(Q33538109)

27 July 2017

1 reference

title

DNA adduct formation from tobacco-specific N-nitrosamines (English)

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27 July 2017

Hecht SS

1

1 reference

PubMed ID

10064856

27 July 2017

language of work or name

English

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publication date

1 March 1999

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27 July 2017

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27 July 2017

424

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27 July 2017

127-142

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27 July 2017

1-2

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Tobacco-specific nitrosamines, an important group of carcinogens in tobacco and tobacco smoke.

27 July 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900014-7

Tobacco-specific N-nitrosamines and Areca-derived N-nitrosamines: chemistry, biochemistry, carcinogenicity, and relevance to humans

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900014-7

Biochemistry, biology, and carcinogenicity of tobacco-specific N-nitrosamines.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900014-7

A tobacco-specific lung carcinogen in the urine of men exposed to cigarette smoke

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900014-7

Cigarette smoking and changes in the histopathology of lung cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900014-7

Five leading U.S. commercial brands of moist snuff in 1994: assessment of carcinogenic N-nitrosamines.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900014-7

Unusually high levels of carcinogenic tobacco-specific nitrosamines in Sudan snuff (toombak).

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900014-7

Glucuronidation of 4-((hydroxymethyl)nitrosamino)-1-(3-pyridyl)-1-butanone, a metabolically activated form of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, by phenobarbital-treated rats

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900014-7

In vivo and in vitro persistence of pyridyloxobutyl DNA adducts from 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900014-7

Comparative mutagenicity of 4-(carbethoxynitrosamino)-4-(3-pyridyl)butanal and 4-(carbethoxynitrosamino)-1-(3-pyridyl)-1-butanone, model compounds for alpha-hydroxylation of N'-nitrosonornicotine

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900014-7

Investigations of metabolic precursors to hemoglobin and DNA adducts of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900014-7

Solvolysis of model compounds for alpha-hydroxylation of N'-nitrosonornicotine and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone: evidence for a cyclic oxonium ion intermediate in the alkylation of nucleophiles.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900014-7

Evidence for 4-(3-pyridyl)-4-oxobutylation of DNA in F344 rats treated with the tobacco-specific nitrosamines 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and N'-nitrosonornicotine.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900014-7

Analysis for N2-(pyridyloxobutyl)deoxyguanosine adducts in DNA of tissues exposed to tritium-labeled 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and N'-nitrosonornicotine

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900014-7

Analysis of mutagenic activity and ability to induce replication of polyoma DNA sequences by different model metabolites of the carcinogenic tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900014-7

Pyridyloxobutyl adduct O6-[4-oxo-4-(3-pyridyl)butyl]guanine is present in 4-(acetoxymethylnitrosamino)-1-(3-pyridyl)-1-butanone-treated DNA and is a substrate for O6-alkylguanine-DNA alkyltransferase.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900014-7

DNA and hemoglobin alkylation by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and its major metabolite 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol in F344 rats

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900014-7

Mass spectrometric analysis of tobacco-specific nitrosamine-DNA adducts in smokers and nonsmokers

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900014-7

Reactions of alpha-acetoxy-N-nitrosopyrrolidine and alpha-acetoxy-N-nitrosopiperidine with deoxyguanosine: formation of N2-tetrahydrofuranyl and N2-tetrahydropyranyl adducts.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900014-7

Formation of N2-tetrahydrofuranyl and N2-tetrahydropyranyl adducts in the reactions of alpha-acetoxy-N-nitrosopyrrolidine and alpha-acetoxy-N-nitrosopiperidine with DNA

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900014-7

Pyridyloxobutylation of Guanine Residues by 4-[(Acetoxymethyl)nitrosamino]-1-(3-pyridyl)-1-butanone Generates Substrates ofO6-Alkylguanine−DNA Alkyltransferase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900014-7

Cell specific differences in O6-methylguanine-DNA methyltransferase activity and removal of O6-methylguanine in rat pulmonary cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900014-7

Matabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) by cytochrome P450IIB1 in a reconstituted system

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900014-7

Effects of long term dietary phenethyl isothiocyanate on the microsomal metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol in F344 rats.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900014-7

Dose-response study of the carcinogenicity of tobacco-specific N-nitrosamines in F344 rats

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900014-7

Cell specificity for the pulmonary metabolism of tobacco-specific nitrosamines in the Fischer rat.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900014-7

Kinetics and enzyme involvement in the metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in microsomes of rat lung and nasal mucosa

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900014-7

Rapid single-dose model for lung tumor induction in A/J mice by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and the effect of diet

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900014-7

Comparison of pulmonary O6-methylguanine DNA adduct levels and Ki-ras activation in lung tumors from resistant and susceptible mouse strains.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900014-7

Effects of deuterium substitution on the tumorigenicity of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol in A/J mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900014-7

Lack of correlation between DNA methylation and hepatocarcinogenesis in rats and hamsters treated with 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900014-7

7-Alkyldeoxyguanosine adduct detection by two-step HPLC and the 32P-postlabeling assay.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900014-7

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900014-7

Human lung carcinogen-DNA adduct levels mediated by genetic polymorphisms in vivo

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900014-7

Distribution of 7-alkyl-2'-deoxyguanosine adduct levels in human lung.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900014-7

Detection of N7-methyldeoxyguanosine adducts in human pulmonary alveolar cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900014-7

O(6)-methyldeoxyguanosine in oesophageal DNA among individuals at high risk of oesophageal cancer.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900014-7

Tobacco smoke-associated N7-alkylguanine in DNA of larynx tissue and leucocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900014-7

Detection of O6-methylguanine, O4-methylthymine and O4-ethylthymine in human liver and peripheral blood leukocyte DNA

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900014-7

O6-methylguanine in blood leucocyte DNA: an association with the geographic prevalence of gastric cancer and with low levels of serum pepsinogen A, a marker of severe chronic atrophic gastritis. The EUROGAST Study Group

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900014-7

7-Methylguanine levels in DNA of smokers' and non-smokers' total white blood cells, granulocytes and lymphocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900014-7

Urinary excretion of 3-methyladenine after consumption of fish containing high levels of dimethylamine

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900014-7

Cigarette smoking and urinary 3-alkyladenine excretion in man

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900014-7

Urinary excretion of 3-methyladenine and 3-ethyladenine after controlled exposure to tobacco smoke.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900014-7

Comparison of DNA alkali-labile sites induced by 4-(methylnitrosamino)-1(3-pyridyl)-1-butanone and 4-oxo-4-(3-pyridyl)butanal in rat hepatocytes.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900014-7

DNA single-strand breaks and toxicity induced by 4-(methyl-nitrosamino)-1-(3- pyridyl)-1-butanone or N-nitrosodimethylamine in hamster and rat liver

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900014-7

Increased 8-oxodeoxyguanosine levels in lung DNA of A/J mice and F344 rats treated with the tobacco-specific nitrosamine 4-(methylnitrosamine)-1-(3-pyridyl)-1-butanone.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900014-7

Oxidative DNA damage in tissues of pregnant female mice and fetuses caused by the tobacco-specific nitrosamine, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900014-7

Oxygen radicals potentiate the genetic toxicity of tobacco-specific nitrosamines

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900014-7

Cigarette smoking induces an increase in oxidative DNA damage, 8-hydroxydeoxyguanosine, in a central site of the human lung

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900014-7

Evidence for cytochrome P450 2A6 and 3A4 as major catalysts for N'-nitrosonornicotine alpha-hydroxylation by human liver microsomes.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900014-7

Study of DNA methylation by tobacco-specific N-nitrosamines

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900014-7

Nitrosamines and human cancer: introduction and overview

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900014-7

inferred from DOI database lookup

7 January 2021

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Identifiers

DOI

10.1016/S0027-5107(99)00014-7

1 reference

27 July 2017

1 reference

PubMed ID

10064856