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The oncogenic activation of beta-catenin
scientific article
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instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
10072352
retrieved
27 July 2017
review article
1 reference
stated in
Europe PubMed Central
title
The oncogenic activation of beta-catenin
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
10072352
retrieved
27 July 2017
author name string
Polakis P
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
10072352
retrieved
27 July 2017
publication date
1 February 1999
1 reference
stated in
Europe PubMed Central
PubMed ID
10072352
retrieved
27 July 2017
published in
Current Opinion in Genetics & Development
1 reference
stated in
Europe PubMed Central
PubMed ID
10072352
retrieved
27 July 2017
volume
9
1 reference
stated in
Europe PubMed Central
PubMed ID
10072352
retrieved
27 July 2017
issue
1
1 reference
stated in
Europe PubMed Central
PubMed ID
10072352
retrieved
27 July 2017
page(s)
15-21
1 reference
stated in
Europe PubMed Central
PubMed ID
10072352
retrieved
27 July 2017
cites work
Cell adhesion and signal transduction: the Armadillo connection
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980003-3
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7 January 2021
based on heuristic
inferred from DOI database lookup
Drosophila wingless: a paradigm for the function and mechanism of Wnt signaling
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980003-3
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7 January 2021
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inferred from DOI database lookup
Signal transduction of beta-catenin
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980003-3
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7 January 2021
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Binding to cadherins antagonizes the signaling activity of beta-catenin during axis formation in Xenopus
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980003-3
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7 January 2021
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Uncoupling cadherin-based adhesion from wingless signalling in Drosophila.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980003-3
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7 January 2021
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inferred from DOI database lookup
An in vivo structure-function study of armadillo, the beta-catenin homologue, reveals both separate and overlapping regions of the protein required for cell adhesion and for wingless signaling
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980003-3
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7 January 2021
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inferred from DOI database lookup
Many tumors induced by the mouse mammary tumor virus contain a provirus integrated in the same region of the host genome
1 reference
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https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980003-3
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7 January 2021
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Association of the APC gene product with beta-catenin
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980003-3
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7 January 2021
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Association of the APC tumor suppressor protein with catenins
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980003-3
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7 January 2021
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inferred from DOI database lookup
Regulation of intracellular beta-catenin levels by the adenomatous polyposis coli (APC) tumor-suppressor protein
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980003-3
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7 January 2021
based on heuristic
inferred from DOI database lookup
Wnt-1 modulates cell-cell adhesion in mammalian cells by stabilizing beta-catenin binding to the cell adhesion protein cadherin
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980003-3
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7 January 2021
based on heuristic
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Stabilization of beta-catenin by genetic defects in melanoma cell lines
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980003-3
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7 January 2021
based on heuristic
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Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980003-3
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7 January 2021
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inferred from DOI database lookup
Somatic mutations of the APC gene in colorectal tumors: mutation cluster region in the APC gene
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980003-3
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7 January 2021
based on heuristic
inferred from DOI database lookup
Functional interaction of an axin homolog, conductin, with beta-catenin, APC, and GSK3beta
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980003-3
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7 January 2021
based on heuristic
inferred from DOI database lookup
Attenuated familial adenomatous polyposis due to a mutation in the 3' part of the APC gene. A clue for understanding the function of the APC protein
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980003-3
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7 January 2021
based on heuristic
inferred from DOI database lookup
Familial infiltrative fibromatosis (desmoid tumours) (MIM135290) caused by a recurrent 3' APC gene mutation.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980003-3
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7 January 2021
based on heuristic
inferred from DOI database lookup
A Drosophila homolog of the tumor suppressor gene adenomatous polyposis coli down-regulates beta-catenin but its zygotic expression is not essential for the regulation of Armadillo
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980003-3
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7 January 2021
based on heuristic
inferred from DOI database lookup
Adenomatous polyposis coli tumor suppressor protein has signaling activity in Xenopus laevis embryos resulting in the induction of an ectopic dorsoanterior axis
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980003-3
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7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of armadillo by a Drosophila APC inhibits neuronal apoptosis during retinal development
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980003-3
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7 January 2021
based on heuristic
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NH2-terminal deletion of beta-catenin results in stable colocalization of mutant beta-catenin with adenomatous polyposis coli protein and altered MDCK cell adhesion
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980003-3
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7 January 2021
based on heuristic
inferred from DOI database lookup
Deletion of an amino-terminal sequence beta-catenin in vivo and promotes hyperphosporylation of the adenomatous polyposis coli tumor suppressor protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980003-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A mutated beta-catenin gene encodes a melanoma-specific antigen recognized by tumor infiltrating lymphocytes
