(Q33424935)

26 July 2017

title

Direct cocktail analysis of drug discovery compounds in pooled plasma samples using liquid chromatography-tandem mass spectrometry (English)

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liquid chromatography-tandem mass spectrometry

26 July 2017

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Yunsheng Hsieh

1

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26 July 2017

Matthew S Bryant

2

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26 July 2017

Jean-Marc Brisson

3

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26 July 2017

Kwokei Ng

4

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26 July 2017

Walter A Korfmacher

5

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26 July 2017

publication date

1 February 2002

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Journal of Chromatography B Analytical Technologies in the Biomedical and Life Sciences

26 July 2017

published in

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26 July 2017

volume

767

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26 July 2017

issue

2

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26 July 2017

page(s)

353-362

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describes a project that uses

26 July 2017

liquid chromatography-tandem mass spectrometry

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High-throughput screening in drug metabolism and pharmacokinetic support of drug discovery

inferred from title

cites work

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7 January 2021

Direct plasma sample injection in multiple-component LC-MS-MS assays for high-throughput pharmacokinetic screening.

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7 January 2021

In vivo pharmacokinetic screening in cassette dosing experiments; the use of on-line Pprospekt liquid chromatography/atmospheric pressure chemical ionization tandem mass spectrometry technology in drug discovery

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7 January 2021

Use of "N-in-One" dosing to create an in vivo pharmacokinetics database for use in developing structure-pharmacokinetic relationships

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7 January 2021

High-throughput caco-2 cell permeability screening by cassette dosing and sample pooling approaches using direct injection/on-line guard cartridge extraction/tandem mass spectrometry

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https://api.crossref.org/works/10.1016%2FS1570-0232%2801%2900608-0

7 January 2021

The simultaneous determination of mixtures of drug candidates by liquid chromatography/atmospheric pressure chemical ionization mass spectrometry as an in vivo drug screening procedure

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7 January 2021

Demonstration of the capabilities of a parallel high performance liquid chromatography tandem mass spectrometry system for use in the analysis of drug discovery plasma samples

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https://api.crossref.org/works/10.1016%2FS1570-0232%2801%2900608-0

7 January 2021

Sample pooling to expedite bioanalysis and pharmacokinetic research

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7 January 2021

The use of high-flow high performance liquid chromatography coupled with positive and negative ion electrospray tandem mass spectrometry for quantitative bioanalysis via direct injection of the plasma/serum samples

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https://api.crossref.org/works/10.1016%2FS1570-0232%2801%2900608-0

7 January 2021

Direct determination of bisphenol A and nonylphenol in river water by column-switching semi-microcolumn liquid chromatography/electrospray mass spectrometry

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https://api.crossref.org/works/10.1016%2FS1570-0232%2801%2900608-0

7 January 2021

Direct injection versus liquid-liquid extraction for plasma sample analysis by high performance liquid chromatography with tandem mass spectrometry

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7 January 2021

Automated sample preparation for the determination of budesonide in plasma samples by liquid chromatography and tandem mass spectrometry

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https://api.crossref.org/works/10.1016%2FS1570-0232%2801%2900608-0

7 January 2021

Direct analysis of plasma samples for drug discovery compounds using mixed-function column liquid chromatography tandem mass spectrometry

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7 January 2021

Quantitative screening and matrix effect studies of drug discovery compounds in monkey plasma using fast-gradient liquid chromatography/tandem mass spectrometry

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2801%2900608-0

7 January 2021

Direct simultaneous analysis of plasma samples for a drug discovery compound and its hydroxyl metabolite using mixed-function column liquid chromatography-tandem mass spectrometry

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2801%2900608-0

7 January 2021

Matrix effect in quantitative LC/MS/MS analyses of biological fluids: a method for determination of finasteride in human plasma at picogram per milliliter concentrations

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2801%2900608-0

7 January 2021

Bioanalytical high-throughput selected reaction monitoring-LC/MS determination of selected estrogen receptor modulators in human plasma: 2000 samples/day

1 reference

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7 January 2021

Liquid-liquid extraction in the 96-well plate format with SRM LC/MS quantitative determination of methotrexate and its major metabolite in human plasma

1 reference

https://api.crossref.org/works/10.1016%2FS1570-0232%2801%2900608-0

7 January 2021

10.1016/S1570-0232(01)00608-0

Identifiers

DOI

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26 July 2017

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