(Q33183063)

English

Targeted down-regulation of MLL-AF9 with antisense oligodeoxyribonucleotide reduces the expression of the HOXA7 and -A10 genes and induces apoptosis in a human leukemia cell line, THP-1.

scientific article

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11681416%20AND%20SRC:MED&resulttype=core&format=json

2 December 2019

Targeted down-regulation of MLL-AF9 with antisense oligodeoxyribonucleotide reduces the expression of the HOXA7 and -A10 genes and induces apoptosis in a human leukemia cell line, THP-1 (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11681416%20AND%20SRC:MED&resulttype=core&format=json

2 December 2019

author name string

H Kawagoe

1

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11681416%20AND%20SRC:MED&resulttype=core&format=json

2 December 2019

R Kawagoe

2

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11681416%20AND%20SRC:MED&resulttype=core&format=json

2 December 2019

K Sano

3

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11681416%20AND%20SRC:MED&resulttype=core&format=json

2 December 2019

publication date

1 November 2001

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11681416%20AND%20SRC:MED&resulttype=core&format=json

2 December 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11681416%20AND%20SRC:MED&resulttype=core&format=json

2 December 2019

15

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11681416%20AND%20SRC:MED&resulttype=core&format=json

2 December 2019

11

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11681416%20AND%20SRC:MED&resulttype=core&format=json

2 December 2019

1743-1749

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11681416%20AND%20SRC:MED&resulttype=core&format=json

2 December 2019

https://scigraph.springernature.com/pub.10.1038/sj.leu.2402262

0 references

Identification of a gene, MLL, that spans the breakpoint in 11q23 translocations associated with human leukemias

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402262

7 January 2021

based on heuristic

inferred from DOI database lookup

The t(4;11) chromosome translocation of human acute leukemias fuses the ALL-1 gene, related to Drosophila trithorax, to the AF-4 gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402262

7 January 2021

based on heuristic

inferred from DOI database lookup

Involvement of a homolog of Drosophila trithorax by 11q23 chromosomal translocations in acute leukemias

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402262

7 January 2021

based on heuristic

inferred from DOI database lookup

Mll rearrangements in haematological malignancies: lessons from clinical and biological studies

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402262

7 January 2021

based on heuristic

inferred from DOI database lookup

11q23 translocations split the "AT-hook" cruciform DNA-binding region and the transcriptional repression domain from the activation domain of the mixed-lineage leukemia (MLL) gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402262

7 January 2021

based on heuristic

inferred from DOI database lookup

Identification and characterization of the ARP1 gene, a target for the human acute leukemia ALL1 gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402262

7 January 2021

based on heuristic

inferred from DOI database lookup

The C-terminal SET domains of ALL-1 and TRITHORAX interact with the INI1 and SNR1 proteins, components of the SWI/SNF complex

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402262

7 January 2021

based on heuristic

inferred from DOI database lookup

The FEL (AF-4) protein donates transcriptional activation sequences to Hrx-Fel fusion proteins in leukemias containing T(4;11)(Q21;Q23) chromosomal translocations

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402262

7 January 2021

based on heuristic

inferred from DOI database lookup

Domains with transcriptional regulatory activity within the ALL1 and AF4 proteins involved in acute leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402262

7 January 2021

based on heuristic

inferred from DOI database lookup

An Mll-AF9 fusion gene made by homologous recombination causes acute leukemia in chimeric mice: a method to create fusion oncogenes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402262

7 January 2021

based on heuristic

inferred from DOI database lookup

Tumorigenesis in mice with a fusion of the leukaemia oncogene Mll and the bacterial lacZ gene.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402262

7 January 2021

based on heuristic

inferred from DOI database lookup

Leucine-zipper dimerization motif encoded by the AF17 gene fused to ALL-1 (MLL) in acute leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402262

7 January 2021

based on heuristic

inferred from DOI database lookup

Altered Hox expression and segmental identity in Mll-mutant mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402262

7 January 2021

based on heuristic

inferred from DOI database lookup

Homeo boxes in the study of development

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402262

7 January 2021

based on heuristic

inferred from DOI database lookup

Murine developmental control genes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402262

7 January 2021

based on heuristic

inferred from DOI database lookup

The murine and Drosophila homeobox gene complexes have common features of organization and expression.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402262

7 January 2021

based on heuristic

inferred from DOI database lookup

Vertebrate homeobox gene nomenclature

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402262

7 January 2021

based on heuristic

inferred from DOI database lookup

The role of HOX homeobox genes in normal and leukemic hematopoiesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402262

7 January 2021

based on heuristic

inferred from DOI database lookup

Differential expression of homeobox genes in functionally distinct CD34+ subpopulations of human bone marrow cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402262

7 January 2021

based on heuristic

inferred from DOI database lookup

Overexpression of HOXA10 in murine hematopoietic cells perturbs both myeloid and lymphoid differentiation and leads to acute myeloid leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402262

7 January 2021

based on heuristic

inferred from DOI database lookup

Hoxa9 transforms primary bone marrow cells through specific collaboration with Meis1a but not Pbx1b

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402262

7 January 2021

based on heuristic

inferred from DOI database lookup

Establishment and characterization of a human acute monocytic leukemia cell line (THP-1)

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402262

7 January 2021

based on heuristic

inferred from DOI database lookup

Expression of HOX genes, HOX cofactors, and MLL in phenotypically and functionally defined subpopulations of leukemic and normal human hematopoietic cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402262

7 January 2021

based on heuristic

inferred from DOI database lookup

Lineage and stage specific expression of HOX 1 genes in the human hematopoietic system

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402262

7 January 2021

based on heuristic

inferred from DOI database lookup

A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin V

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402262

7 January 2021

based on heuristic

inferred from DOI database lookup

The leukemogenic fusion of MLL with ENL creates a novel transcriptional transactivator

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402262

7 January 2021

based on heuristic

inferred from DOI database lookup

Essential roles of retinoic acid signaling in interdigital apoptosis and control of BMP-7 expression in mouse autopods

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402262

7 January 2021

based on heuristic

inferred from DOI database lookup

Cooperative activation of Hoxa and Pbx1-related genes in murine myeloid leukaemias

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402262

7 January 2021

based on heuristic

inferred from DOI database lookup

Reversal of apoptosis by the leukaemia-associated E2A-HLF chimaeric transcription factor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402262

7 January 2021

based on heuristic

inferred from DOI database lookup

The mll-AF9 gene fusion in mice controls myeloproliferation and specifies acute myeloid leukaemogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402262

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q33183063&oldid=1537424336"