(Q33285744)

25 July 2017

title

Age-related cataracts in alpha3Cx46-knockout mice are dependent on a calpain 3 isoform (English)

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25 July 2017

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Yajun Tang

1

1 reference

25 July 2017

Xiangyang Liu

2

1 reference

25 July 2017

Rebecca K Zoltoski

3

1 reference

25 July 2017

Layne A Novak

4

1 reference

25 July 2017

R Antonio Herrera

5

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25 July 2017

Isabelle Richard

6

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25 July 2017

Jer R Kuszak

7

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25 July 2017

Nalin M Kumar

8

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25 July 2017

language of work or name

English

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publication date

1 June 2007

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Investigative Ophthalmology Visual Science

25 July 2017

published in

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25 July 2017

volume

48

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25 July 2017

issue

6

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25 July 2017

page(s)

2685-2694

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An aberrant sequence in a connexin46 mutant underlies congenital cataracts.

25 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1959511

Connections between connexins, calcium, and cataracts in the lens.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1959511

Crystallins in water soluble-high molecular weight protein fractions and water insoluble protein fractions in aging and cataractous human lenses

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1959511

ATPases and lens ion balance.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1959511

Calpains: targets of cataract prevention?

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1959511

Sequence and Phylogenetic Analyses of 4 TMS Junctional Proteins of Animals: Connexins, Innexins, Claudins and Occludins

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1959511

Lens connexins alpha3Cx46 and alpha8Cx50 interact with zonula occludens protein-1 (ZO-1)

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1959511

Influence of Age, Diabetes, and Cataract on Calcium, Lipid-Calcium, and Protein-Calcium Relationships in Human Lenses

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1959511

Structural and functional diversity of connexin genes in the mouse and human genome

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1959511

Optical dysfunction of the crystalline lens in aquaporin-0-deficient mice

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1959511

Loss of calpain 3 proteolytic activity leads to muscular dystrophy and to apoptosis-associated IkappaBalpha/nuclear factor kappaB pathway perturbation in mice.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1959511

Influence of specific regions in Lp82 calpain on protein stability, activity, and localization within lens

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1959511

Human-mouse differences in the embryonic expression patterns of developmental control genes and disease genes.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1959511

Lp82 is the dominant form of calpain in young mouse lens

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1959511

Genetic factors influence cataract formation in alpha 3 connexin knockout mice

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1959511

The interrelationship of lens anatomy and optical quality. I. Non-primate lenses

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1959511

Cloning and expression of mRNA for calpain Lp82 from rat lens: splice variant of p94.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1959511

Disruption of alpha3 connexin gene leads to proteolysis and cataractogenesis in mice

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1959511

A new locus for dominant "zonular pulverulent" cataract, on chromosome 13

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1959511

Targeted disruption of the mouse alpha A-crystallin gene induces cataract and cytoplasmic inclusion bodies containing the small heat shock protein alpha B-crystallin

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1959511

The human lens intrinsic membrane protein MP70 (Cx50) gene: clonal analysis and chromosome mapping

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1959511

Philly mouse: a new model of hereditary cataract

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1959511

Calcium and the Physiology of Cataract

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1959511

Cytotoxic effects of internal calcium on lens physiology: a review

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1959511

Lens optical quality is a direct function of lens sutural architecture

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1959511

Connexin46, a novel lens gap junction protein, induces voltage-gated currents in nonjunctional plasma membrane of Xenopus oocytes

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1959511

Spatial and temporal patterns of distribution of the gap junction protein connexin43 during mouse gastrulation and organogenesis

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1959511

The alpha and gamma crystallin content in aqueous humor of eyes with clear lenses and with cataracts

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1959511

Regional distribution of Na,K-ATPase activity in porcine lens epithelium.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1959511

A comprehensive analysis of the expression of crystallins in mouse retina

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1959511

Calpain inhibitor, SJA6017, reduces the rate of formation of selenite cataract in rats

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1959511

Defining a link between gap junction communication, proteolysis, and cataract formation

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1959511

Connexin46 mutations linked to congenital cataract show loss of gap junction channel function.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1959511

Muscle-specific calpain, p94, is degraded by autolysis immediately after translation, resulting in disappearance from muscle.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1959511

Release of alpha-A sequence 158-173 correlates with a decrease in the molecular chaperone properties of native alpha-crystallin.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1959511

Distribution of non-diffusible calcium and sodium in normal and cataractous human lenses

31 October 2018

1 reference

12 December 2020

Sodium/potassium ATPase in normal and cataractous human lenses

1 reference

12 December 2020

The Emory mouse cataract: loss of soluble protein, glutathione, protein sulfhydryl and other changes

1 reference

12 December 2020

Evidence that alpha-crystallin prevents non-specific protein aggregation in the intact eye lens

1 reference

12 December 2020

Calcium ionophore induced proteolysis and cataract: inhibition by cell permeable calpain antagonists

1 reference

12 December 2020

Degradation of gamma D- and gamma s-crystallins in human lenses

1 reference

12 December 2020

Human lens phospholipid changes with age and cataract

1 reference

12 December 2020

Contribution of calpain Lp82-induced proteolysis to experimental cataractogenesis in mice

1 reference

12 December 2020

A human lens model of cortical cataract: Ca2+-induced protein loss, vimentin cleavage and opacification

1 reference

12 December 2020

Isoform-specific function and distribution of Na/K pumps in the frog lens epithelium

1 reference

12 December 2020

Determination of calcium, sodium, potassium and magnesium concentrations in human senile cataractous lenses

1 reference

12 December 2020

Mass measurements of C-terminally truncated alpha-crystallins from two-dimensional gels identify Lp82 as a major endopeptidase in rat lens

1 reference

12 December 2020

Lens structure in MIP-deficient mice

1 reference

12 December 2020

Newly identified exons encoding novel variants of p94/calpain 3 are expressed ubiquitously and overlap the alpha-glucosidase C gene

1 reference

12 December 2020

Identifiers

DOI

10.1167/IOVS.06-0926

1 reference

25 July 2017

1 reference

25 July 2017

1 reference