(Q33411165)

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The abnormal proplatelet formation in MYH9-related macrothrombocytopenia results from an increased actomyosin contractility and is rescued by myosin IIA inhibition.

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scholarly article

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28 February 2020

The abnormal proplatelet formation in MYH9-related macrothrombocytopenia results from an increased actomyosin contractility and is rescued by myosin IIA inhibition (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24165359%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Giant platelet disorder

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based on heuristic

inferred from title

8

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28 February 2020

William Vainchenker

9

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28 February 2020

Martial Balland

10

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28 February 2020

author name string

Y Chen

1

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28 February 2020

S Boukour

2

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28 February 2020

R Milloud

3

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28 February 2020

R Favier

4

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28 February 2020

B Saposnik

5

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28 February 2020

N Schlegel

6

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28 February 2020

A Nurden

7

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28 February 2020

P Nurden

11

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28 February 2020

N Debili

12

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28 February 2020

publication date

1 December 2013

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28 February 2020

number of pages

13

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Journal of Thrombosis and Haemostasis

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28 February 2020

11

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28 February 2020

12

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28 February 2020

2163-2175

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28 February 2020

Regulation of megakaryocyte maturation and platelet formation.

1 reference

https://api.crossref.org/works/10.1111%2FJTH.12436

21 January 2018

Mechanics of proplatelet elaboration

1 reference

https://api.crossref.org/works/10.1111%2FJTH.12436

21 January 2018

Blood platelets are assembled principally at the ends of proplatelet processes produced by differentiated megakaryocytes

1 reference

https://api.crossref.org/works/10.1111%2FJTH.12436

21 January 2018

The May-Hegglin anomaly gene MYH9 is a negative regulator of platelet biogenesis modulated by the Rho-ROCK pathway

1 reference

https://api.crossref.org/works/10.1111%2FJTH.12436

21 January 2018

Mutations responsible for MYH9-related thrombocytopenia impair SDF-1-driven migration of megakaryoblastic cells

1 reference

https://api.crossref.org/works/10.1111%2FJTH.12436

21 January 2018

Characterization of the megakaryocyte demarcation membrane system and its role in thrombopoiesis

1 reference

https://api.crossref.org/works/10.1111%2FJTH.12436

21 January 2018

Microtubule and cortical forces determine platelet size during vascular platelet production

1 reference

https://api.crossref.org/works/10.1111%2FJTH.12436

21 January 2018

RUNX1-induced silencing of non-muscle myosin heavy chain IIB contributes to megakaryocyte polyploidization

1 reference

https://api.crossref.org/works/10.1111%2FJTH.12436

21 January 2018

Myosin-II inhibition and soft 2D matrix maximize multinucleation and cellular projections typical of platelet-producing megakaryocytes

1 reference

https://api.crossref.org/works/10.1111%2FJTH.12436

21 January 2018

Mutation of MYH9, encoding non-muscle myosin heavy chain A, in May-Hegglin anomaly.

1 reference

https://api.crossref.org/works/10.1111%2FJTH.12436

21 January 2018

Mutations in MYH9 result in the May-Hegglin anomaly, and Fechtner and Sebastian syndromes. The May-Heggllin/Fechtner Syndrome Consortium

1 reference

https://api.crossref.org/works/10.1111%2FJTH.12436

21 January 2018

MYH9-related platelet disorders

1 reference

https://api.crossref.org/works/10.1111%2FJTH.12436

21 January 2018

Advances in the understanding of MYH9 disorders

1 reference

https://api.crossref.org/works/10.1111%2FJTH.12436

21 January 2018

Recent advances in the understanding and management of MYH9-related inherited thrombocytopenias

1 reference

https://api.crossref.org/works/10.1111%2FJTH.12436

21 January 2018

Position of nonmuscle myosin heavy chain IIA (NMMHC-IIA) mutations predicts the natural history of MYH9-related disease

1 reference

https://api.crossref.org/works/10.1111%2FJTH.12436

21 January 2018

Abnormal megakaryocyte morphology and proplatelet formation in mice with megakaryocyte-restricted MYH9 inactivation.

1 reference

https://api.crossref.org/works/10.1111%2FJTH.12436

21 January 2018

Megakaryocyte-restricted MYH9 inactivation dramatically affects hemostasis while preserving platelet aggregation and secretion.

1 reference

https://api.crossref.org/works/10.1111%2FJTH.12436

21 January 2018

An MYH9 human disease model in flies: site-directed mutagenesis of the Drosophila non-muscle myosin II results in hypomorphic alleles with dominant character.

1 reference

https://api.crossref.org/works/10.1111%2FJTH.12436

21 January 2018

Mouse models of MYH9-related disease: mutations in nonmuscle myosin II-A.

1 reference

https://api.crossref.org/works/10.1111%2FJTH.12436

21 January 2018

MAL/SRF complex is involved in platelet formation and megakaryocyte migration by regulating MYL9 (MLC2) and MMP9.

1 reference

https://api.crossref.org/works/10.1111%2FJTH.12436

21 January 2018

Enucleation of human erythroblasts involves non-muscle myosin IIB.

1 reference

https://api.crossref.org/works/10.1111%2FJTH.12436

21 January 2018

Matrix elasticity directs stem cell lineage specification

1 reference

https://api.crossref.org/works/10.1111%2FJTH.12436

21 January 2018

A new micropatterning method of soft substrates reveals that different tumorigenic signals can promote or reduce cell contraction levels.

1 reference

https://api.crossref.org/works/10.1111%2FJTH.12436

21 January 2018

Mutations in human nonmuscle myosin IIA found in patients with May-Hegglin anomaly and Fechtner syndrome result in impaired enzymatic function

1 reference

https://api.crossref.org/works/10.1111%2FJTH.12436

21 January 2018

Multiple regulatory steps control mammalian nonmuscle myosin II assembly in live cells

1 reference

https://api.crossref.org/works/10.1111%2FJTH.12436

21 January 2018

Proplatelet formation deficit and megakaryocyte death contribute to thrombocytopenia in Myh9 knockout mice.

1 reference

https://api.crossref.org/works/10.1111%2FJTH.12436

21 January 2018

Cell shape provides global control of focal adhesion assembly

1 reference

https://api.crossref.org/works/10.1111%2FJTH.12436

21 January 2018

Nonmuscle myosin IIA-dependent force inhibits cell spreading and drives F-actin flow

1 reference

https://api.crossref.org/works/10.1111%2FJTH.12436

21 January 2018

May-Hegglin anomaly: a defect in megakaryocyte fragmentation?

1 reference

https://api.crossref.org/works/10.1111%2FJTH.12436

21 January 2018

MYH9related disease: four novel mutations of the tail domain of myosin-9 correlating with a mild clinical phenotype

1 reference

https://api.crossref.org/works/10.1111%2FJTH.12436

21 January 2018

Proplatelet formation is regulated by the Rho/ROCK pathway

1 reference

https://api.crossref.org/works/10.1111%2FJTH.12436

21 January 2018

Identifiers

10.1111/JTH.12436

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24165359%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

1 reference

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28 February 2020

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