(Q33523440)

27 July 2017

title

Human monomeric antibody fragments to TRAIL-R1 and TRAIL-R2 that display potent in vitro agonism (English)

1 reference

27 July 2017

1 reference

Claire L Dobson

1

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27 July 2017

Sarah Main

2

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27 July 2017

Philip Newton

3

1 reference

27 July 2017

Matthieu Chodorge

4

1 reference

27 July 2017

Karen Cadwallader

5

1 reference

27 July 2017

Robin Humphreys

6

1 reference

27 July 2017

Vivian Albert

7

1 reference

27 July 2017

Tristan J Vaughan

8

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27 July 2017

Ralph R Minter

9

1 reference

27 July 2017

Bryan M Edwards

10

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27 July 2017

publication date

11 November 2009

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27 July 2017

published in

Monoclonal Antibodies

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27 July 2017

volume

1

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27 July 2017

issue

6

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27 July 2017

page(s)

552-562

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Modelling the human immune response: performance of a 1011 human antibody repertoire against a broad panel of therapeutically relevant antigens

27 July 2017

cites work

1 reference

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The conformation of the extracellular binding domain of Death Receptor 5 in the presence and absence of the activating ligand TRAIL: a molecular dynamics study

21 June 2018

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Tumor-derived mutations in the TRAIL receptor DR5 inhibit TRAIL signaling through the DR4 receptor by competing for ligand binding

21 June 2018

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Activation of the proapoptotic death receptor DR5 by oligomeric peptide and antibody agonists

21 June 2018

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Combined treatment of colorectal tumours with agonistic TRAIL receptor antibodies HGS-ETR1 and HGS-ETR2 and radiotherapy: enhanced effects in vitro and dose-dependent growth delay in vivo

21 June 2018

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Preligand assembly domain-mediated ligand-independent association between TRAIL receptor 4 (TR4) and TR2 regulates TRAIL-induced apoptosis

21 June 2018

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A novel anti-human DR5 monoclonal antibody with tumoricidal activity induces caspase-dependent and caspase-independent cell death

21 June 2018

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Activity of selective fully human agonistic antibodies to the TRAIL death receptors TRAIL-R1 and TRAIL-R2 in primary and cultured lymphoma cells: induction of apoptosis and enhancement of doxorubicin- and bortezomib-induced cell death

21 June 2018

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Molecular recognition by a binary code

21 June 2018

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HGS-ETR1, a fully human TRAIL-receptor 1 monoclonal antibody, induces cell death in multiple tumour types in vitro and in vivo

21 June 2018

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Enhanced apoptosis and tumor regression induced by a direct agonist antibody to tumor necrosis factor-related apoptosis-inducing ligand receptor 2.

21 June 2018

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TRAIL and its receptors as targets for cancer therapy

21 June 2018

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Targeting death receptors in cancer with Apo2L/TRAIL.

21 June 2018

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NK cell TRAIL eliminates immature dendritic cells in vivo and limits dendritic cell vaccination efficacy

21 June 2018

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The Remarkable Flexibility of the Human Antibody Repertoire; Isolation of Over One Thousand Different Antibodies to a Single Protein, BLyS

21 June 2018

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Human normal hepatocytes are susceptible to apoptosis signal mediated by both TRAIL-R1 and TRAIL-R2

21 June 2018

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TRAIL/Apo-2 ligand induces primary plasma cell apoptosis

21 June 2018

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Death ligand TRAIL induces no apoptosis but inhibits activation of human (auto)antigen-specific T cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791312

Critical role for tumor necrosis factor-related apoptosis-inducing ligand in immune surveillance against tumor development

21 June 2018

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Tumoricidal activity of a novel anti-human DR5 monoclonal antibody without hepatocyte cytotoxicity.

