(Q33183751)

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Bax expression correlates with cellular drug sensitivity to doxorubicin, cyclophosphamide and chlorambucil but not fludarabine, cladribine or corticosteroids in B cell chronic lymphocytic leukemia

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1 reference

Europe PubMed Central

23 July 2017

Bax expression correlates with cellular drug sensitivity to doxorubicin, cyclophosphamide and chlorambucil but not fludarabine, cladribine or corticosteroids in B cell chronic lymphocytic leukemia (English)

1 reference

Europe PubMed Central

23 July 2017

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chronic lymphocytic leukemia

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author name string

Bosanquet AG

1

1 reference

Europe PubMed Central

23 July 2017

Sturm I

2

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Europe PubMed Central

23 July 2017

Wieder T

3

1 reference

Europe PubMed Central

23 July 2017

Essmann F

4

1 reference

Europe PubMed Central

23 July 2017

Bosanquet MI

5

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Europe PubMed Central

23 July 2017

Head DJ

6

1 reference

Europe PubMed Central

23 July 2017

Dörken B

7

1 reference

Europe PubMed Central

23 July 2017

Daniel PT

8

1 reference

Europe PubMed Central

23 July 2017

publication date

1 June 2002

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Europe PubMed Central

23 July 2017

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Europe PubMed Central

23 July 2017

16

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Europe PubMed Central

23 July 2017

6

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Europe PubMed Central

23 July 2017

1035-1044

1 reference

Europe PubMed Central

23 July 2017

https://scigraph.springernature.com/pub.10.1038/sj.leu.2402539

0 references

Dissecting the pathways to death

1 reference

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Chemosensitivity of B cell chronic lymphocytic leukemia and correlated expression of proteins regulating apoptosis, cell cycle and DNA repair.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402539

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Chlorambucil resistance in B-cell chronic lymphocytic leukaemia is mediated through failed Bax induction and selection of high Bcl-2-expressing subclones

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402539

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Impaired BAX protein expression in breast cancer: mutational analysis of the BAX and the p53 gene

1 reference

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7 January 2021

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Analysis of the p53/BAX pathway in colorectal cancer: low BAX is a negative prognostic factor in patients with resected liver metastases

1 reference

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7 January 2021

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Overexpression of the death-promoting gene bax-alpha which is downregulated in breast cancer restores sensitivity to different apoptotic stimuli and reduces tumor growth in SCID mice

1 reference

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Induction of the death-promoting gene bax-alpha sensitizes cultured breast-cancer cells to drug-induced apoptosis

1 reference

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Expression of the bcl-2 gene family in normal and malignant breast tissue: low bax-alpha expression in tumor cells correlates with resistance towards apoptosis

1 reference

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7 January 2021

based on heuristic

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Relapse in childhood acute lymphoblastic leukemia is associated with a decrease of the Bax/Bcl-2 ratio and loss of spontaneous caspase-3 processing in vivo

1 reference

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7 January 2021

based on heuristic

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Activation of caspase-8 in drug-induced apoptosis of B-lymphoid cells is independent of CD95/Fas receptor-ligand interaction and occurs downstream of caspase-3.

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Response to cladribine in previously treated patients with chronic lymphocytic leukaemia identified by ex vivo assessment of drug sensitivity by DiSC assay.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402539

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Prognosis for fludarabine therapy of chronic lymphocytic leukaemia based on ex vivo drug response by DiSC assay.

1 reference

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Methylprednisolone in advanced chronic lymphocytic leukaemia: rationale for, and effectiveness of treatment suggested by DiSC assay.

1 reference

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based on heuristic

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Enhanced ex vivo drug sensitivity testing of chronic lymphocytic leukaemia using refined DiSC assay methodology

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402539

7 January 2021

based on heuristic

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Measurement of protein using bicinchoninic acid

1 reference

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7 January 2021

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Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1 reference

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7 January 2021

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Growth factors stimulate phosphorylation of CTP:phosphocholine cytidylyltransferase in HeLa cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402539

7 January 2021

based on heuristic

inferred from DOI database lookup

Ex vivo assessment of drug response by differential staining cytotoxicity (DiSC) assay suggests a biological basis for equality of chemotherapy irrespective of age for patients with chronic lymphocytic leukaemia

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Analysis of p53/BAX/p16(ink4a/CDKN2) in esophageal squamous cell carcinoma: high BAX and p16(ink4a/CDKN2) identifies patients with good prognosis

1 reference

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7 January 2021

based on heuristic

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In vitro chemosensitivity of chronic lymphocytic leukaemia to purine analogues--correlation with clinical course.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402539

