(Q33331565)

25 July 2017

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title

What can genome-wide association studies tell us about the genetics of common disease? (English)

1 reference

genome-wide association study

25 July 2017

main subject

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author name string

Mark M Iles

series ordinal

1

1 reference

25 July 2017

publication date

1 February 2008

1 reference

full work available at URL

25 July 2017

http://eprints.whiterose.ac.uk/10101/

content deliverer

White Rose Research Online

object has role

published version

copyright license

Creative Commons Attribution

0 references

https://doi.org/10.1371/journal.pgen.0040033

copyright license

Creative Commons Attribution

0 references

1 reference

25 July 2017

volume

4

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25 July 2017

issue

2

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25 July 2017

page(s)

e33

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Genetics of cardiovascular diseases: from single mutations to the whole genome

25 July 2017

cites work

1 reference

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Common sequence variants in the LOXL1 gene confer susceptibility to exfoliation glaucoma

21 June 2018

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Type 2 diabetes whole-genome association study in four populations: the DiaGen consortium

21 June 2018

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Risk alleles for multiple sclerosis identified by a genomewide study

21 June 2018

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Genomewide association analysis of coronary artery disease

21 June 2018

1 reference

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A genetic risk factor for periodic limb movements in sleep

21 June 2018

1 reference

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A common genetic risk factor for colorectal and prostate cancer

21 June 2018

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A new multipoint method for genome-wide association studies by imputation of genotypes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2323402

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

21 June 2018

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Replicating genotype-phenotype associations

21 June 2018

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Common variants on chromosomes 2q35 and 16q12 confer susceptibility to estrogen receptor-positive breast cancer

21 June 2018

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A genome-wide association study identifies alleles in FGFR2 associated with risk of sporadic postmenopausal breast cancer

21 June 2018

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A genome-wide association study implicates diacylglycerol kinase eta (DGKH) and several other genes in the etiology of bipolar disorder

21 June 2018

1 reference

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A common allele on chromosome 9 associated with coronary heart disease

21 June 2018

1 reference

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A common variant on chromosome 9p21 affects the risk of myocardial infarction

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2323402

Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2323402

A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2323402

Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2323402

A variant in CDKAL1 influences insulin response and risk of type 2 diabetes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2323402

A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2323402

A genome-wide genotyping study in patients with ischaemic stroke: initial analysis and data release

21 June 2018

1 reference

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Overcoming the winner's curse: estimating penetrance parameters from case-control data

21 June 2018

1 reference

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Population-based resequencing of ANGPTL4 uncovers variations that reduce triglycerides and increase HDL.

21 June 2018

1 reference

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A genome-wide association study identifies novel risk loci for type 2 diabetes

21 June 2018

1 reference

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Simulations provide support for the common disease-common variant hypothesis

21 June 2018

1 reference

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Coverage and power in genomewide association studies

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2323402

High-resolution whole-genome association study of Parkinson disease.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2323402

Complement factor H polymorphism in age-related macular degeneration

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2323402

Genome-wide association studies: theoretical and practical concerns

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2323402

Multiple Rare Alleles Contribute to Low Plasma Levels of HDL Cholesterol

21 June 2018

1 reference

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The International HapMap Project

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2323402

Meta-analysis of genetic association studies supports a contribution of common variants to susceptibility to common disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2323402

The allelic architecture of human disease genes: common disease-common variant... or not?

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2323402

Large upward bias in estimation of locus-specific effects from genomewide scans

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2323402

On the allelic spectrum of human disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2323402

Linkage disequilibrium in humans: models and data

21 June 2018

1 reference

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Are rare variants responsible for susceptibility to complex diseases?

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2323402

The future of genetic studies of complex human diseases

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2323402

Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2323402

Genome-wide association study identifies novel breast cancer susceptibility loci

21 June 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.0040033

Detecting disease associations due to linkage disequilibrium using haplotype tags: a class of tests and the determinants of statistical power

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.0040033

Sample size requirements for matched case-control studies of gene-environment interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.0040033

Quantification and correction of bias in tagging SNPs caused by insufficient sample size and marker density by means of haplotype-dropping

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.0040033

Genome-wide association study identifies a second prostate cancer susceptibility variant at 8q24.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.0040033

Upward bias in odds ratio estimates from genome-wide association studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.0040033

The new genomics: global views of biology

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18454206

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Guilt beyond a reasonable doubt

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18454206

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Conjuring SNPs to detect associations

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18454206

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PGEN.0040033

1 reference

10.1371/JOURNAL.PGEN.0040033

25 July 2017

Altmetric DOI

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CORE ID

87524209

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Dimensions Publication ID

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1 reference

25 July 2017

1 reference