(Q33518241)

27 July 2017

title

A genome-wide screen in Saccharomyces cerevisiae reveals a critical role for the mitochondria in the toxicity of a trichothecene mycotoxin (English)

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27 July 2017

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Saccharomyces cerevisiae

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John E McLaughlin

1

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27 July 2017

Mohamed Anwar Bin-Umer

2

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27 July 2017

Andrew Tortora

3

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27 July 2017

Natasha Mendez

4

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27 July 2017

Susan McCormick

5

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27 July 2017

Nilgun E Tumer

6

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27 July 2017

language of work or name

English

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publication date

9 December 2009

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Proceedings of the National Academy of Sciences of the United States of America

27 July 2017

published in

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27 July 2017

volume

106

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27 July 2017

issue

51

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27 July 2017

page(s)

21883-21888

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An ER-mitochondria tethering complex revealed by a synthetic biology screen

27 July 2017

cites work

1 reference

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Ups1p and Ups2p antagonistically regulate cardiolipin metabolism in mitochondria

21 June 2018

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Satratoxin G interaction with 40S and 60S ribosomal subunits precedes apoptosis in the macrophage

21 June 2018

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Mechanisms of deoxynivalenol-induced gene expression and apoptosis

21 June 2018

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Comparative induction of 28S ribosomal RNA cleavage by ricin and the trichothecenes deoxynivalenol and T-2 toxin in the macrophage

21 June 2018

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Genome-wide analysis of Rad52 foci reveals diverse mechanisms impacting recombination

21 June 2018

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Regulation of mitochondrial fusion and division

21 June 2018

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Ups1p, a conserved intermembrane space protein, regulates mitochondrial shape and alternative topogenesis of Mgm1p

21 June 2018

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Systematic identification and functional screens of uncharacterized proteins associated with eukaryotic ribosomal complexes

21 June 2018

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Effects of trichothecene mycotoxins on eukaryotic cells: a review.

21 June 2018

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Structures of five antibiotics bound at the peptidyl transferase center of the large ribosomal subunit

21 June 2018

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Mitochondria-mediated nuclear mutator phenotype in Saccharomyces cerevisiae

21 June 2018

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Yeast sphingolipids: metabolism and biology.

21 June 2018

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Structural basis for the interaction of antibiotics with the peptidyl transferase centre in eubacteria

21 June 2018

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Multiple signals from dysfunctional mitochondria activate the pleiotropic drug resistance pathway in Saccharomyces cerevisiae.

21 June 2018

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Ribotoxic stress response: activation of the stress-activated protein kinase JNK1 by inhibitors of the peptidyl transferase reaction and by sequence-specific RNA damage to the alpha-sarcin/ricin loop in the 28S rRNA.

21 June 2018

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Trichothecene biosynthesis in Fusarium species: chemistry, genetics, and significance

21 June 2018

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Cloning of yeast gene for trichodermin resistance and ribosomal protein L3.

21 June 2018

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Ribosomal protein L3 is involved in replication or maintenance of the killer double-stranded RNA genome of Saccharomyces cerevisiae

21 June 2018

1 reference

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Influence of the membrane on T-2 toxin toxicity in Saccharomyces spp

21 June 2018

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Cycloheximide resistance in yeast: a property of the 60s ribosomal subunit.

21 June 2018

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Biological Assays for Two Mycotoxins Produced by Fusarium tricinctum

21 June 2018

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T-2 mycotoxin inhibits mitochondrial protein synthesis

21 June 2018

1 reference

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The toxicology of mycotoxins

21 June 2018

1 reference

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Characterization of Saccharomyces cerevisiae strains displaying high-level or low-level resistance to trichothecene antibiotics

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799815

Competition between trichodermin and several other sesquiterpene antibiotics for binding to their receptor site(s) on eukaryotic ribosomes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799815

Studies on the mode of action of hygromycin B, an inhibitor of translocation in eukaryotes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799815

Deoxynivalenol induces p38 interaction with the ribosome in monocytes and macrophages.

21 June 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0909777106

Fusarial toxin-induced toxicity in cultured cells and in isolated mitochondria involves PTPC-dependent activation of the mitochondrial pathway of apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0909777106

Trichothecenes induce accumulation of glucosylceramide in neural cells by interfering with lactosylceramide synthase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0909777106

Ydc1p ceramidase triggers organelle fragmentation, apoptosis and accelerated ageing in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0909777106

Loss of mitochondrial DNA under genotoxic stress conditions in the absence of the yeast DNA helicase Pif1p occurs independently of the DNA helicase Rrm3p.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0909777106

Pokeweed antiviral protein regulates the stability of its own mRNA by a mechanism that requires depurination but can be separated from depurination of the alpha-sarcin/ricin loop of rRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0909777106

Mitochondria-targeted green fluorescent proteins: convenient tools for the study of organelle biogenesis in Saccharomyces cerevisiae.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799815

The trichodermin group of antibiotics, inhibitors of peptide bond formation by eukaryotic ribosomes

31 October 2018

1 reference

12 December 2020

Comparative toxicology of trichothec mycotoxins: inhibition of protein synthesis in animal cells

1 reference

12 December 2020

Simultaneous ribosomal resistance to trichodermin and anisomycin in Saccharomyces cerevisiae mutants

1 reference

12 December 2020

Analysis and manipulation of yeast mitochondrial genes

1 reference

12 December 2020

Trichothecene mycotoxins trigger a ribotoxic stress response that activates c-Jun N-terminal kinase and p38 mitogen-activated protein kinase and induces apoptosis

1 reference

12 December 2020

An amphibian-derived, cationic, ?-helical antimicrobial peptide kills yeast by caspase-independent but AIF-dependent programmed cell death

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0909777106

1 reference

27 July 2017

0 references

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27 July 2017

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