(Q33265351)

24 July 2017

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title

Wnt signalling in the mouse intestine (English)

1 reference

24 July 2017

A R Clarke

1

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24 July 2017

language of work or name

English

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publication date

1 December 2006

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24 July 2017

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24 July 2017

volume

25

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24 July 2017

issue

57

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24 July 2017

page(s)

7512-7521

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Crypt-restricted proliferation and commitment to the Paneth cell lineage following Apc loss in the mouse intestine.

24 July 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210065

7 January 2021

Smad4 haploinsufficiency in mouse models for intestinal cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210065

7 January 2021

The 'just-right' signaling model: APC somatic mutations are selected based on a specific level of activation of the beta-catenin signaling cascade.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210065

7 January 2021

Beta-catenin and TCF mediate cell positioning in the intestinal epithelium by controlling the expression of EphB/ephrinB

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210065

7 January 2021

EphB receptor activity suppresses colorectal cancer progression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210065

7 January 2021

c-Myc is required for the formation of intestinal crypts but dispensable for homeostasis of the adult intestinal epithelium

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210065

7 January 2021

SOX9 is an intestine crypt transcription factor, is regulated by the Wnt pathway, and represses the CDX2 and MUC2 genes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210065

7 January 2021

Mouse axin and axin2/conductin proteins are functionally equivalent in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210065

7 January 2021

How good are rodent models of carcinogenesis in predicting efficacy in humans? A systematic review and meta-analysis of colon chemoprevention in rats, mice and men

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210065

7 January 2021

Persistent STAT3 activation in colon cancer is associated with enhanced cell proliferation and tumor growth

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210065

7 January 2021

Genetic identification of Mom-1, a major modifier locus affecting Min-induced intestinal neoplasia in the mouse

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210065

7 January 2021

Mutations in the APC tumour suppressor gene cause chromosomal instability

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210065

7 January 2021

Wnt3a-/--like phenotype and limb deficiency in Lef1(-/-)Tcf1(-/-) mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210065

7 January 2021

Molecular properties of adult mouse gastric and intestinal epithelial progenitors in their niches

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210065

7 January 2021

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210065

7 January 2021

Hindgut defects and transformation of the gastro-intestinal tract in Tcf4(-/-)/Tcf1(-/-) embryos

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210065

7 January 2021

Tumor induction by an endogenous K-ras oncogene is highly dependent on cellular context

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210065

7 January 2021

Activation of nuclear hormone receptor peroxisome proliferator-activated receptor-delta accelerates intestinal adenoma growth

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210065

7 January 2021

Aberrant Wnt/beta-catenin signaling can induce chromosomal instability in colon cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210065

7 January 2021

Genetic basis of variation in adenoma multiplicity in ApcMin/+ Mom1S mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210065

7 January 2021

Genome-wide prediction of mammalian enhancers based on analysis of transcription-factor binding affinity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210065

7 January 2021

WNT/beta-catenin pathway up-regulates Stat3 and converges on LIF to prevent differentiation of mouse embryonic stem cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210065

7 January 2021

Intestinal polyposis in mice with a dominant stable mutation of the beta-catenin gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210065

7 January 2021

De novo crypt formation and juvenile polyposis on BMP inhibition in mouse intestine

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210065

7 January 2021

Peroxisome proliferator-activated receptor-delta attenuates colon carcinogenesis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210065

7 January 2021

BMP signaling inhibits intestinal stem cell self-renewal through suppression of Wnt-beta-catenin signaling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210065

7 January 2021

Ectopic expression of Oct-4 blocks progenitor-cell differentiation and causes dysplasia in epithelial tissues

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210065

7 January 2021

EphB receptors coordinate migration and proliferation in the intestinal stem cell niche

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210065

7 January 2021

Mice null for Frizzled4 (Fzd4-/-) are infertile and exhibit impaired corpora lutea formation and function

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210065

7 January 2021

Cyclin D1 genetic heterozygosity regulates colonic epithelial cell differentiation and tumor number in ApcMin mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210065

7 January 2021

Inducible Cre-mediated control of gene expression in the murine gastrointestinal tract: effect of loss of beta-catenin

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210065

7 January 2021

Targeted expression of oncogenic K-ras in intestinal epithelium causes spontaneous tumorigenesis in mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210065

7 January 2021

Achaete-scute like 2 (ascl2) is a target of Wnt signalling and is upregulated in intestinal neoplasia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210065

7 January 2021

A role for the Adenomatous Polyposis Coli protein in chromosome segregation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210065

7 January 2021

Cbfa1-independent decrease in osteoblast proliferation, osteopenia, and persistent embryonic eye vascularization in mice deficient in Lrp5, a Wnt coreceptor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210065

7 January 2021

The Wnt co-receptors Lrp5 and Lrp6 are essential for gastrulation in mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210065

7 January 2021

Apc modulates embryonic stem-cell differentiation by controlling the dosage of beta-catenin signaling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210065

7 January 2021

Mitogenic influence of human R-spondin1 on the intestinal epithelium

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210065

7 January 2021

Depletion of epithelial stem-cell compartments in the small intestine of mice lacking Tcf-4

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210065

7 January 2021

Essential requirement for Wnt signaling in proliferation of adult small intestine and colon revealed by adenoviral expression of Dickkopf-1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210065

7 January 2021

Phospholipase A2 group IIA expression in gastric adenocarcinoma is associated with prolonged survival and less frequent metastasis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210065

7 January 2021

The threshold level of adenomatous polyposis coli protein for mouse intestinal tumorigenesis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210065

7 January 2021

Negative feedback loop of Wnt signaling through upregulation of conductin/axin2 in colorectal and liver tumors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210065

