(Q33348982)

English

A futile cycle, formed between two ATP-dependant gamma-glutamyl cycle enzymes, gamma-glutamyl cysteine synthetase and 5-oxoprolinase: the cause of cellular ATP depletion in nephrotic cystinosis?

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

A futile cycle, formed between two ATP-dependant gamma-glutamyl cycle enzymes, gamma-glutamyl cysteine synthetase and 5-oxoprolinase: the cause of cellular ATP depletion in nephrotic cystinosis? (English)

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

author name string

Akhilesh Kumar

1

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

Anand Kumar Bachhawat

2

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

publication date

1 March 2010

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

Journal of Biosciences

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

35

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

1

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

21-25

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

Impaired activity of the gamma-glutamyl cycle in nephropathic cystinosis fibroblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/20413906

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glutathione: interorgan translocation, turnover, and metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/20413906

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of glutathione transport processes in kidney function

1 reference

https://pubmed.ncbi.nlm.nih.gov/20413906

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of gamma-glutamyl-cysteine synthetase by nonallosteric feedback inhibition by glutathione

1 reference

https://pubmed.ncbi.nlm.nih.gov/20413906

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enzymatic Conversion of 5-Oxo-L-Proline (L-Pyrrolidone Carboxylate) to L-Glutamate Coupled with Cleavage of Adenosine Triphosphate to Adenosine Diphosphate, a Reaction in the γ-Glutamyl Cycle

1 reference

https://pubmed.ncbi.nlm.nih.gov/20413906

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Partial reactions catalyzed by -glutamylcysteine synthetase and evidence for an activated glutamate intermediate.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20413906

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glutathione-degrading capacities of liver and kidney in different species

1 reference

https://pubmed.ncbi.nlm.nih.gov/20413906

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Fanconi syndrome of cystinosis: insights into the pathophysiology

1 reference

https://pubmed.ncbi.nlm.nih.gov/20413906

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased apoptosis in cystinotic fibroblasts and renal proximal tubule epithelial cells results from cysteinylation of protein kinase Cdelta.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20413906

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inborn errors in the metabolism of glutathione

1 reference

https://pubmed.ncbi.nlm.nih.gov/20413906

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

On the enzymology of amino acid transport

1 reference

https://pubmed.ncbi.nlm.nih.gov/20413906

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A novel gene encoding an integral membrane protein is mutated in nephropathic cystinosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20413906

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lysosomal cystine storage augments apoptosis in cultured human fibroblasts and renal tubular epithelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20413906

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Decreased intracellular ATP content and intact mitochondrial energy generating capacity in human cystinotic fibroblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/20413906

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pyroglutamic aciduria and nephropathic cystinosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20413906

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glutathione precursors replenish decreased glutathione pool in cystinotic cell lines

1 reference

https://pubmed.ncbi.nlm.nih.gov/20413906

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of hepatic glutathione synthesis: current concepts and controversies.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20413906

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial complex V expression and activity in cystinotic fibroblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/20413906

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cysteamine therapy for children with nephropathic cystinosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20413906

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intralysosomal cystine accumulation in mice lacking cystinosin, the protein defective in cystinosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20413906

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bovine 5-oxo-L-prolinase: simple assay method, purification, cDNA cloning, and detection of mRNA in the coronary artery

1 reference

https://pubmed.ncbi.nlm.nih.gov/20413906

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nephropathic cystinosis: late complications of a multisystemic disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/20413906

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of adenosine triphosphate (ATP) and NaK ATPase in the inhibition of proximal tubule transport with intracellular cystine loading.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20413906

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glutathione depletion and increased apoptosis rate in human cystinotic proximal tubular cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20413906

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Successful treatment of the murine model of cystinosis using bone marrow cell transplantation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20413906

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Potential role of apoptosis in development of the cystinotic phenotype

1 reference

https://pubmed.ncbi.nlm.nih.gov/20413906

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S12038-010-0004-8

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

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1 reference

https://api.fatcat.wiki/v0/release/zu4qusfojjhwjivubvskagp3li

24 November 2022

based on heuristic

mapped directly with Wikidata item

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

ResearchGate publication ID

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