(Q33408246)

26 July 2017

title

Kinetics of oxidation of benzphetamine by compounds I of cytochrome P450 2B4 and its mutants (English)

1 reference

26 July 2017

Xin Sheng

1

1 reference

26 July 2017

Haoming Zhang

2

1 reference

26 July 2017

Sang-Choul Im

3

1 reference

26 July 2017

John H Horner

4

1 reference

26 July 2017

Lucy Waskell

5

1 reference

26 July 2017

Paul F Hollenberg

6

1 reference

26 July 2017

Martin Newcomb

7

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26 July 2017

language of work or name

English

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publication date

1 March 2009

1 reference

Journal of the American Chemical Society

26 July 2017

published in

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26 July 2017

volume

131

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26 July 2017

issue

8

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26 July 2017

page(s)

2971-2976

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Spectra and kinetic studies of the compound I derivative of cytochrome P450 119.

26 July 2017

cites work

1 reference

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X-ray absorption spectroscopic characterization of a cytochrome P450 compound II derivative

21 June 2018

1 reference

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Photochemical production of a highly reactive porphyrin-iron-oxo species

21 June 2018

1 reference

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Cytochrome p450 compound I.

21 June 2018

1 reference

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Cytochrome P450 pharmacogenetics and cancer.

21 June 2018

1 reference

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Photochemical generation of a highly reactive iron-oxo intermediate. A true iron(V)-oxo species?

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2765530

Modulation of cytochrome P450 activity: implications for cancer therapy

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2765530

Formation of compound I by photo-oxidation of compound II.

21 June 2018

1 reference

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The discovery of the microsomal ethanol oxidizing system and its physiologic and pathologic role

21 June 2018

1 reference

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Hydroxylation by the hydroperoxy-iron species in cytochrome P450 enzymes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2765530

Multiple mechanisms and multiple oxidants in P450-catalyzed hydroxylations

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2765530

Heme-Containing Oxygenases

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2765530

Understanding thermostability in cytochrome P450 by combinatorial mutagenesis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2765530

Overexpression and purification of the membrane-bound cytochrome P450 2B4.

21 June 2018

1 reference

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Effects of a thiolate axial ligand on the pi-->pi* electronic states of oxoferryl porphyrins: a study of the optical and resonance Raman spectra of compounds I and II of chloroperoxidase.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2765530

Characterization of a cytochrome P450 from the acidothermophilic archaea Sulfolobus solfataricus

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2765530

Epoxidation of olefins by cytochrome P450: evidence from site-specific mutagenesis for hydroperoxo-iron as an electrophilic oxidant

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2765530

Cytochrome P450-catalyzed hydroxylation of hydrocarbons: kinetic deuterium isotope effects for the hydroxylation of an ultrafast radical clock.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2765530

The role of Thr268 in oxygen activation of cytochrome P450BM-3

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2765530

Uncoupling of the cytochrome P-450cam monooxygenase reaction by a single mutation, threonine-252 to alanine or valine: possible role of the hydroxy amino acid in oxygen activation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2765530

Peroxynitrite inactivation of human cytochrome P450s 2B6 and 2E1: heme modification and site-specific nitrotyrosine formation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2765530

Kinetic studies of reactions of iron(IV)-oxo porphyrin radical cations with organic reductants

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2765530

Spectroscopic characterization of the iron-oxo intermediate in cytochrome P450.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2765530

Crystallographic study on the dioxygen complex of wild-type and mutant cytochrome P450cam. Implications for the dioxygen activation mechanism

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2765530

Reaction of ferric cytochrome P450cam with peracids: kinetic characterization of intermediates on the reaction pathway

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2765530

Kinetic isotope effects implicate two electrophilic oxidants in cytochrome p450-catalyzed hydroxylations

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2765530

Epoxidation of olefins by hydroperoxo-ferric cytochrome P450.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2765530

Spectroscopic studies of peroxyacetic acid reaction intermediates of cytochrome P450cam and chloroperoxidase

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2765530

Replacement of active-site cysteine-436 by serine converts cytochrome P450 2B4 into an NADPH oxidase with negligible monooxygenase activity

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2765530

Phenylalanine 393 exerts thermodynamic control over the heme of flavocytochrome P450 BM3.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2765530

Hydroxylation of camphor by reduced oxy-cytochrome P450cam: mechanistic implications of EPR and ENDOR studies of catalytic intermediates in native and mutant enzymes

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2765530

Nitration and inactivation of cytochrome P450BM-3 by peroxynitrite. Stopped-flow measurements prove ferryl intermediates

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2765530

Cytochrome b5 increases the rate of product formation by cytochrome P450 2B4 and competes with cytochrome P450 reductase for a binding site on cytochrome P450 2B4

31 October 2018

1 reference

12 December 2020

Kinetic studies of the reaction of heme-thiolate enzyme chloroperoxidase with peroxynitrite

1 reference

12 December 2020

Synthesis of Peroxynitrite in a Two-Phase System Using Isoamyl Nitrite and Hydrogen Peroxide

1 reference

12 December 2020

Role of the alanine at position 363 of cytochrome P450 2B2 in influencing the NADPH- and hydroperoxide-supported activities

1 reference

12 December 2020

Peroxynitrite reaction with heme proteins

1 reference

12 December 2020

Role of hemoprotein P-450 in fatty acid omega-hydroxylation in a soluble enzyme system from liver microsomes

1 reference

12 December 2020

A role for threonine 302 in the mechanism-based inactivation of P450 2B4 by 2-ethynylnaphthalene

1 reference

12 December 2020

Evidence for compound I formation in the reaction of cytochrome P450cam with m-chloroperbenzoic acid

1 reference

12 December 2020

Spectrum of chloroperoxidase compound I

1 reference

12 December 2020

Identifiers

DOI

10.1021/JA808982G

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26 July 2017

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26 July 2017

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