(Q33335885)

English

BCL-2 cooperates with promyelocytic leukemia retinoic acid receptor alpha chimeric protein (PMLRARalpha) to block neutrophil differentiation and initiate acute leukemia

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scholarly article

1 reference

Europe PubMed Central

25 July 2017

BCL-2 cooperates with promyelocytic leukemia retinoic acid receptor alpha chimeric protein (PMLRARalpha) to block neutrophil differentiation and initiate acute leukemia (English)

1 reference

Europe PubMed Central

25 July 2017

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

author name string

S C Kogan

1

1 reference

Europe PubMed Central

25 July 2017

D E Brown

2

1 reference

Europe PubMed Central

25 July 2017

D B Shultz

3

1 reference

Europe PubMed Central

25 July 2017

B T Truong

4

1 reference

Europe PubMed Central

25 July 2017

V Lallemand-Breitenbach

5

1 reference

Europe PubMed Central

25 July 2017

M C Guillemin

6

1 reference

Europe PubMed Central

25 July 2017

E Lagasse

7

1 reference

Europe PubMed Central

25 July 2017

I L Weissman

8

1 reference

Europe PubMed Central

25 July 2017

J M Bishop

9

1 reference

Europe PubMed Central

25 July 2017

language of work or name

0 references

publication date

1 February 2001

1 reference

Europe PubMed Central

25 July 2017

Journal of Experimental Medicine

1 reference

Europe PubMed Central

25 July 2017

193

1 reference

Europe PubMed Central

25 July 2017

4

1 reference

Europe PubMed Central

25 July 2017

531-543

1 reference

Europe PubMed Central

25 July 2017

Role of promyelocytic leukemia (PML) protein in tumor suppression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195904

21 June 2018

Acquired, nonrandom chromosomal abnormalities associated with the development of acute promyelocytic leukemia in transgenic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195904

21 June 2018

The incidence of acute promyelocytic leukemia appears constant over most of a human lifespan, implying only one rate limiting mutation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195904

21 June 2018

Leukemia initiated by PMLRARalpha: the PML domain plays a critical role while retinoic acid-mediated transactivation is dispensable

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195904

21 June 2018

A bcr-3 isoform of RARalpha-PML potentiates the development of PML-RARalpha-driven acute promyelocytic leukemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195904

21 June 2018

BCL-2 family members and the mitochondria in apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195904

21 June 2018

Block of granulocytic differentiation of 32Dcl3 cells by AML1/ETO(MTG8) but not by highly expressed Bcl-2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195904

21 June 2018

Deconstructing a disease: RARalpha, its fusion partners, and their roles in the pathogenesis of acute promyelocytic leukemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195904

21 June 2018

Retinoic acid and arsenic synergize to eradicate leukemic cells in a mouse model of acute promyelocytic leukemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195904

21 June 2018

Apoptotic role of Fas/Fas ligand system in the regulation of erythropoiesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195904

21 June 2018

Molecular mapping of chromosome 2 deletions in murine radiation-induced AML localizes a putative tumor suppressor gene to a 1.0 cM region homologous to human chromosome segment 11p11-12.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195904

21 June 2018

PML is essential for multiple apoptotic pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195904

21 June 2018

Complete remission after treatment of acute promyelocytic leukemia with arsenic trioxide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195904

21 June 2018

The PEBP2betaMYH11 fusion created by Inv(16)(p13;q22) in myeloid leukemia impairs neutrophil maturation and contributes to granulocytic dysplasia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195904

21 June 2018

Caspases mediate retinoic acid-induced degradation of the acute promyelocytic leukemia PML/RARalpha fusion protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195904

21 June 2018

Mice defective in two apoptosis pathways in the myeloid lineage develop acute myeloblastic leukemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195904

21 June 2018

High expression of bcl-2 mRNA as a determinant of poor prognosis in acute myeloid leukemia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195904

21 June 2018

Cell death induction by the acute promyelocytic leukemia-specific PML/RARalpha fusion protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195904

21 June 2018

Oncogenic transcription factors in the human acute leukemias

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195904

21 June 2018

Modulation of p53, WAF1/p21 and BCL-2 expression during retinoic acid-induced differentiation of NB4 promyelocytic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195904

21 June 2018

Enforced expression of Bcl-2 in monocytes rescues macrophages and partially reverses osteopetrosis in op/op mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195904

21 June 2018

Targeted expression of MYCN causes neuroblastoma in transgenic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195904

21 June 2018

A retinoid-resistant acute promyelocytic leukemia subclone expresses a dominant negative PML-RAR alpha mutation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195904

21 June 2018

Acute leukemia with promyelocytic features in PML/RARalpha transgenic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195904

21 June 2018

Use of arsenic trioxide (As2O3) in the treatment of acute promyelocytic leukemia (APL): I. As2O3 exerts dose-dependent dual effects on APL cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195904

