(Q33207663)

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The broad-range cyclin-dependent kinase inhibitor UCN-01 induces apoptosis in colon carcinoma cells through transcriptional suppression of the Bcl-x(L) protein.

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3 January 2020

The broad-range cyclin-dependent kinase inhibitor UCN-01 induces apoptosis in colon carcinoma cells through transcriptional suppression of the Bcl-x(L) protein (English)

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3 January 2020

colon carcinoma

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Dhatchana Moorthy

4

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3 January 2020

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Mandar R Bhonde

1

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3 January 2020

Marie-Luise Hanski

2

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3 January 2020

Roberta Magrini

3

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3 January 2020

Antje Müller

5

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3 January 2020

Edward A Sausville

6

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3 January 2020

Kimitoshi Kohno

7

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3 January 2020

Peter Wiegand

8

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3 January 2020

Peter T Daniel

9

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3 January 2020

Martin Zeitz

10

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3 January 2020

Christoph Hanski

11

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3 January 2020

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1 January 2005

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3 January 2020

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3 January 2020

24

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3 January 2020

1

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3 January 2020

148-156

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3 January 2020

Questioning the role of checkpoint kinase 2 in the p53 DNA damage response

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207842

21 January 2018

Protein kinase C inhibition by UCN-01 induces apoptosis in human glioma cells in a time-dependent fashion

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207842

21 January 2018

Regulation of Bcl-xL: a little bit of this and a little bit of STAT.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207842

21 January 2018

UCN-01, 7-hydroxyl-staurosporine, inhibits kinase activity of cyclin-dependent kinases and reduces the phosphorylation of the retinoblastoma susceptibility gene product in A549 human lung cancer cell line

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207842

21 January 2018

NF-kappaB-mediated up-regulation of Bcl-x and Bfl-1/A1 is required for CD40 survival signaling in B lymphocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207842

21 January 2018

Targeted inhibition of Stat3 with a decoy oligonucleotide abrogates head and neck cancer cell growth

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207842

21 January 2018

UCN-01: a potent abrogator of G2 checkpoint function in cancer cells with disrupted p53.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207842

21 January 2018

Enhancement of antitumor activity of mitomycin C in vitro and in vivo by UCN-01, a selective inhibitor of protein kinase C

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207842

7 January 2021

based on heuristic

inferred from DOI database lookup

Differential effects of UCN-01, staurosporine and CGP 41 251 on cell cycle progression and CDC2/cyclin B1 regulation in A431 cells synchronized at M phase by nocodazole

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207842

7 January 2021

based on heuristic

inferred from DOI database lookup

G1-checkpoint function including a cyclin-dependent kinase 2 regulatory pathway as potential determinant of 7-hydroxystaurosporine (UCN-01)-induced apoptosis and G1-phase accumulation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207842

7 January 2021

based on heuristic

inferred from DOI database lookup

Inhibition of constitutively active Stat3 suppresses growth of human ovarian and breast cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207842

7 January 2021

based on heuristic

inferred from DOI database lookup

Constitutive activation of Stat3 signaling confers resistance to apoptosis in human U266 myeloma cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207842

7 January 2021

based on heuristic

inferred from DOI database lookup

Induction of colon cancer cell death by 7-hydroxystaurosporine (UCN-01) is associated with increased p38 MAPK and decreased Bcl-xL

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207842

7 January 2021

based on heuristic

inferred from DOI database lookup

High-titer packaging cells producing recombinant retroviruses resistant to human serum

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207842

7 January 2021

based on heuristic

inferred from DOI database lookup

Guardians of cell death: the Bcl-2 family proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207842

7 January 2021

based on heuristic

inferred from DOI database lookup

Cells lacking CIP1/WAF1 genes exhibit preferential sensitivity to cisplatin and nitrogen mustard

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207842

7 January 2021

based on heuristic

inferred from DOI database lookup

Tumorigenicity, mucin production and AM-3 epitope expression in clones selected from the HT-29 colon carcinoma cell line

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207842

7 January 2021

based on heuristic

inferred from DOI database lookup

UCN-01 (7-hydroxystaurosporine) inhibits the growth of human breast cancer xenografts through disruption of signal transduction

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207842

7 January 2021

based on heuristic

inferred from DOI database lookup

The bacterial lacZ gene: an important tool for metastasis research and evaluation of new cancer therapies

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207842

7 January 2021

based on heuristic

inferred from DOI database lookup

Apoptotic response to camptothecin and 7-hydroxystaurosporine (UCN-01) in the 8 human breast cancer cell lines of the NCI Anticancer Drug Screen: multifactorial relationships with topoisomerase I, protein kinase C, Bcl-2, p53, MDM-2 and caspase path

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207842

7 January 2021

based on heuristic

inferred from DOI database lookup

Interference with PDK1-Akt survival signaling pathway by UCN-01 (7-hydroxystaurosporine).

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207842

7 January 2021

based on heuristic

inferred from DOI database lookup

7-Hydroxystaurosporine (UCN-01) induces apoptosis in human colon carcinoma and leukemia cells independently of p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207842

7 January 2021

based on heuristic

inferred from DOI database lookup

UCN-01, a selective inhibitor of protein kinase C from Streptomyces.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207842

7 January 2021

based on heuristic

inferred from DOI database lookup

Paclitaxel-induced apoptosis in BJAB cells proceeds via a death receptor-independent, caspases-3/-8-driven mitochondrial amplification loop

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207842

7 January 2021

based on heuristic

inferred from DOI database lookup

Ceramide induces mitochondrial activation and apoptosis via a Bax-dependent pathway in human carcinoma cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207842

7 January 2021

based on heuristic

inferred from DOI database lookup

Interleukin-6 promotes cervical tumor growth by VEGF-dependent angiogenesis via a STAT3 pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207842

7 January 2021

based on heuristic

inferred from DOI database lookup

Interaction of TAFII105 with selected p65/RelA dimers is associated with activation of subset of NF-kappa B genes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207842

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1038/SJ.ONC.1207842

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15467762%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

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1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15467762%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

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