7 January 2021

The secretory phospholipase A2 gene is a candidate for the Mom1 locus, a major modifier of ApcMin-induced intestinal neoplasia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210065

7 January 2021

Epithelial hedgehog signals pattern the intestinal crypt-villus axis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210065

7 January 2021

Gene expression profiling of intestinal epithelial cell maturation along the crypt-villus axis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210065

7 January 2021

The rac activator Tiam1 is a Wnt-responsive gene that modifies intestinal tumor development.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210065

7 January 2021

Modulation of notch processing by gamma-secretase inhibitors causes intestinal goblet cell metaplasia and induction of genes known to specify gut secretory lineage differentiation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210065

7 January 2021

Enhanced CpG mutability and tumorigenesis in MBD4-deficient mice.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210065

7 January 2021

Rapid loss of intestinal crypts upon conditional deletion of the Wnt/Tcf-4 target gene c-Myc

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210065

7 January 2021

Interaction of phosphorylated c-Jun with TCF4 regulates intestinal cancer development

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210065

7 January 2021

Synergistic action of Wnt and LIF in maintaining pluripotency of mouse ES cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210065

7 January 2021

Foxf1 and Foxf2 control murine gut development by limiting mesenchymal Wnt signaling and promoting extracellular matrix production

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210065

7 January 2021

Loss of Apc heterozygosity and abnormal tissue building in nascent intestinal polyps in mice carrying a truncated Apc gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210065

7 January 2021

Foxl1 is a mesenchymal Modifier of Min in carcinogenesis of stomach and colon

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210065

7 January 2021

An LDL-receptor-related protein mediates Wnt signalling in mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210065

7 January 2021

Canonical Wnt signals are essential for homeostasis of the intestinal epithelium

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210065

7 January 2021

Kaiso-deficient mice show resistance to intestinal cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210065

7 January 2021

Spontaneous Aberrant Crypt Foci in Apc1638N Mice with a Mutant Apc Allele

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210065

7 January 2021

Colonic tumorigenesis in BubR1+/-ApcMin/+ compound mutant mice is linked to premature separation of sister chromatids and enhanced genomic instability

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210065

7 January 2021

PPARdelta status and Apc-mediated tumourigenesis in the mouse intestine

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210065

7 January 2021

Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210065

7 January 2021

Loss of imprinting of Igf2 alters intestinal maturation and tumorigenesis in mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210065

7 January 2021

Deficiency of Mbd2 suppresses intestinal tumorigenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210065

7 January 2021

Loss of Apc in vivo immediately perturbs Wnt signaling, differentiation, and migration

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210065

7 January 2021

Cyclin D1 is not an immediate target of beta-catenin following Apc loss in the intestine

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210065

7 January 2021

Loss of Apc allows phenotypic manifestation of the transforming properties of an endogenous K-ras oncogene in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210065

7 January 2021

Myh deficiency enhances intestinal tumorigenesis in multiple intestinal neoplasia (ApcMin/+) mice.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210065

7 January 2021

Identification of the modifier of Min 2 (Mom2) locus, a new mutation that influences Apc-induced intestinal neoplasia.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210065

7 January 2021

wnt3a but not wnt11 supports self-renewal of embryonic stem cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210065

7 January 2021

Loss of Apc and the entire chromosome 18 but absence of mutations at the Ras and Tp53 genes in intestinal tumors from Apc1638N, a mouse model for Apc-driven carcinogenesis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210065

7 January 2021

E-cadherin and adenomatous polyposis coli mutations are synergistic in intestinal tumor initiation in mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210065

7 January 2021

The catenin p120ctn inhibits Kaiso-mediated transcriptional repression of the beta-catenin/TCF target gene matrilysin

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210065

7 January 2021

Molecular features of adult mouse small intestinal epithelial progenitors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210065

7 January 2021

Multiple intestinal neoplasia caused by a mutation in the murine homolog of the APC gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210065

7 January 2021

Epigenetic inactivation of SFRP genes allows constitutive WNT signaling in colorectal cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210065

7 January 2021

Foxl1-deficient mice exhibit aberrant epithelial cell positioning resulting from dysregulated EphB/EphrinB expression in the small intestine

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210065

7 January 2021

DNA methyltransferase deficiency modifies cancer susceptibility in mice lacking DNA mismatch repair

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210065

7 January 2021

Frat is dispensable for canonical Wnt signaling in mammals

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210065

7 January 2021

Indian Hedgehog is an antagonist of Wnt signaling in colonic epithelial cell differentiation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210065

7 January 2021

The beta-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210065

7 January 2021

Wnt signalling induces maturation of Paneth cells in intestinal crypts

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210065

7 January 2021

Notch/gamma-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210065

7 January 2021

Effects of forced expression of an NH2-terminal truncated beta-Catenin on mouse intestinal epithelial homeostasis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210065

7 January 2021

Selection of multipotent stem cells during morphogenesis of small intestinal crypts of Lieberkuhn is perturbed by stimulation of Lef-1/beta-catenin signaling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210065

7 January 2021

Haploid loss of the tumor suppressor Smad4/Dpc4 initiates gastric polyposis and cancer in mice.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210065

7 January 2021

Opposing effects of DNA hypomethylation on intestinal and liver carcinogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210065

7 January 2021

Notch signaling regulates the differentiation of post-mitotic intestinal epithelial cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210065

7 January 2021

Novel cross talk of Kruppel-like factor 4 and beta-catenin regulates normal intestinal homeostasis and tumor repression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210065

7 January 2021

Induction of HDAC2 expression upon loss of APC in colorectal tumorigenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210065

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1210065

1 reference

Dimensions Publication ID

24 July 2017

1052574786

0 references

1 reference