(Q33519074)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20016840%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

title

Cardiac glycosides induce cell death in human cells by inhibiting general protein synthesis (English)

1 reference

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15 January 2020

1 reference

8

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15 January 2020

Gregor Hoermann

9

1 reference

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15 January 2020

author name string

Andrea Perne

1

1 reference

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15 January 2020

Markus K Muellner

2

1 reference

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15 January 2020

Magdalena Steinrueck

3

1 reference

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15 January 2020

Nils Craig-Mueller

4

1 reference

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15 January 2020

Julia Mayerhofer

5

1 reference

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15 January 2020

Ilse Schwarzinger

6

1 reference

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15 January 2020

Mathew Sloane

7

1 reference

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15 January 2020

Sebastian M B Nijman

10

1 reference

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15 January 2020

Matthias Mayerhofer

11

1 reference

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15 January 2020

language of work or name

English

0 references

publication date

16 December 2009

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15 January 2020

1 reference

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15 January 2020

volume

4

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15 January 2020

issue

12

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15 January 2020

page(s)

e8292

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Creative Commons Attribution 4.0 International

15 January 2020

copyright license

start time

16 December 2009

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Cardiac glycosides inhibit p53 synthesis by a mechanism relieved by Src or MAPK inhibition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788214

Inhibition of the sodium potassium adenosine triphosphatase pump sensitizes cancer cells to anoikis and prevents distant tumor formation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788214

Digoxin treatment is associated with an increased incidence of breast cancer: a population-based case-control study

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788214

Digoxin and other cardiac glycosides inhibit HIF-1alpha synthesis and block tumor growth

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788214

Novel therapeutic applications of cardiac glycosides

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788214

NCCN Task Force Report: mTOR inhibition in solid tumors.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788214

High-throughput screening identifies cardiac glycosides as potent inhibitors of human tissue kallikrein expression: implications for cancer therapies

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788214

Inhibition of the sodium/potassium ATPase impairs N-glycan expression and function

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788214

Efficacy of everolimus in advanced renal cell carcinoma: a double-blind, randomised, placebo-controlled phase III trial

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788214

UNBS5162, a novel naphthalimide that decreases CXCL chemokine expression in experimental prostate cancers

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788214

The sodium pump alpha1 subunit as a potential target to combat apoptosis-resistant glioblastomas

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788214

Cardiotonic steroids on the road to anti-cancer therapy

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788214

Endogenous and exogenous cardiac glycosides: their roles in hypertension, salt metabolism, and cell growth

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788214

Gene expression signature-based chemical genomic prediction identifies a novel class of HSP90 pathway modulators

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788214

Gene expression-based chemical genomics identifies rapamycin as a modulator of MCL1 and glucocorticoid resistance

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788214

The Connectivity Map: using gene-expression signatures to connect small molecules, genes, and disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788214

Ouabain, a steroid hormone that signals with slow calcium oscillations.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788214

Digitoxin medication and cancer; case control and internal dose-response studies

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788214

Mechanisms of sodium pump regulation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788214

Clinical features and management of digitalis poisoning--rationale for immunotherapy

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788214

Comparison of labelling by bromodeoxyuridine, MIB-1, and proliferating cell nuclear antigen in gastric mucosal biopsy specimens

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788214

Isolation of ouabain-resistant human diploid fibroblasts.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788214

Altered biochemical properties of actin in normal skin fibroblasts from individuals predisposed to dominantly inherited cancers.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788214

Expression of an ouabain-resistant Na,K-ATPase in CV-1 cells after transfection with a cDNA encoding the rat Na,K-ATPase alpha 1 subunit.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788214

Phase II evaluation of didemnin B in advanced adenocarcinoma of the kidney. A Southwest Oncology Group study

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788214

Anti-tumor activities and apoptosis-regulated mechanisms of bufalin on the orthotopic transplantation tumor model of human hepatocellular carcinoma in nude mice.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788214

Risk factors for male breast cancer--a case-control study from Scandinavia

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788214

Electrophysiological analysis of the substrate selectivity of a sodium-coupled nucleoside transporter (rCNT1) expressed in Xenopus laevis oocytes.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788214

Anti-tumor promoting activities of natural products. II. Inhibitory effects of digitoxin on two-stage carcinogenesis of mouse skin tumors and mouse pulmonary tumors.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2788214

Is digitalis a therapy for breast carcinoma?

31 October 2018

1 reference

12 December 2020

Different protein turnover of interleukin-6-type cytokine signalling components

1 reference

12 December 2020

Dissociation of ribonucleic acid and protein synthesis in bacteria deprived of potassium

1 reference

12 December 2020

ON THE ROLE OF INTRACELLULAR POTASSIUM IN PROTEIN SYNTHESIS

1 reference

12 December 2020

Clinical Evaluation of Puromycin in Human neoplastic Disease

1 reference

12 December 2020

Digoxin inhibits neuroblastoma tumor growth in mice

1 reference

12 December 2020

Phase II trial of didemnin-B in advanced epithelial ovarian cancer. A Southwest Oncology Group study

1 reference

12 December 2020

Monovalent Cation Requirement for the Aminoacyl Transfer Reaction in Protein Synthesis

1 reference

12 December 2020

Inhibition of elongation steps of protein synthesis at reduced potassium concentrations in reticulocytes and reticulocyte lysate

1 reference

12 December 2020

Cardiac glycosides and breast cancer, revisited

1 reference

12 December 2020

Phase I study of RP 49532A, a new protein-synthesis inhibitor, in patients with advanced refractory solid tumors

1 reference

12 December 2020

Cardiac glycosides and breast cancer

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0008292

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20016840%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20016840%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

1 reference