7 January 2021

based on heuristic

inferred from DOI database lookup

Bcl-2, Bax and p53 expression in B-CLL in relation to in vitro survival and clinical progression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402539

7 January 2021

based on heuristic

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Regulation of clinical chemoresistance by bcl-2 and bax oncoproteins in B-cell chronic lymphocytic leukaemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402539

7 January 2021

based on heuristic

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The kiss of death: promises and failures of death receptors and ligands in cancer therapy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402539

7 January 2021

based on heuristic

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Overexpression of caspase-3 restores sensitivity for drug-induced apoptosis in breast cancer cell lines with acquired drug resistance

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402539

7 January 2021

based on heuristic

inferred from DOI database lookup

Management of chronic lymphocytic leukaemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402539

7 January 2021

based on heuristic

inferred from DOI database lookup

Prediction of prognosis following fludarabine used as secondary therapy for chronic lymphocytic leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402539

7 January 2021

based on heuristic

inferred from DOI database lookup

Nucleotide requirements for the in vitro activation of the apoptosis protein-activating factor-1-mediated caspase pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402539

7 January 2021

based on heuristic

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Induction of an apoptotic program in cell-free extracts by 2-chloro-2'-deoxyadenosine 5'-triphosphate and cytochrome c

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402539

7 January 2021

based on heuristic

inferred from DOI database lookup

De novo acute B cell leukemia/lymphoma with t(14;18)

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402539

7 January 2021

based on heuristic

inferred from DOI database lookup

Positive and negative regulation of apoptotic pathways by cytotoxic agents in hematological malignancies.

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Characterisation of BCL2-JH rearrangements in follicular lymphoma: PCR detection of 3' BCL2 breakpoints and evidence of a new cluster

1 reference

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7 January 2021

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Combined effects of aberrant MEK1 activity and BCL2 overexpression on relieving the cytokine dependency of human and murine hematopoietic cells.

1 reference

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7 January 2021

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Synergy between Raf and BCL2 in abrogating the cytokine dependency of hematopoietic cells.

1 reference

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based on heuristic

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Drug resistance factors in acute myeloid leukemia: a comparative analysis

1 reference

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based on heuristic

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Clinical significance of CD95, Bcl-2 and Bax expression and CD95 function in adult de novo acute myeloid leukemia in context of P-glycoprotein function, maturation stage, and cytogenetics.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402539

7 January 2021

based on heuristic

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Bcl-2 family members in childhood acute lymphoblastic leukemia: relationships with features at presentation, in vitro and in vivo drug response and long-term clinical outcome.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402539

7 January 2021

based on heuristic

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Bax directly induces release of cytochrome c from isolated mitochondria

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402539

7 January 2021

based on heuristic

inferred from DOI database lookup

Mitochondrial control of cell death

1 reference

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based on heuristic

inferred from DOI database lookup

Bcl-2 family proteins

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Correlation of bcl-2 with P-glycoprotein expression in chronic lymphocytic leukaemia and other haematological neoplasms but of neither marker with ex vivo chemosensitivity or patient survival

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

The most unkindest cut of all: on the multiple roles of mammalian caspases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402539

7 January 2021

based on heuristic

inferred from DOI database lookup

Noncaspase proteases in apoptosis

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Protease inhibitor-induced apoptosis: accumulation of wt p53, p21WAF1/CIP1, and induction of apoptosis are independent markers of proteasome inhibition

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402539

7 January 2021

based on heuristic

inferred from DOI database lookup

Cell death beyond apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402539

7 January 2021

based on heuristic

inferred from DOI database lookup

Overexpression of Bax gene sensitizes K562 erythroleukemia cells to apoptosis induced by selective chemotherapeutic agents

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402539

7 January 2021

based on heuristic

inferred from DOI database lookup

In vitro evaluation of B-CLL cells apoptotic responses to irradiation.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402539

7 January 2021

based on heuristic

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Development of cyclin-dependent kinase modulators as novel therapeutic approaches for hematological malignancies

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402539

7 January 2021

based on heuristic

inferred from DOI database lookup

Theophylline-induced B-CLL apoptosis is partly dependent on cyclic AMP production but independent of CD38 expression and endogenous IL-10 production

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402539

7 January 2021

based on heuristic

inferred from DOI database lookup

Potentiation of antitumor effects of cyclophosphamide derivatives in B-chronic lymphocytic leukemia cells by 2-chloro-2'-deoxyadenosine

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1038/SJ.LEU.2402539

1 reference

Europe PubMed Central

23 July 2017

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1 reference

Europe PubMed Central

23 July 2017

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