(Q33183424)

23 July 2017

title

Imidazoline drugs stabilize lysosomes and inhibit oxidative cytotoxicity in astrocytes (English)

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23 July 2017

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Sang-Hyun Choi

1

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23 July 2017

Dong-Hee Choi

2

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23 July 2017

Jeong-Jin Lee

3

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23 July 2017

Moon-Sung Park

4

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23 July 2017

Boe-Gwun Chun

5

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23 July 2017

publication date

1 March 2002

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Free Radical Biology and Medicine

23 July 2017

published in

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23 July 2017

volume

32

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23 July 2017

issue

5

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23 July 2017

page(s)

394-405

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Aging, energy, and oxidative stress in neurodegenerative diseases.

23 July 2017

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Free radical pathways in CNS injury

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Postischemic administration of idazoxan, an alpha-2 adrenergic receptor antagonist, decreases neuronal damage in the rat brain

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Protection against ischemia-induced neuronal damage by the alpha 2-adrenoceptor antagonist idazoxan: influence of time of administration and possible mechanisms of action.

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Reduction in focal cerebral ischemia by agents acting at imidazole receptors

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7 January 2021

Agmatine treatment is neuroprotective in rodent brain injury models

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7 January 2021

Protection by imidazol(ine) drugs and agmatine of glutamate-induced neurotoxicity in cultured cerebellar granule cells through blockade of NMDA receptor

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7 January 2021

Imidazoline-induced neuroprotective effects result from blockade of NMDA receptor channels in neuronal cultures

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7 January 2021

I1-imidazoline receptors. Definition, characterization, distribution, and transmembrane signaling

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7 January 2021

Tissue-specific localization of mitochondrial imidazoline-guanidinium receptive sites.

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7 January 2021

Expression of non-adrenergic imidazoline sites in rat cerebral cortical astrocytes

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7 January 2021

The elusive family of imidazoline binding sites

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7 January 2021

Cellular injury induced by oxidative stress is mediated through lysosomal damage.

1 reference

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7 January 2021

Lysosomal release of cathepsin D precedes relocation of cytochrome c and loss of mitochondrial transmembrane potential during apoptosis induced by oxidative stress

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7 January 2021

Preparation of separate astroglial and oligodendroglial cell cultures from rat cerebral tissue

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7 January 2021

Commentary. Lysosomotropic agents

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7 January 2021

J-aggregate formation of a carbocyanine as a quantitative fluorescent indicator of membrane potential

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7 January 2021

Intracellular heterogeneity in mitochondrial membrane potentials revealed by a J-aggregate-forming lipophilic cation JC-1.

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7 January 2021

In vivo visualization of oxygen radical-dependent photoemission

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7 January 2021

H2O2-mediated damage to lysosomal membranes of J-774 cells.

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7 January 2021

Insulinoma cells in culture show pronounced sensitivity to alloxan-induced oxidative stress

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7 January 2021

Exposure of cells to nonlethal concentrations of hydrogen peroxide induces degeneration-repair mechanisms involving lysosomal destabilization

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7 January 2021

Photo-oxidative disruption of lysosomal membranes causes apoptosis of cultured human fibroblasts

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7 January 2021

The toxicity to macrophages of oxidized low-density lipoprotein is mediated through lysosomal damage

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7 January 2021

OxLDL-induced macrophage cytotoxicity is mediated by lysosomal rupture and modified by intralysosomal redox-active iron

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7 January 2021

Oxidative stress, growth factor starvation and Fas activation may all cause apoptosis through lysosomal leak

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7 January 2021

Minute oxidative stress is sufficient to induce apoptotic death of NIT-1 insulinoma cells

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7 January 2021

Lethal hydrogen peroxide toxicity involves lysosomal iron-catalyzed reactions with membrane damage

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7 January 2021

Induction of cell death by the lysosomotropic detergent MSDH.

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7 January 2021

Determinants of the apoptotic response to lysosomal photodamage

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7 January 2021

Relocalization of cathepsin D and cytochrome c early in apoptosis revealed by immunoelectron microscopy

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7 January 2021

Protection against oxidant-mediated lysosomal rupture: a new anti-apoptotic activity of Bcl-2?

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7 January 2021

Potential role for cathepsin D in p53-dependent tumor suppression and chemosensitivity.

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7 January 2021

Inhibition of cathepsin D prevents free-radical-induced apoptosis in rat cardiomyocytes

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7 January 2021

Reduction in mitochondrial potential constitutes an early irreversible step of programmed lymphocyte death in vivo.

1 reference

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7 January 2021

Mitochondrial control of apoptosis

1 reference

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7 January 2021

Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c

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7 January 2021

Cytochrome c in the apoptotic and antioxidant cascades

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7 January 2021

The coordinate release of cytochrome c during apoptosis is rapid, complete and kinetically invariant

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7 January 2021

Protection of focal ischemic infarction by rilmenidine in the animal: evidence that interactions with central imidazoline receptors may be neuroprotective

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7 January 2021

Rilmenidine elevates cytosolic free calcium concentration in suspended cerebral astrocytes.

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7 January 2021

Induction of reactive astrocytosis and prevention of motoneuron cell death by the I(2)-imidazoline receptor ligand LSL 60101.

1 reference

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7 January 2021

10.1016/S0891-5849(01)00819-X

Identifiers

DOI

1 reference

23 July 2017

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