(Q33366351)

26 July 2017

title

Pharmacokinetics of paclitaxel in ovarian cancer patients and genetic polymorphisms of CYP2C8, CYP3A4, and MDR1. (English)

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26 July 2017

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Miki Nakajima

1

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26 July 2017

Yuto Fujiki

2

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26 July 2017

Satoru Kyo

3

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26 July 2017

Taro Kanaya

4

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26 July 2017

Mitsuhiro Nakamura

5

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26 July 2017

Yoshiko Maida

6

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26 July 2017

Masaaki Tanaka

7

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26 July 2017

Masaki Inoue

8

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26 July 2017

Tsuyoshi Yokoi

9

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26 July 2017

publication date

1 June 2005

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The Journal of Clinical Pharmacology

26 July 2017

published in

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26 July 2017

volume

45

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26 July 2017

issue

6

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26 July 2017

page(s)

674-682

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Taxol: mechanisms of action and resistance.

26 July 2017

cites work

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https://api.crossref.org/works/10.1177%2F0091270005276204

Isolation, structural determination, and biological activity of 6 alpha-hydroxytaxol, the principal human metabolite of taxol

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270005276204

Limited oral bioavailability and active epithelial excretion of paclitaxel (Taxol) caused by P-glycoprotein in the intestine

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270005276204

Enhanced oral bioavailability of paclitaxel in mice treated with the P-glycoprotein blocker SDZ PSC 833.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270005276204

Expression of multidrug resistance-1 protein inversely correlates with paclitaxel response and survival in ovarian cancer patients: a study in serial samples

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270005276204

Genetic polymorphisms of the human MDR1 drug transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270005276204

Genetic polymorphisms of CYP2C8 in Japanese population.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270005276204

Frequency of single nucleotide polymorphisms in the P-glycoprotein drug transporter MDR1 gene in white subjects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270005276204

Identification of functionally variant MDR1 alleles among European Americans and African Americans

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270005276204

Polymorphisms in human CYP2C8 decrease metabolism of the anticancer drug paclitaxel and arachidonic acid.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270005276204

Non-synonymous single nucleotide alterations found in the CYP2C8 gene result in reduced in vitro paclitaxel metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270005276204

Five novel single nucleotide polymorphisms in the CYP2C8 gene, one of which induces a frame-shift.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270005276204

CYP3A4 gene polymorphisms influence testosterone 6beta-hydroxylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270005276204

Phase I trial, including pharmacokinetic and pharmacodynamic correlations, of combination paclitaxel and carboplatin in patients with metastatic non-small-cell lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270005276204

Polymorphism of the ABC transporter genes, MDR1, MRP1 and MRP2/cMOAT, in healthy Japanese subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270005276204

Functional polymorphisms of the human multidrug-resistance gene: multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270005276204

21 January 2018

Identifiers

DOI

10.1177/0091270005276204

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26 July 2017

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