21 June 2018

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Antibodies in haystacks: how selection strategy influences the outcome of selection from molecular diversity libraries

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791312

FADD/MORT1 and caspase-8 are recruited to TRAIL receptors 1 and 2 and are essential for apoptosis mediated by TRAIL receptor 2

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791312

A domain in TNF receptors that mediates ligand-independent receptor assembly and signaling

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791312

Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is an inhibitor of autoimmune inflammation and cell cycle progression

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791312

Triggering cell death: the crystal structure of Apo2L/TRAIL in a complex with death receptor 5

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791312

Safety and antitumor activity of recombinant soluble Apo2 ligand

21 June 2018

1 reference

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To die or not to die--the quest of the TRAIL receptors

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791312

Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791312

Human antibodies with sub-nanomolar affinities isolated from a large non-immunized phage display library

21 June 2018

1 reference

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Osteoprotegerin is a receptor for the cytotoxic ligand TRAIL.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791312

Efficient construction of a large nonimmune phage antibody library: the production of high-affinity human single-chain antibodies to protein antigens

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791312

Death receptor 5, a new member of the TNFR family, and DR4 induce FADD-dependent apoptosis and activate the NF-kappaB pathway

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791312

Agonistic activity of a CD40-specific single-chain Fv constructed from the variable regions of mAb G28-5.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791312

A novel receptor for Apo2L/TRAIL contains a truncated death domain

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791312

Cloning and characterization of TRAIL-R3, a novel member of the emerging TRAIL receptor family

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791312

TRAIL-R2: a novel apoptosis-mediating receptor for TRAIL.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791312

TRICK2, a new alternatively spliced receptor that transduces the cytotoxic signal from TRAIL

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791312

Direct demonstration of MuSK involvement in acetylcholine receptor clustering through identification of agonist ScFv

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791312

Control of TRAIL-induced apoptosis by a family of signaling and decoy receptors

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791312

An antagonist decoy receptor and a death domain-containing receptor for TRAIL

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791312

The receptor for the cytotoxic ligand TRAIL

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791312

Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor cytokine family

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791312

Isolation of high-affinity monomeric human anti-c-erbB-2 single chain Fv using affinity-driven selection

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791312

Recombinant anti-sialidase single-chain variable fragment antibody. Characterization, formation of dimer and higher-molecular-mass multimers and the solution of the crystal structure of the single-chain variable fragment/sialidase complex.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791312

Isolation of high affinity human antibodies directly from large synthetic repertoires.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791312

Selection of phage antibodies by binding affinity. Mimicking affinity maturation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791312

Increased susceptibility to tumor initiation and metastasis in TNF-related apoptosis-inducing ligand-deficient mice

21 June 2018

1 reference

https://api.crossref.org/works/10.4161%2FMABS.1.6.10057

Characterization of the in vivo function of TNF-alpha-related apoptosis-inducing ligand, TRAIL/Apo2L, using TRAIL/Apo2L gene-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FMABS.1.6.10057

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FMABS.1.6.10057

Expression of TRAIL and TRAIL receptors in normal and malignant tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FMABS.1.6.10057

Selection of phage antibodies by binding affinity

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FMABS.1.6.10057

Characterisation of monoclonal antibodies to the TNF and TNF receptor families

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FMABS.1.6.10057

Purification of bacterially expressed single chain Fv antibodies for clinical applications using metal chelate chromatography

21 January 2018

1 reference

12 December 2020

Functional analysis of TRAIL receptors using monoclonal antibodies

1 reference

12 December 2020

Cutting Edge: TRAIL Deficiency Accelerates Hematological Malignancies

1 reference

12 December 2020

Isotype-dependent inhibition of tumor growth in vivo by monoclonal antibodies to death receptor 4

1 reference

12 December 2020

Suppression of antibody production by TNF-related apoptosis-inducing ligand (TRAIL)

1 reference

12 December 2020

Defective thymocyte apoptosis and accelerated autoimmune diseases in TRAIL-/- mice

1 reference

12 December 2020

Identifiers

DOI

10.4161/MABS.1.6.10057

1 reference

27 July 2017

1 reference

27 July 2017

1 reference