(Q33269667)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17235330%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

title

Predictive value of known and novel alleles of CYP2B6 for efavirenz plasma concentrations in HIV-infected individuals (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17235330%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

1 reference

4

1 reference

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24 December 2019

Laurent Arthur Decosterd

6

1 reference

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24 December 2019

Huldrych F Günthard

9

1 reference

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24 December 2019

author name string

M Rotger

1

1 reference

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24 December 2019

H Tegude

2

1 reference

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24 December 2019

S Colombo

3

1 reference

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24 December 2019

H Furrer

5

1 reference

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24 December 2019

J Blievernicht

7

1 reference

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24 December 2019

T Saussele

8

1 reference

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24 December 2019

M Schwab

10

1 reference

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24 December 2019

M Eichelbaum

11

1 reference

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24 December 2019

A Telenti

12

1 reference

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24 December 2019

U M Zanger

13

1 reference

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24 December 2019

language of work or name

English

0 references

publication date

18 January 2007

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17235330%20AND%20SRC:MED&resulttype=core&format=json

Clinical Pharmacology & Therapeutics

24 December 2019

published in

1 reference

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24 December 2019

volume

81

1 reference

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24 December 2019

issue

4

1 reference

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24 December 2019

page(s)

557-566

1 reference

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Population pharmacokinetics and effects of efavirenz in patients with human immunodeficiency virus infection

24 December 2019

cites work

1 reference

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The cytochrome P450 2B6 (CYP2B6) is the main catalyst of efavirenz primary and secondary metabolism: implication for HIV/AIDS therapy and utility of efavirenz as a substrate marker of CYP2B6 catalytic activity

21 January 2018

1 reference

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Influence of 516G>T polymorphisms at the gene encoding the CYP450-2B6 isoenzyme on efavirenz plasma concentrations in HIV-infected subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100072

Homozygous CYP2B6 *6 (Q172H and K262R) correlates with high plasma efavirenz concentrations in HIV-1 patients treated with standard efavirenz-containing regimens.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100072

Highly variable mRNA expression and splicing of L-type voltage-dependent calcium channel alpha subunit 1C in human heart tissues

21 January 2018

1 reference

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Pharmacogenetic determinants of interindividual variability in bupropion hydroxylation by cytochrome P450 2B6 in human liver microsomes

21 January 2018

1 reference

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Hepatic CYP2B6 expression: gender and ethnic differences and relationship to CYP2B6 genotype and CAR (constitutive androstane receptor) expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100072

Multiple novel nonsynonymous CYP2B6 gene polymorphisms in Caucasians: demonstration of phenotypic null alleles

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100072

A natural CYP2B6 TATA box polymorphism (-82T--> C) leading to enhanced transcription and relocation of the transcriptional start site.

21 January 2018

1 reference

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Genetic variation in eleven phase I drug metabolism genes in an ethnically diverse population

21 January 2018

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Functional characterization of cytochrome P450 2B6 allelic variants

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100072

Bupropion and 4-OH-bupropion pharmacokinetics in relation to genetic polymorphisms in CYP2B6

21 January 2018

1 reference

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Baculovirus vectors: novel mammalian cell gene-delivery vehicles and their applications

21 January 2018

1 reference

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Cytochrome P450 2D6: overview and update on pharmacology, genetics, biochemistry

21 January 2018

1 reference

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Interpatient variability in the pharmacokinetics of the HIV non-nucleoside reverse transcriptase inhibitor efavirenz: the effect of gender, race, and CYP2B6 polymorphism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100072

A single nucleotide polymorphism of CYP2b6 found in Japanese enhances catalytic activity by autoactivation

21 January 2018

1 reference

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The repressed nuclear receptor CAR responds to phenobarbital in activating the human CYP2B6 gene

21 January 2018

1 reference

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A novel distal enhancer module regulated by pregnane X receptor/constitutive androstane receptor is essential for the maximal induction of CYP2B6 gene expression

21 January 2018

1 reference

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A chemiluminescent assay for quantitation of β-galactosidase in the femtogram range: Application to quantitation of β-galactosidase in lacZ-transfected cells

21 January 2018

1 reference

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Measurement of protein using bicinchoninic acid

21 January 2018

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Potent Mechanism-Based Inhibition of Human CYP2B6 by Clopidogrel and Ticlopidine

21 January 2018

1 reference

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cDNA cloning and sequence and cDNA-directed expression of human P450 IIB1: identification of a normal and two variant cDNAs derived from the CYP2B locus on chromosome 19 and differential expression of the IIB mRNAs in human liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100072

Extensive genetic polymorphism in the human CYP2B6 gene with impact on expression and function in human liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100072

7 January 2021

Pharmacogenetics of HIV therapy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100072

7 January 2021

Influence of CYP2B6 polymorphism on plasma and intracellular concentrations and toxicity of efavirenz and nevirapine in HIV-infected patients

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100072

7 January 2021

Genetic variability of CYP2B6 in populations of African and Asian origin: allele frequencies, novel functional variants, and possible implications for anti-HIV therapy with efavirenz

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100072

7 January 2021

Multilocus genetic interactions and response to efavirenz-containing regimens: an adult AIDS clinical trials group study

1 reference

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7 January 2021

Cytochrome P450 2B6 activity as measured by bupropion hydroxylation: effect of induction by rifampin and ethnicity

1 reference

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7 January 2021