(Q33240530)

24 July 2017

title

Pharmacology. Hitting the hot spots of cell signaling cascades (English)

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24 July 2017

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John Joseph Grubb Tesmer

series ordinal

1

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24 July 2017

language of work or name

English

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publication date

1 April 2006

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24 July 2017

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24 July 2017

volume

312

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24 July 2017

issue

5772

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24 July 2017

page(s)

377-378

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Small-molecule inhibitors of protein-protein interactions: progressing towards the dream

24 July 2017

cites work

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https://api.crossref.org/works/10.1126%2FSCIENCE.1126903

Interfacial inhibition of macromolecular interactions: nature's paradigm for drug discovery

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCIENCE.1126903

Unraveling hot spots in binding interfaces: progress and challenges

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCIENCE.1126903

A hot spot of binding energy in a hormone-receptor interface

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1126903

Anatomy of hot spots in protein interfaces

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1126903

Hot regions in protein--protein interactions: the organization and contribution of structurally conserved hot spot residues

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1126903

Differential targeting of Gbetagamma-subunit signaling with small molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1126903

The structure of the G protein heterotrimer Gi alpha 1 beta 1 gamma 2

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1126903

The 2.0 A crystal structure of a heterotrimeric G protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1126903

Sites for Galpha binding on the G protein beta subunit overlap with sites for regulation of phospholipase Cbeta and adenylyl cyclase

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1126903

Evidence that a protein-protein interaction 'hot spot' on heterotrimeric G protein betagamma subunits is used for recognition of a subclass of effectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1126903

Structural and molecular characterization of a preferred protein interaction surface on G protein beta gamma subunits

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1126903

Exploring protein-protein interactions with phage display

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1126903

Rational design and characterization of a Rac GTPase-specific small molecule inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1126903

Transgenic mice targeting the heart unveil G protein-coupled receptor kinases as therapeutic targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1126903

21 January 2018

Identifiers

DOI

10.1126/SCIENCE.1126903

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24 July 2017

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