(Q33259933)

24 July 2017

Leadlikeness and structural diversity of synthetic screening libraries (English)

1 reference

24 July 2017

Herman J Verheij

1

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24 July 2017

1 August 2006

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24 July 2017

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24 July 2017

10

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24 July 2017

3

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24 July 2017

377-388

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https://scigraph.springernature.com/pub.10.1007/s11030-006-9040-6

24 July 2017

0 references

cites work

A new approach to finding natural chemical structure classes

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12 December 2020

A ‘Rule of Three’ for fragment-based lead discovery?

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12 December 2020

Drug-like index: a new approach to measure drug-like compounds and their diversity

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12 December 2020

A Common Mechanism Underlying Promiscuous Inhibitors from Virtual and High-Throughput Screening

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12 December 2020

Development of a virtual screening method for identification of "frequent hitters" in compound libraries

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12 December 2020

Examination of the computed molecular properties of compounds selected for clinical development.

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12 December 2020

Lead- and drug-like compounds: the rule-of-five revolution

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12 December 2020

CheD: chemical database compilation tool, Internet server, and client for SQL servers

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12 December 2020

A structure-permeability study of small drug-like molecules.

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12 December 2020

Chemical information management in drug discovery: optimizing the computational and combinatorial chemistry interfaces.

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12 December 2020

Nonleadlikeness and leadlikeness in biochemical screening

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12 December 2020

Drugs, leads, and drug-likeness: an analysis of some recently launched drugs

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12 December 2020

ALARM NMR: a rapid and robust experimental method to detect reactive false positives in biochemical screens

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12 December 2020

The Design of Leadlike Combinatorial Libraries

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12 December 2020

Molecular properties that influence the oral bioavailability of drug candidates

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12 December 2020

Polar molecular surface as a dominating determinant for oral absorption and brain penetration of drugs

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12 December 2020

Comparison of the NCI open database with seven large chemical structural databases.

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12 December 2020

The properties of known drugs. 1. Molecular frameworks

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12 December 2020

Computational methods for the prediction of 'drug-likeness'

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12 December 2020

Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

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12 December 2020

Systematic analysis of large screening sets in drug discovery.

1 reference

12 December 2020

Pursuing the leadlikeness concept in pharmaceutical research.

1 reference

12 December 2020

Drug-like annotation and duplicate analysis of a 23-supplier chemical database totalling 2.7 million compounds

1 reference

12 December 2020

Current trends in lead discovery: are we looking for the appropriate properties?

1 reference

12 December 2020

Is there a difference between leads and drugs? A historical perspective

1 reference

12 December 2020

Drug-like properties and the causes of poor solubility and poor permeability

1 reference

12 December 2020

Molecular complexity and its impact on the probability of finding leads for drug discovery

1 reference

12 December 2020

10.1007/S11030-006-9040-6

Identifiers

DOI

1 reference

release_bv7fxoyek5ctjmjhzqs6x527e4

24 July 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/bv7fxoyek5ctjmjhzqs6x527e4

24 November 2022

mapped directly with Wikidata item

PubMed ID

17031539

1 reference

PubMed ID

17031539