https://api.crossref.org/works/10.1016%2FS0223-5234%2800%2900126-4

7 January 2021

Sensitivity of opioid receptor-like receptor ORL1 for chemical modification on nociceptin, a naturally occurring nociceptive peptide

1 reference

https://api.crossref.org/works/10.1016%2FS0223-5234%2800%2900126-4

7 January 2021

The mouse vas deferens: a pharmacological preparation sensitive to nociceptin

1 reference

https://api.crossref.org/works/10.1016%2FS0223-5234%2800%2900126-4

7 January 2021

Solution conformation of nociceptin.

1 reference

https://api.crossref.org/works/10.1016%2FS0223-5234%2800%2900126-4

7 January 2021

Address and message sequences for the nociceptin receptor: a structure-activity study of nociceptin-(1-13)-peptide amide.

1 reference

https://api.crossref.org/works/10.1016%2FS0223-5234%2800%2900126-4

7 January 2021

Structure−Activity Study of the Nociceptin(1−13)-NH2N-Terminal Tetrapeptide and Discovery of a Nociceptin Receptor Antagonist

1 reference

https://api.crossref.org/works/10.1016%2FS0223-5234%2800%2900126-4

7 January 2021

Nociceptin/orphanin FQ metabolism: role of aminopeptidase and endopeptidase 24.15.

1 reference

https://api.crossref.org/works/10.1016%2FS0223-5234%2800%2900126-4

7 January 2021

Nociceptin receptor binding in mouse forebrain membranes: thermodynamic characteristics and structure activity relationships

1 reference

https://api.crossref.org/works/10.1016%2FS0223-5234%2800%2900126-4

7 January 2021

A new selective antagonist of the nociceptin receptor.

1 reference

https://api.crossref.org/works/10.1016%2FS0223-5234%2800%2900126-4

7 January 2021

[Phe1psi(CH2-NH)Gly2]nociceptin-(1-13)-NH2 is an agonist of the nociceptin (ORL1) receptor.

1 reference

https://api.crossref.org/works/10.1016%2FS0223-5234%2800%2900126-4

7 January 2021

Evidence that [Phe1 psi(CH2-NH)Gly2]nociceptin-(1-13)-NH2, a peripheral ORL-1 receptor antagonist, acts as an agonist in the rat spinal cord

1 reference

https://api.crossref.org/works/10.1016%2FS0223-5234%2800%2900126-4

7 January 2021

Biochemical evidence for orphanin FQ/nociceptin receptor heterogeneity in mouse brain

1 reference

https://api.crossref.org/works/10.1016%2FS0223-5234%2800%2900126-4

7 January 2021

Pharmacological characterization of the nociceptin receptor mediating hyperalgesia in the mouse tail withdrawal assay

1 reference

https://api.crossref.org/works/10.1016%2FS0223-5234%2800%2900126-4

7 January 2021

Automated method for modeling seven-helix transmembrane receptors from experimental data

1 reference

https://api.crossref.org/works/10.1016%2FS0223-5234%2800%2900126-4

7 January 2021

Molecular modelling of the ORL1 receptor and its complex with nociceptin

1 reference

https://api.crossref.org/works/10.1016%2FS0223-5234%2800%2900126-4

7 January 2021

Distinct mechanisms for activation of the opioid receptor-like 1 and kappa-opioid receptors by nociceptin and dynorphin A.

1 reference

https://api.crossref.org/works/10.1016%2FS0223-5234%2800%2900126-4

7 January 2021

8-acenaphthen-1-yl-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one derivatives as orphanin FQ receptor agonists

1 reference

https://api.crossref.org/works/10.1016%2FS0223-5234%2800%2900126-4

7 January 2021

Discovery of the first potent and selective small molecule opioid receptor-like (ORL1) antagonist: 1-[(3R,4R)-1-cyclooctylmethyl-3- hydroxymethyl-4-piperidyl]-3-ethyl-1, 3-dihydro-2H-benzimidazol-2-one (J-113397)

1 reference

https://api.crossref.org/works/10.1016%2FS0223-5234%2800%2900126-4

7 January 2021

10.1016/S0223-5234(00)00126-4

Identifiers

DOI

1 reference

23 July 2017

1 reference