(Q33449510)

English

Directed evolution of a secretory leader for the improved expression of heterologous proteins and full-length antibodies in Saccharomyces cerevisiae

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scholarly article

1 reference

Europe PubMed Central

26 July 2017

Directed evolution of a secretory leader for the improved expression of heterologous proteins and full-length antibodies in Saccharomyces cerevisiae (English)

1 reference

Europe PubMed Central

26 July 2017

Saccharomyces cerevisiae

0 references

directed evolution

0 references

protein evolution

0 references

1 reference

based on heuristic

inferred from title

author name string

J Andy Rakestraw

1

1 reference

Europe PubMed Central

26 July 2017

Stephen L Sazinsky

2

1 reference

Europe PubMed Central

26 July 2017

Andrea Piatesi

3

1 reference

Europe PubMed Central

26 July 2017

Eugene Antipov

4

1 reference

Europe PubMed Central

26 July 2017

K Dane Wittrup

5

1 reference

Europe PubMed Central

26 July 2017

publication date

1 August 2009

1 reference

Europe PubMed Central

26 July 2017

Biotechnology and Bioengineering

1 reference

Europe PubMed Central

26 July 2017

103

1 reference

Europe PubMed Central

26 July 2017

6

1 reference

Europe PubMed Central

26 July 2017

1192-1201

1 reference

Europe PubMed Central

26 July 2017

Isolation and characterization of human antibodies targeting human aspartyl (asparaginyl) beta-hydroxylase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847895

21 June 2018

Selection of horseradish peroxidase variants with enhanced enantioselectivity by yeast surface display.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847895

21 June 2018

Isolation of engineered, full-length antibodies from libraries expressed in Escherichia coli

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847895

21 June 2018

Antibody production with yeasts and filamentous fungi: on the road to large scale?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847895

21 June 2018

A flow cytometric assay for screening improved heterologous protein secretion in yeast

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847895

21 June 2018

High-affinity CD25-binding IL-2 mutants potently stimulate persistent T cell growth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847895

21 June 2018

Protein transport from the late Golgi to the vacuole in the yeast Saccharomyces cerevisiae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847895

21 June 2018

Directed evolution of an anti-carcinoembryonic antigen scFv with a 4-day monovalent dissociation half-time at 37 degrees C.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847895

21 June 2018

Degradation of mutated bovine pancreatic trypsin inhibitor in the yeast vacuole suggests post-endoplasmic reticulum protein quality control

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847895

21 June 2018

Quality control in the endoplasmic reticulum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847895

21 June 2018

Intracellular trafficking and metabolic turnover of yeast prepro-alpha-factor-SRIF precursors in GH3 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847895

21 June 2018

An ER membrane protein, Sop4, facilitates ER export of the yeast plasma membrane [H+]ATPase, Pma1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847895

21 June 2018

A subset of yeast vacuolar protein sorting mutants is blocked in one branch of the exocytic pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847895

21 June 2018

Directed evolution of antibody fragments with monovalent femtomolar antigen-binding affinity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847895

21 June 2018

Human lysozyme secretion increased by alpha-factor pro-sequence in Pichia pastoris

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847895

21 June 2018

Increasing the secretory capacity of Saccharomyces cerevisiae for production of single-chain antibody fragments.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847895

21 June 2018

Novel Golgi to vacuole delivery pathway in yeast: identification of a sorting determinant and required transport component.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847895

21 June 2018

Protein transport across the eukaryotic endoplasmic reticulum and bacterial inner membranes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847895

21 June 2018

Der1, a novel protein specifically required for endoplasmic reticulum degradation in yeast

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847895

21 June 2018

Analysis and sorting of live cells according to secreted molecules, relocated to a cell-surface affinity matrix

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847895

21 June 2018

New heterologous modules for classical or PCR-based gene disruptions in Saccharomyces cerevisiae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847895

21 June 2018

Parallel secretory pathways to the cell surface in yeast

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847895

21 June 2018

Alpha-factor-directed synthesis and secretion of mature foreign proteins in Saccharomyces cerevisiae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847895

21 June 2018

In vitro cultivation of human tumors: establishment of cell lines derived from a series of solid tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847895

21 June 2018

Secretion of functional antibody and Fab fragment from yeast cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847895

21 June 2018

Glycosylation and structure of the yeast MF alpha 1 alpha-factor precursor is important for efficient transport through the secretory pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847895

21 June 2018

The pro-region of the yeast prepro-alpha-factor is essential for membrane translocation of human insulin-like growth factor 1 in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847895

21 June 2018

Directed evolution of the epidermal growth factor receptor extracellular domain for expression in yeast.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847895

31 October 2018

Contrasting secretory processing of simultaneously expressed heterologous proteins in Saccharomyces cerevisiae.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847895

31 October 2018

Comparison of different signal peptides for secretion of heterologous proteins in fission yeast.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847895

31 October 2018

Substantial energetic improvement with minimal structural perturbation in a high affinity mutant antibody

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847895

31 October 2018

Engineering antibody affinity by yeast surface display.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847895

31 October 2018

Gene disruption.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847895

31 October 2018

Expression of full-length immunoglobulins in Escherichia coli: rapid and efficient production of aglycosylated antibodies.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847895

31 October 2018

Intracellular retention of newly synthesized insulin in yeast is caused by endoproteolytic processing in the Golgi complex

1 reference

https://pubmed.ncbi.nlm.nih.gov/19459139

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alpha-factor-leader-directed secretion of recombinant human-insulin-like growth factor I from Saccharomyces cerevisiae. Precursor formation and processing in the yeast secretory pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/19459139

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Secretion of human epidermal growth factor from Saccharomyces cerevisiae using synthetic leader sequences.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19459139

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein disulfide isomerase overexpression increases secretion of foreign proteins in Saccharomyces cerevisiae

1 reference

https://pubmed.ncbi.nlm.nih.gov/19459139

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synthetic leaders with potential BiP binding mediate high-yield secretion of correctly folded insulin precursors from Saccharomyces cerevisiae

1 reference

https://pubmed.ncbi.nlm.nih.gov/19459139

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sorting signals can direct receptor-mediated export of soluble proteins into COPII vesicles

1 reference

https://pubmed.ncbi.nlm.nih.gov/19459139

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1002/BIT.22338

1 reference

Europe PubMed Central

26 July 2017

1 reference

Europe PubMed Central

26 July 2017

1 reference

Europe PubMed Central

26 July 2017

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