(Q33203713)

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Limited lentiviral transgene expression with increasing copy number in an MGMT selection model: lack of copy number selection by drug treatment

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scholarly article

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Europe PubMed Central

23 July 2017

Limited lentiviral transgene expression with increasing copy number in an MGMT selection model: lack of copy number selection by drug treatment (English)

1 reference

Europe PubMed Central

23 July 2017

author name string

Steven P Zielske

1

1 reference

Europe PubMed Central

23 July 2017

Karen T Lingas

2

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Europe PubMed Central

23 July 2017

Yan Li

3

1 reference

Europe PubMed Central

23 July 2017

Stanton L Gerson

4

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Europe PubMed Central

23 July 2017

publication date

1 June 2004

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Europe PubMed Central

23 July 2017

Molecular Therapy

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Europe PubMed Central

23 July 2017

9

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Europe PubMed Central

23 July 2017

6

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Europe PubMed Central

23 July 2017

923-931

1 reference

Europe PubMed Central

23 July 2017

Transcription start regions in the human genome are favored targets for MLV integration

1 reference

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HIV-1 integration in the human genome favors active genes and local hotspots

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7 January 2021

Retroviral vector integration occurs in preferred genomic targets of human bone marrow-repopulating cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2004.02.017

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Gene transfer by lentiviral vectors is limited by nuclear translocation and rescued by HIV-1 pol sequences

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The degree of phenotypic correction of murine beta -thalassemia intermedia following lentiviral-mediated transfer of a human gamma-globin gene is influenced by chromosomal position effects and vector copy number

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7 January 2021

Dose finding with retroviral vectors: correlation of retroviral vector copy numbers in single cells with gene transfer efficiency in a cell population

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Activation of a cellular onc gene by promoter insertion in ALV-induced lymphoid leukosis

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Retrovirus-induced de novo methylation of flanking host sequences correlates with gene inactivity

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7 January 2021

Gene therapy of human severe combined immunodeficiency (SCID)-X1 disease

1 reference

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7 January 2021

Gene therapy. Seeking the cause of induced leukemias in X-SCID trial

1 reference

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7 January 2021

LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1

1 reference

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In vivo selection of MGMT(P140K) lentivirus–transduced human NOD/SCID repopulating cells without pretransplant irradiation conditioning

1 reference

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7 January 2021

Methylguanine methyltransferase-mediated in vivo selection and chemoprotection of allogeneic stem cells in a large-animal model

1 reference

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7 January 2021

In vivo selection of human hematopoietic cells in a xenograft model using combined pharmacologic and genetic manipulations

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2004.02.017

7 January 2021

Characterization of the P140K, PVP(138-140)MLK, and G156A O6-methylguanine-DNA methyltransferase mutants: implications for drug resistance gene therapy

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2004.02.017

7 January 2021

Lentiviral transduction of P140K MGMT into human CD34(+) hematopoietic progenitors at low multiplicity of infection confers significant resistance to BG/BCNU and allows selection in vitro

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Murine leukemia induced by retroviral gene marking

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Sustained correction of X-linked severe combined immunodeficiency by ex vivo gene therapy

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Myeloablation is not required to select and maintain expression of the drug-resistance gene, mutant MGMT, in primary and secondary recipients

1 reference

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7 January 2021

Cytogenetics of the chronic myeloid leukemia-derived cell line K562: karyotype clarification by multicolor fluorescence in situ hybridization, comparative genomic hybridization, and locus-specific fluorescence in situ hybridization

1 reference

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7 January 2021

Comparison of O6-alkylguanine-DNA alkyltransferase activity based on cellular DNA content in human, rat and mouse tissues.

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2004.02.017

7 January 2021

Identifiers

10.1016/J.YMTHE.2004.02.017

1 reference

Europe PubMed Central

23 July 2017

1 reference

Europe PubMed Central

23 July 2017

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