(Q33343449)

26 July 2017

title

Model-based hypothesis testing of key mechanisms in initial phase of insulin signaling (English)

1 reference

26 July 2017

1 reference

1 reference

Gunnar Cedersund

1

1 reference

26 July 2017

Jacob Roll

2

1 reference

26 July 2017

Erik Ulfhielm

3

1 reference

26 July 2017

Anna Danielsson

4

1 reference

26 July 2017

Henrik Tidefelt

5

1 reference

26 July 2017

Peter Strålfors

6

1 reference

26 July 2017

publication date

20 June 2008

1 reference

PLOS Computational Biology

26 July 2017

published in

1 reference

26 July 2017

volume

4

1 reference

26 July 2017

issue

6

1 reference

26 July 2017

page(s)

e1000096

1 reference

Creative Commons Attribution 4.0 International

26 July 2017

copyright license

start time

20 June 2008

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Role of endosomal trafficking dynamics on the regulation of hepatic insulin receptor activity: models for Fao cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2424138

Role of insulin-induced reactive oxygen species in the insulin signaling pathway

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2424138

Colocalization of insulin receptor and insulin receptor substrate-1 to caveolae in primary human adipocytes. Cholesterol depletion blocks insulin signalling for metabolic and mitogenic control

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2424138

An arginine to cysteine(252) mutation in insulin receptors from a patient with severe insulin resistance inhibits receptor internalisation but preserves signalling events

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2424138

Computational modeling of the dynamics of the MAP kinase cascade activated by surface and internalized EGF receptors

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2424138

Insulin signalling and the regulation of glucose and lipid metabolism

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2424138

Phosphorylation of PTP1B at Ser(50) by Akt impairs its ability to dephosphorylate the insulin receptor

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2424138

Phosphorylation and activation of protein tyrosine phosphatase (PTP) 1B by insulin receptor

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2424138

Insulin stimulates tyrosine phosphorylation and inactivation of protein-tyrosine phosphatase 1B in vivo

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2424138

Serine residues 1177/78/82 of the insulin receptor are required for substrate phosphorylation but not autophosphorylation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2424138

Localization of the insulin receptor in caveolae of adipocyte plasma membrane

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2424138

Inhibition of clathrin-mediated endocytosis selectively attenuates specific insulin receptor signal transduction pathways

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2424138

Insulin receptor internalization and signalling

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2424138

Chloroquine extends the lifetime of the activated insulin receptor complex in endosomes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2424138

Insulin-induced in situ phosphorylation of the insulin receptor located in the plasma membrane versus endosomes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2424138

Two steps of insulin receptor internalization depend on different domains of the beta-subunit

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2424138

Internalization and intracellular processing of insulin and insulin receptors in adipocytes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2424138

Receptor-mediated endocytosis of insulin: role of microvilli, coated pits, and coated vesicles

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2424138

Characterization of rat liver endosomal fractions. In vivo activation of insulin-stimulable receptor kinase in these structures

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2424138

Insulin-induced dephosphorylation of hormone-sensitive lipase. Correlation with lipolysis and cAMP-dependent protein kinase activity.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2424138

Insulin-induced surface redistribution regulates internalization of the insulin receptor and requires its autophosphorylation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2424138

A mathematical model of metabolic insulin signaling pathways

21 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PCBI.1000096

Modeling and simulation of intracellular dynamics: choosing an appropriate framework.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PCBI.1000096

Insulin resistance in human adipocytes occurs downstream of IRS1 after surgical cell isolation but at the level of phosphorylation of IRS1 in type 2 diabetes.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PCBI.1000096

Tyrosine phosphorylation of the insulin receptor during insulin-stimulated internalization in rat hepatoma cells.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2424138

Insulin receptor kinase following internalization in isolated rat adipocytes

31 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18551197

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Dynamics of signaling during insulin-stimulated endocytosis of its receptor in adipocytes

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18551197

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Selective activation of the rat hepatic endosomal insulin receptor kinase. Role for the endosome in insulin signaling

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18551197

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PCBI.1000096

1 reference

journals/ploscb/CedersundRUDTS08

26 July 2017

DBLP publication ID

1 reference

DBLP Dataset 2021-01-02

28 January 2021

1 reference

26 July 2017

1 reference