(Q33533831)

27 July 2017

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title

Genomics and the discovery of new drug targets (English)

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27 July 2017

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Jones DA

1

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27 July 2017

Fitzpatrick FA

series ordinal

2

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27 July 2017

language of work or name

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1 February 1999

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Current Opinion in Chemical Biology

27 July 2017

published in

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27 July 2017

volume

3

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27 July 2017

issue

1

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27 July 2017

page(s)

71-76

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Genes, disease and medicine

27 July 2017

cites work

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7 January 2021

From expressed sequence tags to 'epigenomics': an understanding of disease processes

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7 January 2021

Identification and characterization of a new member of the TNF family that induces apoptosis

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7 January 2021

APRIL, a new ligand of the tumor necrosis factor family, stimulates tumor cell growth

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7 January 2021

Characterization of a novel TNF-like ligand and recently described TNF ligand and TNF receptor superfamily genes and their constitutive and inducible expression in hematopoietic and non-hematopoietic cells

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7 January 2021

Basic local alignment search tool

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7 January 2021

Signal transduction by DR3, a death domain-containing receptor related to TNFR-1 and CD95

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7 January 2021

The receptor for the cytotoxic ligand TRAIL

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7 January 2021

A newly identified member of the tumor necrosis factor receptor superfamily with a wide tissue distribution and involvement in lymphocyte activation

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7 January 2021

An antagonist decoy receptor and a death domain-containing receptor for TRAIL

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7 January 2021

Control of TRAIL-induced apoptosis by a family of signaling and decoy receptors

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7 January 2021

Cathepsin K, but not cathepsins B, L, or S, is abundantly expressed in human osteoclasts

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7 January 2021

Peptide aldehyde inhibitors of cathepsin K inhibit bone resorption both in vitro and in vivo

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7 January 2021

Crystal structure of human cathepsin K complexed with a potent inhibitor

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7 January 2021

Crystal structure of human osteoclast cathepsin K complex with E-64

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7 January 2021

Pycnodysostosis, a lysosomal disease caused by cathepsin K deficiency

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7 January 2021

An information-intensive approach to the molecular pharmacology of cancer.

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7 January 2021

Proteome and proteomics: new technologies, new concepts, and new words

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7 January 2021

Rapid mass spectrometric identification of proteins from two-dimensional polyacrylamide gels after in gel proteolytic digestion.

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7 January 2021

Peptide mass fingerprint sequence coverage from differently stained proteins on two-dimensional electrophoresis patterns by matrix assisted laser desorption/ionization-mass spectrometry (MALDI-MS).

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7 January 2021

A protein expression database for the molecular pharmacology of cancer.

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7 January 2021

The effects of peroxisome proliferators on protein abundances in mouse liver

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Microarrays: biotechnology's discovery platform for functional genomics.

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Quantitative monitoring of gene expression patterns with a complementary DNA microarray

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7 January 2021

Use of a cDNA microarray to analyse gene expression patterns in human cancer

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7 January 2021

Parallel human genome analysis: microarray-based expression monitoring of 1000 genes

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7 January 2021

Expression monitoring by hybridization to high-density oligonucleotide arrays

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7 January 2021

A DNA microarray system for analyzing complex DNA samples using two-color fluorescent probe hybridization

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7 January 2021

Genome-wide expression monitoring in Saccharomyces cerevisiae

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7 January 2021

Discovery and analysis of inflammatory disease-related genes using cDNA microarrays

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7 January 2021

Exploring the metabolic and genetic control of gene expression on a genomic scale

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7 January 2021

Exploiting chemical libraries, structure, and genomics in the search for kinase inhibitors

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7 January 2021

Ribozymes as human therapeutic agents

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7 January 2021

Genomic strategies for defining and dissecting developmental and physiological pathways.

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7 January 2021

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7 January 2021

Oligonucleotide facilitators enable a hammerhead ribozyme to cleave long RNA substrates with multiple-turnover activity

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7 January 2021

HER-2/neu is rate-limiting for ovarian cancer growth. Conditional depletion of HER-2/neu by ribozyme targeting.

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7 January 2021

Antisense DNA downregulation of the ERBB2 oncogene measured by a flow cytometric assay

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7 January 2021

Therapeutic application of anti-growth factor receptor antibodies

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7 January 2021

Intracellular antibodies (intrabodies) for gene therapy of infectious diseases

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7 January 2021

An intracellular anti-erbB-2 single-chain antibody is specifically cytotoxic to human breast carcinoma cells overexpressing erbB-2.

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7 January 2021

The level of erbB2 expression predicts sensitivity to the cytotoxic effects of an intracellular anti-erbB2 sFv.

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7 January 2021

10.1016/S1367-5931(99)80013-1

Identifiers

DOI

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27 July 2017

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