(Q33269648)

English

A single amino acid substitution (Cys249Trp) in Crb1 causes retinal degeneration and deregulates expression of pituitary tumor transforming gene Pttg1.

scientific article

In more languages

default values for all languages

No label defined

No description defined

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

24 July 2017

A single amino acid substitution (Cys249Trp) in Crb1 causes retinal degeneration and deregulates expression of pituitary tumor transforming gene Pttg1. (English)

1 reference

Europe PubMed Central

PubMed publication ID

24 July 2017

Crumbs family member 1, photoreceptor morphogenesis associated

1 reference

GOA release 2020-03-11

retinal degeneration

1 reference

based on heuristic

inferred from title

Serge A van de Pavert

1

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6672796&resulttype=core&format=json

16 May 2020

10

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6672796&resulttype=core&format=json

16 May 2020

author name string

Jan Meuleman

2

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6672796&resulttype=core&format=json

16 May 2020

Anna Malysheva

3

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6672796&resulttype=core&format=json

16 May 2020

Wendy M Aartsen

4

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6672796&resulttype=core&format=json

16 May 2020

Inge Versteeg

5

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6672796&resulttype=core&format=json

16 May 2020

Felix Tonagel

6

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6672796&resulttype=core&format=json

16 May 2020

Willem Kamphuis

7

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6672796&resulttype=core&format=json

16 May 2020

Chris J McCabe

8

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6672796&resulttype=core&format=json

16 May 2020

Mathias W Seeliger

9

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6672796&resulttype=core&format=json

16 May 2020

language of work or name

0 references

publication date

1 January 2007

1 reference

Europe PubMed Central

PubMed publication ID

24 July 2017

Journal of Neuroscience

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6672796&resulttype=core&format=json

16 May 2020

27

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6672796&resulttype=core&format=json

16 May 2020

3

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6672796&resulttype=core&format=json

16 May 2020

564-573

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6672796&resulttype=core&format=json

16 May 2020

Early involvement of estrogen-induced pituitary tumor transforming gene and fibroblast growth factor expression in prolactinoma pathogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17234588

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nuclear translocation and transcription regulation by the membrane-associated guanylate kinase CASK/LIN-2

1 reference

https://pubmed.ncbi.nlm.nih.gov/17234588

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A deletion in a photoreceptor-specific nuclear receptor mRNA causes retinal degeneration in the rd7 mouse

1 reference

https://pubmed.ncbi.nlm.nih.gov/17234588

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pituitary tumor transforming gene causes aneuploidy and p53-dependent and p53-independent apoptosis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17234588

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

New views on RPE65 deficiency: the rod system is the source of vision in a mouse model of Leber congenital amaurosis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17234588

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mice lacking pituitary tumor transforming gene show testicular and splenic hypoplasia, thymic hyperplasia, thrombocytopenia, aberrant cell cycle progression, and premature centromere division

1 reference

https://pubmed.ncbi.nlm.nih.gov/17234588

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isolation of Crb1, a mouse homologue of Drosophila crumbs, and analysis of its expression pattern in eye and brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/17234588

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Crumbs, the Drosophila homologue of human CRB1/RP12, is essential for photoreceptor morphogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17234588

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Maguk protein, Pals1, functions as an adapter, linking mammalian homologues of Crumbs and Discs Lost

1 reference

https://pubmed.ncbi.nlm.nih.gov/17234588

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular genetics of Leber congenital amaurosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17234588

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes

1 reference

https://pubmed.ncbi.nlm.nih.gov/17234588

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human securin interacts with p53 and modulates p53-mediated transcriptional activity and apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17234588

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Drosophila crumbs is required to inhibit light-induced photoreceptor degeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/17234588

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DNA damage-induced inhibition of securin expression is mediated by p53.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17234588

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pituitary tumor transforming gene-null male mice exhibit impaired pancreatic beta cell proliferation and diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/17234588

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CRB1 is essential for external limiting membrane integrity and photoreceptor morphogenesis in the mammalian retina

1 reference

https://pubmed.ncbi.nlm.nih.gov/17234588

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Connective tissue growth factor is up-regulated in the diabetic retina: amelioration by angiotensin-converting enzyme inhibition

1 reference

https://pubmed.ncbi.nlm.nih.gov/17234588

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ischemia-induced changes of AMPA-type glutamate receptor subunit expression pattern in the rat retina: a real-time quantitative PCR study

1 reference

https://pubmed.ncbi.nlm.nih.gov/17234588

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PTTG/securin activates expression of p53 and modulates its function

1 reference

https://pubmed.ncbi.nlm.nih.gov/17234588

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Crumbs homologue 1 is required for maintenance of photoreceptor cell polarization and adhesion during light exposure

1 reference

https://pubmed.ncbi.nlm.nih.gov/17234588

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CRB1 mutation spectrum in inherited retinal dystrophies

1 reference

https://pubmed.ncbi.nlm.nih.gov/17234588

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Crumbs homologue 1 in polarity and blindness.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17234588

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overexpression of human pituitary tumor transforming gene (hPTTG), is regulated by beta-catenin /TCF pathway in human esophageal squamous cell carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/17234588

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Membrane-associated guanylate kinase proteins MPP4 and MPP5 associate with Veli3 at distinct intercellular junctions of the neurosensory retina

1 reference

https://pubmed.ncbi.nlm.nih.gov/17234588

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PTTG's C-terminal PXXP motifs modulate critical cellular processes in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/17234588

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ectopic expression of PTTG1/securin promotes tumorigenesis in human embryonic kidney cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/17234588

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The genomic response to retinal disease and injury: evidence for endothelin signaling from photoreceptors to glia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17234588

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MPP5 recruits MPP4 to the CRB1 complex in photoreceptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/17234588

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vivo confocal imaging of the retina in animal models using scanning laser ophthalmoscopy

1 reference

https://pubmed.ncbi.nlm.nih.gov/17234588

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The neuroprotective WldS gene regulates expression of PTTG1 and erythroid differentiation regulator 1-like gene in mice and human cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/17234588

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MPP3 is recruited to the MPP5 protein scaffold at the retinal outer limiting membrane

1 reference

https://pubmed.ncbi.nlm.nih.gov/17234588

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mpp4 recruits Psd95 and Veli3 towards the photoreceptor synapse

1 reference

https://pubmed.ncbi.nlm.nih.gov/17234588

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pals1/Mpp5 is required for correct localization of Crb1 at the subapical region in polarized Muller glia cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/17234588

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isolation and characterization of a pituitary tumor-transforming gene (PTTG)

1 reference

https://pubmed.ncbi.nlm.nih.gov/17234588

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure, expression, and function of human pituitary tumor-transforming gene (PTTG)

1 reference

https://pubmed.ncbi.nlm.nih.gov/17234588

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.3496-06.2007

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6672796&resulttype=core&format=json

16 May 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6672796&resulttype=core&format=json

16 May 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6672796&resulttype=core&format=json

16 May 2020

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q33269648&oldid=1584916255"