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980003-3
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7 January 2021
based on heuristic
inferred from DOI database lookup
Somatic mutations of the beta-catenin gene are frequent in mouse and human hepatocellular carcinomas
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980003-3
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7 January 2021
based on heuristic
inferred from DOI database lookup
Expression and hormone regulation of Wnt2, 3, 4, 5a, 7a, 7b and 10b in normal human endometrium and endometrial carcinoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980003-3
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7 January 2021
based on heuristic
inferred from DOI database lookup
Wnt-10b directs hypermorphic development and transformation in mammary glands of male and female mice.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980003-3
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7 January 2021
based on heuristic
inferred from DOI database lookup
A novel human Wnt gene, WNT10B, maps to 12q13 and is expressed in human breast carcinomas
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980003-3
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7 January 2021
based on heuristic
inferred from DOI database lookup
A novel frizzled gene identified in human esophageal carcinoma mediates APC/beta-catenin signals
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980003-3
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7 January 2021
based on heuristic
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Frzb-1 is a secreted antagonist of Wnt signaling expressed in the Spemann organizer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980003-3
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7 January 2021
based on heuristic
inferred from DOI database lookup
Frzb, a secreted protein expressed in the Spemann organizer, binds and inhibits Wnt-8.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980003-3
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7 January 2021
based on heuristic
inferred from DOI database lookup
The cysteine-rich frizzled domain of Frzb-1 is required and sufficient for modulation of Wnt signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980003-3
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7 January 2021
based on heuristic
inferred from DOI database lookup
SARPs: a family of secreted apoptosis-related proteins
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980003-3
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7 January 2021
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Activating Smoothened mutations in sporadic basal-cell carcinoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980003-3
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7 January 2021
based on heuristic
inferred from DOI database lookup
Hedgehog signaling regulates transcription through Gli/Ci binding sites in the wingless enhancer.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980003-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The axis-inducing activity, stability, and subcellular distribution of beta-catenin is regulated in Xenopus embryos by glycogen synthase kinase 3
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980003-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Binding of GSK3beta to the APC-beta-catenin complex and regulation of complex assembly
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980003-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Axin, a negative regulator of the wnt signaling pathway, directly interacts with adenomatous polyposis coli and regulates the stabilization of beta-catenin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980003-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Downregulation of beta-catenin by human Axin and its association with the APC tumor suppressor, beta-catenin and GSK3 beta
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980003-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Axis determination in Xenopus involves biochemical interactions of axin, glycogen synthase kinase 3 and beta-catenin.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980003-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bridging of beta-catenin and glycogen synthase kinase-3beta by axin and inhibition of beta-catenin-mediated transcription
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980003-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3beta and beta-catenin and promotes GSK-3beta-dependent phosphorylation of beta-catenin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980003-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Combinatorial control in ubiquitin-dependent proteolysis: don't Skp the F-box hypothesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980003-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of the Hedgehog and Wingless signalling pathways by the F-box/WD40-repeat protein Slimb
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980003-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
From cadherins to catenins: cytoplasmic protein interactions and regulation of cell adhesion
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980003-3
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7 January 2021
based on heuristic
inferred from DOI database lookup
Beta-catenin mediates the interaction of the cadherin-catenin complex with epidermal growth factor receptor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980003-3
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7 January 2021
based on heuristic
inferred from DOI database lookup
beta-Catenin associates with the actin-bundling protein fascin in a noncadherin complex
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980003-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
XTcf-3 transcription factor mediates beta-catenin-induced axis formation in Xenopus embryos
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980003-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Functional interaction of beta-catenin with the transcription factor LEF-1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980003-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interaction of the DF3/MUC1 breast carcinoma-associated antigen and beta-catenin in cell adhesion
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980003-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The presenilin 1 protein is a component of a high molecular weight intracellular complex that contains beta-catenin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980003-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cellular redistribution of protein tyrosine phosphatases LAR and PTPsigma by inducible proteolytic processing
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980003-3
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7 January 2021
based on heuristic
inferred from DOI database lookup
Role of IQGAP1, a target of the small GTPases Cdc42 and Rac1, in regulation of E-cadherin- mediated cell-cell adhesion
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980003-3
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7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of c-MYC as a target of the APC pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2899%2980003-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0959-437X(99)80003-3
1 reference
stated in
Europe PubMed Central
PubMed ID
10072352
retrieved
27 July 2017
PubMed ID
10072352
1 reference
stated in
Europe PubMed Central
PubMed ID
10072352
retrieved
27 July 2017
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