(Q33317564)

25 July 2017

title

Discovery of VHR phosphatase inhibitors with micromolar activity based on structure-based virtual screening (English)

1 reference

25 July 2017

1 reference

Hwangseo Park

1

1 reference

25 July 2017

Suk-Kyeong Jung

2

1 reference

25 July 2017

Dae Gwin Jeong

3

1 reference

25 July 2017

Seong Eon Ryu

4

1 reference

25 July 2017

Seung Jun Kim

5

1 reference

25 July 2017

publication date

1 June 2008

1 reference

25 July 2017

1 reference

25 July 2017

volume

3

1 reference

25 July 2017

issue

6

1 reference

25 July 2017

page(s)

877-880

1 reference

Inhibitors of protein tyrosine phosphatases: next-generation drugs?

25 July 2017

cites work

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700348

7 January 2021

Inhibitory role for dual specificity phosphatase VHR in T cell antigen receptor and CD28-induced Erk and Jnk activation

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700348

7 January 2021

Extracellular regulated kinases (ERK) 1 and ERK2 are authentic substrates for the dual-specificity protein-tyrosine phosphatase VHR. A novel role in down-regulating the ERK pathway

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700348

7 January 2021

Loss of the VHR dual-specific phosphatase causes cell-cycle arrest and senescence

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700348

7 January 2021

Tyrosine phosphorylation of VHR phosphatase by ZAP-70

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700348

7 January 2021

Negative regulation of ERK activity by VRK3-mediated activation of VHR phosphatase

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700348

7 January 2021

Crystal structure of the dual specificity protein phosphatase VHR

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700348

7 January 2021

A new VHR dual-specificity protein tyrosine phosphatase inhibitor from Dendrobium moniliforme

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700348

7 January 2021

Inhibition of VHR dual-specificity protein tyrosine phosphatase activity by flavonoids isolated from Scutellaria baicalensis: structure-activity relationships

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700348

7 January 2021

4-isoavenaciolide covalently binds and inhibits VHR, a dual-specificity phosphatase.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700348

7 January 2021

Design and synthesis of a dimeric derivative of RK-682 with increased inhibitory activity against VHR, a dual-specificity ERK phosphatase: implications for the molecular mechanism of the inhibition

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700348

7 January 2021

Synthesis of a tetronic acid library focused on inhibitors of tyrosine and dual-specificity protein phosphatases and its evaluation regarding VHR and cdc25B inhibition

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700348

7 January 2021

Novel benzofuran inhibitors of human mitogen-activated protein kinase phosphatase-1.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700348

7 January 2021

Identification of a potent inhibitor of human dual-specific phosphatase, VHR, from computer-aided and NMR-based screening to cellular effects.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700348

7 January 2021

A critical assessment of docking programs and scoring functions

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700348

7 January 2021

Ligand solvation in molecular docking.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700348

7 January 2021

Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700348

7 January 2021

Iterative partial equalization of orbital electronegativity—a rapid access to atomic charges

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700348

7 January 2021

Automated docking using a Lamarckian genetic algorithm and an empirical binding free energy function

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700348

7 January 2021

Critical assessment of the automated AutoDock as a new docking tool for virtual screening.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700348

7 January 2021

Electrostatic effects in proteins: comparison of dielectric and charge models

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700348

7 January 2021

Prediction of molecular solvation free energy based on the optimization of atomic solvation parameters with genetic algorithm.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700348

7 January 2021

Identifiers

DOI

10.1002/CMDC.200700348

1 reference

25 July 2017

1 reference