(Q33396756)

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The Syk-kinase inhibitor R406 impairs platelet activation and monocyte tissue factor expression triggered by heparin-PF4 complex directed antibodies

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

The Syk-kinase inhibitor R406 impairs platelet activation and monocyte tissue factor expression triggered by heparin-PF4 complex directed antibodies (English)

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

1 reference

based on heuristic

inferred from title

Marie-Pierre Gratacap

1 reference

ORCID Public Data File 2021

author name string

T Lhermusier

1

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

J van Rottem

2

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

C Garcia

3

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

J-M Xuereb

4

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

A Ragab

5

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

V Martin

6

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

M-P Gratacap

7

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

P Sié

8

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

B Payrastre

9

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

publication date

1 October 2011

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

Journal of Thrombosis and Haemostasis

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Europe PubMed Central

PubMed publication ID

26 July 2017

9

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

10

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

2067-2076

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

Heparin-induced thrombocytopenia: a historical perspective

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2011.04470.X

21 January 2018

Thrombin generation and heparin-induced thrombocytopenia

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2011.04470.X

21 January 2018

Antibodies from patients with heparin-induced thrombocytopenia stimulate monocytic cells to express tissue factor and secrete interleukin-8.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2011.04470.X

21 January 2018

Induction of monocyte tissue factor expression by antibodies to heparin-platelet factor 4 complexes developed in heparin-induced thrombocytopenia.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2011.04470.X

21 January 2018

Monocyte-bound PF4 in the pathogenesis of heparin-induced thrombocytopenia

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2011.04470.X

21 January 2018

Immune endothelial-cell injury in heparin-associated thrombocytopenia

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2011.04470.X

21 January 2018

Heparin-induced thrombocytopenia/thrombosis in a transgenic mouse model requires human platelet factor 4 and platelet activation through FcgammaRIIA.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2011.04470.X

21 January 2018

Platelet integrins and immunoreceptors

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2011.04470.X

21 January 2018

A novel interaction between FlnA and Syk regulates platelet ITAM-mediated receptor signaling and function

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2011.04470.X

21 January 2018

Collagen receptor signalling in platelets: extending the role of the ITAM.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2011.04470.X

21 January 2018

GPVI and integrin alphaIIb beta3 signaling in platelets

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2011.04470.X

21 January 2018

The Fc receptor gamma-chain and the tyrosine kinase Syk are essential for activation of mouse platelets by collagen

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2011.04470.X

21 January 2018

The SYK tyrosine kinase: a crucial player in diverse biological functions

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2011.04470.X

21 January 2018

CLEC-2 activates Syk through dimerization

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2011.04470.X

21 January 2018

A new role for FcgammaRIIA in the potentiation of human platelet activation induced by weak stimulation

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2011.04470.X

21 January 2018

Coordinate interactions of Csk, Src, and Syk kinases with [alpha]IIb[beta]3 initiate integrin signaling to the cytoskeleton

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2011.04470.X

21 January 2018

Identification of FcgammaRIIa as the ITAM-bearing receptor mediating alphaIIbbeta3 outside-in integrin signaling in human platelets

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2011.04470.X

21 January 2018

Of mice and men: an open-label pilot study for treatment of immune thrombocytopenic purpura by an inhibitor of Syk.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2011.04470.X

21 January 2018

Spleen tyrosine kinases: biology, therapeutic targets and drugs

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2011.04470.X

21 January 2018

R406, an orally available spleen tyrosine kinase inhibitor blocks fc receptor signaling and reduces immune complex-mediated inflammation

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2011.04470.X

21 January 2018

PRT-060318, a novel Syk inhibitor, prevents heparin-induced thrombocytopenia and thrombosis in a transgenic mouse model

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2011.04470.X

21 January 2018

Evaluation of pretest clinical score (4 T's) for the diagnosis of heparin-induced thrombocytopenia in two clinical settings

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2011.04470.X

21 January 2018

Phosphatidylinositol 3,4,5-trisphosphate-dependent stimulation of phospholipase C-gamma2 is an early key event in FcgammaRIIA-mediated activation of human platelets.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2011.04470.X

21 January 2018

Standardization of platelet-derived microparticle enumeration by flow cytometry with calibrated beads: results of the International Society on Thrombosis and Haemostasis SSC Collaborative workshop.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2011.04470.X

21 January 2018

Flow cytometric analysis of tissue factor (TF) expression on stimulated monocytes--comparison to procoagulant activity of mononuclear blood cells.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2011.04470.X

21 January 2018

The novel Syk inhibitor R406 reveals mechanistic differences in the initiation of GPVI and CLEC-2 signaling in platelets.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2011.04470.X

21 January 2018

Roles of the C-terminal tyrosine residues of LAT in GPVI-induced platelet activation: insights into the mechanism of PLC gamma 2 activation

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2011.04470.X

21 January 2018

Heparin-induced thrombocytopenia and other immune thrombocytopenias: lessons from mouse models

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2011.04470.X

21 January 2018

The pathophysiology of immune-mediated heparin-induced thrombocytopenia

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2011.04470.X

21 January 2018

Insights from mouse models of heparin-induced thrombocytopenia and thrombosis

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2011.04470.X

21 January 2018

Treatment of rheumatoid arthritis with a Syk kinase inhibitor: a twelve-week, randomized, placebo-controlled trial

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2011.04470.X

21 January 2018

Tissue factor in cardiovascular diseases: molecular mechanisms and clinical implications

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2011.04470.X

21 January 2018

Eptifibatide-induced thrombocytopenia and thrombosis in humans require FcgammaRIIa and the integrin beta3 cytoplasmic domain

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2011.04470.X

21 January 2018

Eptifibatide-induced thrombocytopenia and thrombosis

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2011.04470.X

21 January 2018

Identifiers

10.1111/J.1538-7836.2011.04470.X

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

ResearchGate publication ID

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