(Q33496139)

27 July 2017

Highly efficient differentiation and enrichment of spinal motor neurons derived from human and monkey embryonic stem cells (English)

1 reference

27 July 2017

Tamaki Wada

1

1 reference

27 July 2017

Makoto Honda

2

1 reference

27 July 2017

Itsunari Minami

3

1 reference

27 July 2017

Norie Tooi

4

1 reference

27 July 2017

Yuji Amagai

5

1 reference

27 July 2017

Norio Nakatsuji

6

1 reference

27 July 2017

Kazuhiro Aiba

7

1 reference

27 July 2017

language of work or name

English

0 references

publication date

24 August 2009

1 reference

27 July 2017

1 reference

27 July 2017

4

1 reference

27 July 2017

8

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27 July 2017

e6722

1 reference

Creative Commons Attribution 4.0 International

27 July 2017

start time

24 August 2009

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Stem cell-based cell therapy in neurological diseases: a review

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726947

Human embryonic stem cell-derived motor neurons expressing SOD1 mutants exhibit typical signs of motor neuron degeneration linked to ALS.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726947

Induced pluripotent stem cells from a spinal muscular atrophy patient

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726947

Non-cell-autonomous effect of human SOD1 G37R astrocytes on motor neurons derived from human embryonic stem cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726947

Human embryonic stem cell-derived motor neurons are sensitive to the toxic effect of glial cells carrying an ALS-causing mutation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726947

Dorsomorphin, a selective small molecule inhibitor of BMP signaling, promotes cardiomyogenesis in embryonic stem cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726947

Induced pluripotent stem cells generated from patients with ALS can be differentiated into motor neurons

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726947

Differentiation of human embryonic stem cells to regional specific neural precursors in chemically defined medium conditions

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726947

Directed differentiation of ventral spinal progenitors and motor neurons from human embryonic stem cells by small molecules

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726947

Neural stem cell engineering: directed differentiation of adult and embryonic stem cells into neurons

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726947

Embryonic stem cells and prospects for their use in regenerative medicine approaches to motor neurone disease.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726947

Wnt3a regulates survival, expansion, and maintenance of neural progenitors derived from human embryonic stem cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726947

Markers and methods for cell sorting of human embryonic stem cell-derived neural cell populations

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726947

Astrocytes expressing ALS-linked mutated SOD1 release factors selectively toxic to motor neurons

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726947

Human embryonic stem cells for brain repair?

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726947

Nestin-GFP reporter expression defines the quiescent state of skeletal muscle satellite cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726947

Efficient establishment of human embryonic stem cell lines and long-term maintenance with stable karyotype by enzymatic bulk passage

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726947

Identification of a specific inhibitor of the dishevelled PDZ domain

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726947

Functional properties of motoneurons derived from mouse embryonic stem cells.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726947

Inhibition of Hedgehog signaling by direct binding of cyclopamine to Smoothened

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726947

Small molecule modulation of Smoothened activity

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726947

Directed differentiation of embryonic stem cells into motor neurons

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726947

Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726947

Homeobox gene Nkx2.2 and specification of neuronal identity by graded Sonic hedgehog signalling

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726947

Distinct neural stem cells proliferate in response to EGF and FGF in the developing mouse telencephalon.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726947

A new method for the rapid and long term growth of human neural precursor cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726947

Specification of motor neuron identity by the MNR2 homeodomain protein

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726947

Structures of the tyrosine kinase domain of fibroblast growth factor receptor in complex with inhibitors

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726947

Two critical periods of Sonic Hedgehog signaling required for the specification of motor neuron identity

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726947

Clonal and population analyses demonstrate that an EGF-responsive mammalian embryonic CNS precursor is a stem cell.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726947

Floor plate and motor neuron induction by different concentrations of the amino-terminal cleavage product of sonic hedgehog autoproteolysis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726947

Isolation, characterization, and use of stem cells from the CNS.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726947

Enrichment of spinal cord cell cultures with motoneurons

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726947

Enhancer-specified GFP-based FACS purification of human spinal motor neurons from embryonic stem cells

21 June 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0006722

Easy and rapid differentiation of embryonic stem cells into functional motoneurons using sonic hedgehog-producing cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0006722

Neural subtype specification of fertilization and nuclear transfer embryonic stem cells and application in parkinsonian mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0006722

Directed differentiation and transplantation of human embryonic stem cell-derived motoneurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0006722

In vitro differentiation of transplantable neural precursors from human embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0006722

Growing and working with spinal motor neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0006722

Direct neural fate specification from embryonic stem cells: a primitive mammalian neural stem cell stage acquired through a default mechanism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0006722

Spatiotemporal recapitulation of central nervous system development by murine embryonic stem cell-derived neural stem/progenitor cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0006722

Requirement for COUP-TFI and II in the temporal specification of neural stem cells in CNS development

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0006722

Noggin and basic FGF were implicated in forebrain fate and caudal fate, respectively, of the neural tube-like structures emerging in mouse ES cell culture

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0006722

Transforming growth factor-alpha null and senescent mice show decreased neural progenitor cell proliferation in the forebrain subependyma.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2726947

Separation of cell types from embryonic chicken and rat spinal cord: characterization of motoneuron-enriched fractions

31 October 2018

1 reference

12 December 2020

Isolation of fetal mouse motor neurons on discontinuous Percoll density gradients

1 reference

12 December 2020

Purification of embryonic rat motoneurons by panning on a monoclonal antibody to the low-affinity NGF receptor

1 reference

12 December 2020

Rapid purification of embryonic rat motoneurons: an in vitro model for studying MND/ALS pathogenesis

1 reference

12 December 2020

Distribution of Sonic hedgehog peptides in the developing chick and mouse embryo

1 reference

12 December 2020

Induction of motor neurons by Sonic hedgehog is independent of floor plate differentiation

1 reference

12 December 2020

Cardiotrophin-1 requires LIFRbeta to promote survival of mouse motoneurons purified by a novel technique

1 reference

12 December 2020

Differentiation of human embryonic stem cells to neural lineages in adherent culture by blocking bone morphogenetic protein signaling

1 reference

12 December 2020

Optimized protocols for isolation of primary motor neurons, astrocytes and microglia from embryonic mouse spinal cord.

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0006722

Identifiers

DOI

1 reference

27 July 2017

0 references

1 reference

27 July 2017

1 reference