(Q33414617)

26 July 2017

title

Impaired hematopoietic differentiation of RUNX1-mutated induced pluripotent stem cells derived from FPD/AML patients (English)

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26 July 2017

M Sakurai

1

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26 July 2017

H Kunimoto

2

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26 July 2017

N Watanabe

3

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26 July 2017

Y Fukuchi

4

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26 July 2017

S Yuasa

5

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26 July 2017

S Yamazaki

6

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26 July 2017

T Nishimura

7

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26 July 2017

K Sadahira

8

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26 July 2017

K Fukuda

9

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26 July 2017

H Okano

10

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26 July 2017

H Nakauchi

11

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26 July 2017

Y Morita

12

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26 July 2017

I Matsumura

13

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26 July 2017

K Kudo

14

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26 July 2017

E Ito

15

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26 July 2017

Y Ebihara

16

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26 July 2017

K Tsuji

17

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26 July 2017

Y Harada

18

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26 July 2017

H Harada

19

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26 July 2017

S Okamoto

20

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26 July 2017

H Nakajima

21

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26 July 2017

publication date

15 April 2014

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26 July 2017

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26 July 2017

volume

28

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26 July 2017

issue

12

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26 July 2017

page(s)

2344-2354

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AML-1 is required for megakaryocytic maturation and lymphocytic differentiation, but not for maintenance of hematopoietic stem cells in adult hematopoiesis

26 July 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2014.136

Point mutations in the RUNX1/AML1 gene: another actor in RUNX leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2014.136

High incidence of somatic mutations in the AML1/RUNX1 gene in myelodysplastic syndrome and low blast percentage myeloid leukemia with myelodysplasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2014.136

Mutations of AML1 are common in therapy-related myelodysplasia following therapy with alkylating agents and are significantly associated with deletion or loss of chromosome arm 7q and with subsequent leukemic transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2014.136

High frequency of AML1/RUNX1 point mutations in radiation-associated myelodysplastic syndrome around Semipalatinsk nuclear test site

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2014.136

RUNX1 mutations are frequent in chronic myelomonocytic leukemia and mutations at the C-terminal region might predict acute myeloid leukemia transformation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2014.136

Transcription factor mutations in myelodysplastic/myeloproliferative neoplasms

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2014.136

Disease mutations in RUNX1 and RUNX2 create nonfunctional, dominant-negative, or hypomorphic alleles.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2014.136

Molecular pathways mediating MDS/AML with focus on AML1/RUNX1 point mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2014.136

In vitro analyses of known and novel RUNX1/AML1 mutations in dominant familial platelet disorder with predisposition to acute myelogenous leukemia: implications for mechanisms of pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2014.136

Haploinsufficiency of CBFA2 causes familial thrombocytopenia with propensity to develop acute myelogenous leukaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2014.136

Expression of a conditional AML1-ETO oncogene bypasses embryonic lethality and establishes a murine model of human t(8;21) acute myeloid leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2014.136

Stem cell exhaustion due to Runx1 deficiency is prevented by Evi5 activation in leukemogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2014.136

Induction of pluripotent stem cells from adult human fibroblasts by defined factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2014.136

Induced pluripotent stem cell lines derived from human somatic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2014.136

Trisomy 21-associated defects in human primitive hematopoiesis revealed through induced pluripotent stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2014.136

Human-induced pluripotent stem cells from blood cells of healthy donors and patients with acquired blood disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2014.136

Disease-specific induced pluripotent stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2014.136

Wnt3a stimulates maturation of impaired neutrophils developed from severe congenital neutropenia patient-derived pluripotent stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2014.136

Altered hematopoiesis in trisomy 21 as revealed through in vitro differentiation of isogenic human pluripotent cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2014.136

Zinc-finger nuclease-mediated correction of α-thalassemia in iPS cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2014.136

Generation of iPSCs from cultured human malignant cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2014.136

Patient-derived induced pluripotent stem cells recapitulate hematopoietic abnormalities of juvenile myelomonocytic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2014.136

Generation of induced pluripotent stem cells from a small amount of human peripheral blood using a combination of activated T cells and Sendai virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2014.136

Comprehensive analysis of myeloid lineage conversion using mice expressing an inducible form of C/EBP alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2014.136

Generation of functional erythrocytes from human embryonic stem cell-derived definitive hematopoiesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2014.136

TIMP-3 recruits quiescent hematopoietic stem cells into active cell cycle and expands multipotent progenitor pool

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2014.136

Generation of induced pluripotent stem cells from human terminally differentiated circulating T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2014.136

Leukosialin (CD43) defines hematopoietic progenitors in human embryonic stem cell differentiation cultures

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2014.136

Definitive hematopoiesis requires Runx1 C-terminal-mediated subnuclear targeting and transactivation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2014.136

AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2014.136

Disruption of the Cbfa2 gene causes necrosis and hemorrhaging in the central nervous system and blocks definitive hematopoiesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2014.136

Runx1 expression marks long-term repopulating hematopoietic stem cells in the midgestation mouse embryo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2014.136

The haemangioblast generates haematopoietic cells through a haemogenic endothelium stage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2014.136

Runx1 is required for the endothelial to haematopoietic cell transition but not thereafter

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2014.136

RUNX1a enhances hematopoietic lineage commitment from human embryonic stem cells and inducible pluripotent stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2014.136

Novel method for efficient production of multipotential hematopoietic progenitors from human embryonic stem cells

21 January 2018

1 reference

12 December 2020

Hematopoietic and endothelial differentiation of human induced pluripotent stem cells

1 reference

12 December 2020

Implications of somatic mutations in the AML1 gene in radiation-associated and therapy-related myelodysplastic syndrome/acute myeloid leukemia

1 reference

12 December 2020

Generation of induced pluripotent stem cells from primary chronic myelogenous leukemia patient samples

1 reference

12 December 2020

Mutations of the AML1 gene in myelodysplastic syndrome and their functional implications in leukemogenesis

1 reference

12 December 2020

Generation of functional platelets from human embryonic stem cells in vitro via ES-sacs, VEGF-promoted structures that concentrate hematopoietic progenitors

1 reference

12 December 2020

Cbfa2 is required for the formation of intra-aortic hematopoietic clusters.

1 reference

12 December 2020

Runx1 protects hematopoietic stem/progenitor cells from oncogenic insult

1 reference

12 December 2020

Stimulation of mouse and human primitive hematopoiesis by murine embryonic aorta-gonad-mesonephros-derived stromal cell lines.

1 reference

12 December 2020

Identifiers

DOI

10.1038/LEU.2014.136

1 reference

Dimensions Publication ID

26 July 2017

1023297970

0 references

1 reference