(Q33435117)

26 July 2017

title

Histones link inflammation and thrombosis through the induction of Weibel-Palade body exocytosis (English)

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26 July 2017

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A Michels

1

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26 July 2017

S Albánez

2

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J Mewburn

3

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26 July 2017

K Nesbitt

4

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T J Gould

5

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P C Liaw

6

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P D James

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L L Swystun

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26 July 2017

D Lillicrap

9

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26 July 2017

publication date

2 September 2016

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Journal of Thrombosis and Haemostasis

26 July 2017

published in

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26 July 2017

volume

14

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26 July 2017

issue

11

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26 July 2017

page(s)

2274-2286

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Neutrophil extracellular traps: double-edged swords of innate immunity

26 July 2017

cites work

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Extracellular DNA traps promote thrombosis.

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The effectors of innate immunity: DAMPs, DAMEs, or DIMEs?

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Role of pattern-recognition receptors in cardiovascular health and disease

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Activation of the human contact system on neutrophil extracellular traps.

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Extracellular histones increase plasma thrombin generation by impairing thrombomodulin-dependent protein C activation.

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Extracellular histones promote thrombin generation through platelet-dependent mechanisms: involvement of platelet TLR2 and TLR4

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Mechanical stability and fibrinolytic resistance of clots containing fibrin, DNA, and histones.

21 January 2018

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Extracellular histones induce tissue factor expression in vascular endothelial cells via TLR and activation of NF-κB and AP-1.

21 January 2018

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Hypoxia-induced exocytosis of endothelial cell Weibel-Palade bodies. A mechanism for rapid neutrophil recruitment after cardiac preservation

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Binding of the von Willebrand factor A1 domain to histone.

21 January 2018

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Histones induce rapid and profound thrombocytopenia in mice

21 January 2018

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Neutrophil extracellular traps promote deep vein thrombosis in mice

21 January 2018

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Extracellular histones are major mediators of death in sepsis

21 January 2018

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In vivo imaging visualizes discoid platelet aggregations without endothelium disruption and implicates contribution of inflammatory cytokine and integrin signaling

21 January 2018

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P2X1 expressed on polymorphonuclear neutrophils and platelets is required for thrombosis in mice

21 January 2018

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Endothelial von Willebrand factor regulates angiogenesis

21 January 2018

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Platelets adhered to endothelial cell-bound ultra-large von Willebrand factor strings support leukocyte tethering and rolling under high shear stress

21 January 2018

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Aging and ABO blood type influence von Willebrand factor and factor VIII levels through interrelated mechanisms.

21 January 2018

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Prognostic utility and characterization of cell-free DNA in patients with severe sepsis

21 January 2018

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Use of a mouse model to elucidate the phenotypic effects of the von Willebrand factor cleavage mutants, Y1605A/M1606A and R1597W.

21 January 2018

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Cancers predispose neutrophils to release extracellular DNA traps that contribute to cancer-associated thrombosis

21 January 2018

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Differential regulation of endothelial exocytosis of P-selectin and von Willebrand factor by protease-activated receptors and cAMP

21 January 2018

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Formation of platelet-binding von Willebrand factor strings on non-endothelial cells.

21 January 2018

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Circulating histones are mediators of trauma-associated lung injury.

21 January 2018

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Fluvastatin inhibits regulated secretion of endothelial cell von Willebrand factor in response to diverse secretagogues

21 January 2018

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Protective anti-inflammatory effect of ADAMTS13 on myocardial ischemia/reperfusion injury in mice

21 January 2018

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Leukocyte rolling and extravasation are severely compromised in P selectin-deficient mice

21 January 2018

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Angiopoietin 2 mediates microvascular and hemodynamic alterations in sepsis

21 January 2018

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Inter-α inhibitor protein and its associated glycosaminoglycans protect against histone-induced injury

21 January 2018

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Unwinding the von Willebrand factor strings puzzle

21 January 2018

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Circulating DNA and myeloperoxidase indicate disease activity in patients with thrombotic microangiopathies

21 January 2018

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Molecular inflammation: underpinnings of aging and age-related diseases

21 January 2018

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Aging is associated with quantitative and qualitative changes in circulating cell-free DNA: the Vitality 90+ study.

21 January 2018

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Von Willebrand factor regulation in patients with acute and chronic cerebrovascular disease: a pilot, case-control study.

21 January 2018

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Genetic variation associated with plasma von Willebrand factor levels and the risk of incident venous thrombosis

21 January 2018

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Elevated circulating E-selectin, intercellular adhesion molecule 1, and von Willebrand factor in patients with severe infection

21 January 2018

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Prednisolone dose-dependently influences inflammation and coagulation during human endotoxemia.

21 January 2018

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Potent irreversible P2Y12 inhibition does not reduce LPS-induced coagulation activation in a randomized, double-blind, placebo-controlled trial

21 January 2018

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von Willebrand factor promotes leukocyte extravasation

21 January 2018

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21 January 2018

Identifiers

DOI

10.1111/JTH.13493

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26 July 2017

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