(Q33418209)

26 July 2017

Neutral cysteine protease bleomycin hydrolase is essential for the breakdown of deiminated filaggrin into amino acids (English)

1 reference

26 July 2017

Yayoi Kamata

1

1 reference

26 July 2017

Aya Taniguchi

2

1 reference

26 July 2017

Mami Yamamoto

3

1 reference

26 July 2017

Junko Nomura

4

1 reference

26 July 2017

Kazuhiko Ishihara

5

1 reference

26 July 2017

Hidenari Takahara

6

1 reference

26 July 2017

Toshihiko Hibino

7

1 reference

26 July 2017

Atsushi Takeda

8

1 reference

26 July 2017

language of work or name

English

0 references

publication date

13 March 2009

1 reference

Journal of Biological Chemistry

26 July 2017

1 reference

26 July 2017

284

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26 July 2017

12829-12836

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26 July 2017

19

1 reference

describes a project that uses

26 July 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2676013/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Caspase-14 reveals its secrets

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2676013

The filaggrin story: novel insights into skin-barrier function and disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2676013

Skin hydration: a review on its molecular mechanisms

21 June 2018

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Caspase-14 protects against epidermal UVB photodamage and water loss

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2676013

Quantification of neutral cysteine protease bleomycin hydrolase and its localization in rat tissues

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2676013

Peptidylarginine deiminases and deimination in biology and pathology: relevance to skin homeostasis.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2676013

Protective mechanisms against homocysteine toxicity: the role of bleomycin hydrolase.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2676013

Processing of amyloid beta-peptides by neutral cysteine protease bleomycin hydrolase

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2676013

The peptidylarginine deiminases expressed in human epidermis differ in their substrate specificities and subcellular locations.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2676013

The epidermal barrier function is dependent on the serine protease CAP1/Prss8

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2676013

Moisturization and skin barrier function

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2676013

Loss of proteolytically processed filaggrin caused by epidermal deletion of Matriptase/MT-SP1.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2676013

PAD, a growing family of citrullinating enzymes: genes, features and involvement in disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2676013

Human peptidylarginine deiminase type III: molecular cloning and nucleotide sequence of the cDNA, properties of the recombinant enzyme, and immunohistochemical localization in human skin

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2676013

Two new proteases in the MHC class I processing pathway

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2676013

Human bleomycin hydrolase regulates the secretion of amyloid precursor protein

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2676013

Human bleomycin hydrolase binds ribosomal proteins

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2676013

Immunohistochemical localization of the neutral cysteine protease bleomycin hydrolase in human skin

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2676013

The neutral cysteine protease bleomycin hydrolase is essential for epidermal integrity and bleomycin resistance

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2676013

An evolutionarily conserved cysteine protease, human bleomycin hydrolase, binds to the human homologue of ubiquitin-conjugating enzyme 9

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2676013

The role of tricorn protease and its aminopeptidase-interacting factors in cellular protein degradation.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2676013

Protein unfolding by peptidylarginine deiminase. Substrate specificity and structural relationships of the natural substrates trichohyalin and filaggrin

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2676013

Purification and characterization of bleomycin hydrolase, which represents a new family of cysteine proteases, from rat skin

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2676013

Cloning and analysis of cDNA encoding rat bleomycin hydrolase, a DNA-binding cysteine protease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2676013

Preferential deimination of keratin K1 and filaggrin during the terminal differentiation of human epidermis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2676013

Vitamin D, calcium, and epidermal differentiation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2676013

Independent regulation of two cytoplasmic processing stages of the intermediate filament-associated protein filaggrin and role of Ca2+ in the second stage.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2676013

Involucrin--structure and role in envelope assembly

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2676013

The structure of human trichohyalin. Potential multiple roles as a functional EF-hand-like calcium-binding protein, a cornified cell envelope precursor, and an intermediate filament-associated (cross-linking) protein

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2676013

The proteins elafin, filaggrin, keratin intermediate filaments, loricrin, and small proline-rich proteins 1 and 2 are isodipeptide cross-linked components of the human epidermal cornified cell envelope

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2676013

Histidine-rich proteins (filaggrins): Structural and functional heterogeneity during epidermal differentiation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2676013

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2676013

Filaggrin breakdown to water binding compounds during development of the rat stratum corneum is controlled by the water activity of the environment.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2676013

Terminal differentiation of epidermal keratinocytes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2676013

Molecular biology of keratinocyte differentiation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2676013

Filaggrin: a keratin filament associated protein

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2676013

Elafin: an elastase-specific inhibitor of human skin. Purification, characterization, and complete amino acid sequence

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2676013

Characterization of human loricrin. Structure and function of a new class of epidermal cell envelope proteins

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2676013

Stratum corneum moisturization at the molecular level.

21 June 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807908200

Proprotein convertase expression and localization in epidermis: evidence for multiple roles and substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807908200

Double-layer fluorescent zymography for processing protease detection

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807908200

Bleomycin hydrolase (Blh1p), a multi-sited thiol protease in search of a distinct physiological role.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807908200

Histidine-rich protein of the keratohyalin granules. Source of the free amino acids, urocanic acid and pyrrolidone carboxylic acid in the stratum corneum.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807908200

Formation of the epidermal calcium gradient coincides with key milestones of barrier ontogenesis in the rodent

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M807908200

Filaggrin linker segment peptide and cystatin alpha are parts of a complex of the cornified envelope of epidermis

21 January 2018

1 reference

12 December 2020

Identification of proteolytic cleavage sites in the conversion of profilaggrin to filaggrin in mammalian epidermis

1 reference

12 December 2020

Characterization of profilaggrin endoproteinase 1. A regulated cytoplasmic endoproteinase of epidermis

1 reference

12 December 2020

Alignment/phylogeny of the papain superfamily of cysteine proteases.

1 reference

12 December 2020

Cytoplasmic processing of human profilaggrin by active mu-calpain

1 reference

12 December 2020

Expression of mouse uterine peptidylarginine deiminase in Escherichia coli: construction of expression plasmid and properties of the recombinant enzyme

1 reference

12 December 2020

Loss of normal profilaggrin and filaggrin in flaky tail (ft/ft) mice: an animal model for the filaggrin-deficient skin disease ichthyosis vulgaris

1 reference

12 December 2020

Evidence for specific proteolytic cleavage of the N-terminal domain of human profilaggrin during epidermal differentiation

1 reference

12 December 2020

Pyrrolidone carboxylic acid and the skin

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M807908200

1 reference

26 July 2017

1 reference

26 July 2017

1 reference