21 June 2018

A PMLRARalpha transgene initiates murine acute promyelocytic leukemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195904

21 June 2018

In vitro studies on cellular and molecular mechanisms of arsenic trioxide (As2O3) in the treatment of acute promyelocytic leukemia: As2O3 induces NB4 cell apoptosis with downregulation of Bcl-2 expression and modulation of PML-RAR alpha/PML proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195904

21 June 2018

The acute promyelocytic leukemia-specific PML-RAR alpha fusion protein inhibits differentiation and promotes survival of myeloid precursor cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195904

21 June 2018

The PML-RAR alpha gene product of the t(15;17) translocation inhibits retinoic acid-induced granulocytic differentiation and mediated transactivation in human myeloid cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195904

21 June 2018

A rapid method for measuring apoptosis and dual-color immunofluorescence by single laser flow cytometry

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195904

21 June 2018

bcl-2 inhibits apoptosis of neutrophils but not their engulfment by macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195904

21 June 2018

Dysregulated bcl-2 expression inhibits apoptosis but not differentiation of retinoic acid-induced HL-60 granulocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195904

21 June 2018

Promyelocytic leukemia-specific PML-retinoic acid alpha receptor fusion protein interferes with erythroid differentiation of human erythroleukemia K562 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195904

21 June 2018

Deregulated Bcl-2 gene expression selectively prolongs survival of growth factor-deprived hemopoietic cell lines.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195904

21 June 2018

Detection of multiple gains and losses of genetic material in ten glioma cell lines by comparative genomic hybridization.

1 reference

https://api.crossref.org/works/10.1084%2FJEM.193.4.531

21 January 2018

Incidence and implication of additional chromosome aberrations in acute promyelocytic leukaemia with translocation t(15;17)(q22;q21): a report on 50 patients

1 reference

https://api.crossref.org/works/10.1084%2FJEM.193.4.531

21 January 2018

Additional chromosome abnormalities confer worse prognosis in acute promyelocytic leukaemia.

1 reference

https://api.crossref.org/works/10.1084%2FJEM.193.4.531

21 January 2018

PML/RAR alpha fusion protein expression in normal human hematopoietic progenitors dictates myeloid commitment and the promyelocytic phenotype.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195904

31 October 2018

Clinical significance of CD95, Bcl-2 and Bax expression and CD95 function in adult de novo acute myeloid leukemia in context of P-glycoprotein function, maturation stage, and cytogenetics.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2195904

31 October 2018

Secondary cytogenetic changes in acute promyelocytic leukemia--prognostic importance in patients treated with chemotherapy alone and association with the intron 3 breakpoint of the PML gene: a Cancer and Leukemia Group B study

1 reference

https://pubmed.ncbi.nlm.nih.gov/11181704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical and laboratory evaluation of all-trans retinoic acid modulation of chemotherapy in patients with acute myelogenous leukaemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/11181704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytogenetic studies in acute promyelocytic leukemia: a survey of secondary chromosomal abnormalities

1 reference

https://pubmed.ncbi.nlm.nih.gov/11181704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High expression of bcl-2 protein in acute myeloid leukemia cells is associated with poor response to chemotherapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/11181704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The molecular basis of leukemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/11181704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential expression of BCL-2 oncoprotein and Fas antigen on normal peripheral blood and leukemic bone marrow cells. A flow cytometric analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/11181704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bcl-2 has a cell cycle inhibitory function separable from its enhancement of cell survival

1 reference

https://pubmed.ncbi.nlm.nih.gov/11181704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Altered myeloid development and acute leukemia in transgenic mice expressing PML-RAR alpha under control of cathepsin G regulatory sequences

1 reference

https://pubmed.ncbi.nlm.nih.gov/11181704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

p53-dependent apoptosis suppresses tumor growth and progression in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/11181704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bcl-2 oncoprotein expression in acute myeloid leukemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/11181704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bcl-2 protein expression in normal human bone marrow precursors and in acute myelogenous leukemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/11181704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multiparameter flow-cytometric analysis of bcl-2 and Fas expression in normal and neoplastic hematopoiesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/11181704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Terminal megakaryocytic differentiation of TF-1 cells is induced by phorbol esters and thrombopoietin and is blocked by expression of PML/RARalpha fusion protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/11181704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PML/RARalpha, a fusion protein in acute promyelocytic leukemia, prevents growth factor withdrawal-induced apoptosis in TF-1 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/11181704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An E mu-BCL-2 transgene facilitates leukaemogenesis by ionizing radiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/11181704

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1084/JEM.193.4.531

1 reference

Europe PubMed Central

25 July 2017

1 reference

Europe PubMed Central

25 July 2017

1 reference

Europe PubMed Central

25 July 2017

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