(Q33521710)

27 July 2017

title

Induction of ovarian leiomyosarcomas in mice by conditional inactivation of Brca1 and p53. (English)

1 reference

27 July 2017

Bridget A Quinn

1

1 reference

27 July 2017

Tiffany Brake

2

1 reference

27 July 2017

Xiang Hua

3

1 reference

27 July 2017

Kimberly Baxter-Jones

4

1 reference

27 July 2017

Samuel Litwin

5

1 reference

27 July 2017

Lora Hedrick Ellenson

6

1 reference

27 July 2017

Denise C Connolly

7

1 reference

27 July 2017

language of work or name

English

0 references

publication date

31 December 2009

1 reference

27 July 2017

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27 July 2017

volume

4

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27 July 2017

issue

12

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27 July 2017

page(s)

e8404

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Creative Commons Attribution 4.0 International

27 July 2017

copyright license

start time

31 December 2009

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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Candidate serous cancer precursors in fallopian tube epithelium of BRCA1/2 mutation carriers.

21 June 2018

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Intercepting early pelvic serous carcinoma by routine pathological examination of the fimbria

21 June 2018

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Hereditary ovarian carcinoma: heterogeneity, molecular genetics, pathology, and management

21 June 2018

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Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor

21 June 2018

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A candidate precursor to pelvic serous cancer (p53 signature) and its prevalence in ovaries and fallopian tubes from women with BRCA mutations

21 June 2018

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Somatic loss of BRCA1 and p53 in mice induces mammary tumors with features of human BRCA1-mutated basal-like breast cancer

21 June 2018

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A candidate precursor to serous carcinoma that originates in the distal fallopian tube.

21 June 2018

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A mouse model for the molecular characterization of brca1-associated ovarian carcinoma

21 June 2018

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Total-genome analysis of BRCA1/2-related invasive carcinomas of the breast identifies tumor stroma as potential landscaper for neoplastic initiation.

21 June 2018

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Modulation of aromatase expression by BRCA1: a possible link to tissue-specific tumor suppression.

21 June 2018

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21 June 2018

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BRCA1 and BRCA2: 1994 and beyond

21 June 2018

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Epigenetic factors controlling the BRCA1 and BRCA2 genes in sporadic ovarian cancer.

21 June 2018

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Induction of ovarian cancer by defined multiple genetic changes in a mouse model system

21 June 2018

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Cancer susceptibility and the functions of BRCA1 and BRCA2

21 June 2018

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Multiple genetic changes are associated with mammary tumorigenesis in Brca1 conditional knockout mice

21 June 2018

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A somatic mutation in the 5'UTR of BRCA1 gene in sporadic breast cancer causes down-modulation of translation efficiency.

21 June 2018

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Prevalence and penetrance of germline BRCA1 and BRCA2 mutations in a population series of 649 women with ovarian cancer

21 June 2018

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Somatic mutations in the STK11/LKB1 gene are uncommon in rare gynecological tumor types associated with Peutz-Jegher's syndrome

21 June 2018

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Conditional mutation of Brca1 in mammary epithelial cells results in blunted ductal morphogenesis and tumour formation.

21 June 2018

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Inducible gene targeting in mice using the Cre/lox system

21 June 2018

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p53 gene mutations are common in uterine serous carcinoma and occur early in their pathogenesis.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2796165

Somatic point mutations in the p53 gene of human tumors and cell lines: updated compilation

21 June 2018

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Spontaneous and carcinogen-induced tumorigenesis in p53-deficient mice.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2796165

Gain of function mutations in p53.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2796165

Tumor spectrum analysis in p53-mutant mice

21 June 2018

1 reference

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Complementary deoxyribonucleic acid cloning and molecular characterization of an estrogen-dependent human oviductal glycoprotein

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2796165

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2796165

Mouse model of human ovarian endometrioid adenocarcinoma based on somatic defects in the Wnt/beta-catenin and PI3K/Pten signaling pathways.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2796165

Conditional inactivation of Brca1 in the mouse ovarian surface epithelium results in an increase in preneoplastic changes.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2796165

The tubal fimbria is a preferred site for early adenocarcinoma in women with familial ovarian cancer syndrome.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2796165

Selective evolution of stromal mesenchyme with p53 loss in response to epithelial tumorigenesis.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2796165

BRCA1 and BRCA2 mutations account for a large proportion of ovarian carcinoma cases

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2796165

Cell-nonautonomous induction of ovarian and uterine serous cystadenomas in mice lacking a functional Brca1 in ovarian granulosa cells

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2796165

Role of K-ras and Pten in the development of mouse models of endometriosis and endometrioid ovarian cancer

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2796165

Gain of function of a p53 hot spot mutation in a mouse model of Li-Fraumeni syndrome.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2796165

Oviductal glycoprotein, a new differentiation-based indicator present in early ovarian epithelial neoplasia and cortical inclusion cysts.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2796165

Induction of carcinogenesis by concurrent inactivation of p53 and Rb1 in the mouse ovarian surface epithelium.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2796165

Female mice chimeric for expression of the simian virus 40 TAg under control of the MISIIR promoter develop epithelial ovarian cancer.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2796165

Methylation profiles of sporadic ovarian tumors and nonmalignant ovaries from high-risk women.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2796165

The IARC TP53 database: new online mutation analysis and recommendations to users

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2796165

Synergistic tumor suppressor activity of BRCA2 and p53 in a conditional mouse model for breast cancer.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2796165

The p53 mutational spectrum associated with BRCA1 mutant ovarian cancer.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2796165

Molecular genetic characterization of BRCA1- and BRCA2-linked hereditary ovarian cancers

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2796165

Breast-Cancer Stromal Cells withTP53Mutations and Nodal Metastases

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2796165

Inactivation of BRCA1 and BRCA2 in ovarian cancer

31 October 2018

1 reference

12 December 2020

Chromosome stability, in the absence of apoptosis, is critical for suppression of tumorigenesis in Trp53 mutant mice

1 reference

12 December 2020

Primary ovarian sarcoma: analysis of prognostic variables and the role of surgical cytoreduction

1 reference

12 December 2020

Increased frequency ofTP53 mutations inBRCA1 andBRCA2 ovarian tumours

1 reference

12 December 2020

Mutant p53 gain of function in two mouse models of Li-Fraumeni syndrome

1 reference

12 December 2020

1 reference

12 December 2020

Frequency of BRCA1 dysfunction in ovarian cancer

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0008404

Identifiers

DOI

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27 July 2017

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27 July 2017

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