(Q33239176)

English

Directed evolution of human T cell receptor CDR2 residues by phage display dramatically enhances affinity for cognate peptide-MHC without increasing apparent cross-reactivity

scientific article

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scholarly article

1 reference

Europe PubMed Central

24 July 2017

Directed evolution of human T cell receptor CDR2 residues by phage display dramatically enhances affinity for cognate peptide-MHC without increasing apparent cross-reactivity (English)

1 reference

Europe PubMed Central

24 July 2017

0 references

directed evolution

0 references

author name string

Steven M Dunn

1

1 reference

Europe PubMed Central

24 July 2017

Pierre J Rizkallah

2

1 reference

Europe PubMed Central

24 July 2017

Emma Baston

3

1 reference

Europe PubMed Central

24 July 2017

Tara Mahon

4

1 reference

Europe PubMed Central

24 July 2017

Brian Cameron

5

1 reference

Europe PubMed Central

24 July 2017

Ruth Moysey

6

1 reference

Europe PubMed Central

24 July 2017

Feng Gao

7

1 reference

Europe PubMed Central

24 July 2017

Malkit Sami

8

1 reference

Europe PubMed Central

24 July 2017

Jonathan Boulter

9

1 reference

Europe PubMed Central

24 July 2017

Yi Li

10

1 reference

Europe PubMed Central

24 July 2017

Bent K Jakobsen

11

1 reference

Europe PubMed Central

24 July 2017

publication date

1 April 2006

1 reference

Europe PubMed Central

24 July 2017

Protein Science

1 reference

Europe PubMed Central

24 July 2017

15

1 reference

Europe PubMed Central

24 July 2017

710-721

1 reference

Europe PubMed Central

24 July 2017

4

1 reference

Europe PubMed Central

24 July 2017

Structural and kinetic basis for heightened immunogenicity of T cell vaccines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242494

28 July 2018

High-affinity, peptide-specific T cell receptors can be generated by mutations in CDR1, CDR2 or CDR3.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242494

28 July 2018

The CCP4 suite: programs for protein crystallography

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242494

28 July 2018

Presentation of a self-peptide in two distinct conformations by a disease-associated HLA-B27 subtype

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242494

28 July 2018

CDR3 loop flexibility contributes to the degeneracy of TCR recognition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242494

28 July 2018

Positive and negative selection of T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242494

28 July 2018

The specificity of TCR/pMHC interaction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242494

28 July 2018

Implementation of molecular replacement in AMoRe

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242494

28 July 2018

Exogenous peptides presented by transporter associated with antigen processing (TAP)-deficient and TAP-competent cells: intracellular loading and kinetics of presentation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242494

28 July 2018

T cell receptor-MHC interactions up close

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242494

28 July 2018

Identification of NY-ESO-1 peptide analogues capable of improved stimulation of tumor-reactive CTL.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242494

28 July 2018

Alteration at a single amino acid residue in the T cell receptor alpha chain complementarity determining region 2 changes the differentiation of naive CD4 T cells in response to antigen from T helper cell type 1 (Th1) to Th2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242494

28 July 2018

In vitro evolution of a T cell receptor with high affinity for peptide/MHC.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242494

28 July 2018

Production of soluble alphabeta T-cell receptor heterodimers suitable for biophysical analysis of ligand binding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242494

28 July 2018

Selecting and maintaining a diverse T-cell repertoire

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242494

28 July 2018

A direct estimate of the human alphabeta T cell receptor diversity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242494

28 July 2018

The telomerase catalytic subunit is a widely expressed tumor-associated antigen recognized by cytotoxic T lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242494

28 July 2018

Structure, specificity and CDR mobility of a class II restricted single-chain T-cell receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242494

28 July 2018

Alphabeta T cell receptor interactions with syngeneic and allogeneic ligands: affinity measurements and crystallization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242494

28 July 2018

A testicular antigen aberrantly expressed in human cancers detected by autologous antibody screening

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242494

28 July 2018

Structure of the complex between human T-cell receptor, viral peptide and HLA-A2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242494

28 July 2018

Biophysical studies of T-cell receptors and their ligands

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242494

28 July 2018

Modulation of promiscuous T cell receptor recognition by mutagenesis of CDR2 residues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242494

28 July 2018

Peptide-dependent expression of HLA-B7 on antigen processing-deficient T2 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242494

28 July 2018

High human T cell lymphotropic virus type 1 (HTLV-1)-specific precursor cytotoxic T lymphocyte frequencies in patients with HTLV-1-associated neurological disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242494

28 July 2018

Shape complementarity at protein/protein interfaces

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242494

28 July 2018

The T cell repertoire may be biased in favor of MHC recognition.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242494

28 July 2018

T-cell antigen receptor genes and T-cell recognition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242494

28 July 2018

Improved methods for building protein models in electron density maps and the location of errors in these models

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242494

28 July 2018

HLA-A2-peptide complexes: refolding and crystallization of molecules expressed in Escherichia coli and complexed with single antigenic peptides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242494

28 July 2018

Directed evolution of human T-cell receptors with picomolar affinities by phage display.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242494

31 October 2018

The architecture of metal coordination groups in proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242494

31 October 2018

Specificity and degeneracy of T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242494

31 October 2018

T cell receptors: affinities, cross-reactivities, and a conformer model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242494

31 October 2018

Stable, soluble T-cell receptor molecules for crystallization and therapeutics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242494

31 October 2018

Negative selection imparts peptide specificity to the mature T cell repertoire

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242494

31 October 2018

Two-step binding mechanism for T-cell receptor recognition of peptide MHC.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242494

31 October 2018

Ligand recognition by alpha beta T cell receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242494

31 October 2018

Two human T cell receptors bind in a similar diagonal mode to the HLA-A2/Tax peptide complex using different TCR amino acids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242494

31 October 2018

How the T Cell Repertoire Becomes Peptide and MHC Specific

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2242494

31 October 2018

TCR binding to peptide-MHC stabilizes a flexible recognition interface

1 reference

https://pubmed.ncbi.nlm.nih.gov/16600963

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A very high level of crossreactivity is an essential feature of the T-cell receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/16600963

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alanine scanning mutagenesis of an alphabeta T cell receptor: mapping the energy of antigen recognition

1 reference

https://pubmed.ncbi.nlm.nih.gov/16600963

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1110/PS.051936406

1 reference

Europe PubMed Central

24 July 2017

1 reference

Europe PubMed Central

24 July 2017

1 reference

Europe PubMed Central

24 July 2017

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