(Q33540920)

27 July 2017

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title

Mitochondria in organismal aging and degeneration (English)

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27 July 2017

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G A Cortopassi

1

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27 July 2017

A Wong

series ordinal

2

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27 July 2017

language of work or name

English

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publication date

1 February 1999

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Biochimica et Biophysica Acta

27 July 2017

number of pages

11

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based on heuristic

inferred from page(s)

published in

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27 July 2017

volume

1410

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27 July 2017

issue

2

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27 July 2017

page(s)

183-193

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https://api.crossref.org/works/10.1016%2FS0005-2728%2898%2900166-2

27 July 2017

1 reference

Cytogerontology since 1881: a reappraisal of August Weismann and a review of modern progress

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2898%2900166-2

The Janiform genetics of aging

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2898%2900166-2

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2898%2900166-2

Genotypic selection of mitochondrial and oncogenic mutations in human tissue suggests mechanisms of age-related pathophysiology

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2898%2900166-2

There is substantial agreement among interspecies estimates of DNA repair activity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2898%2900166-2

Mitochondrial DNA and human evolution

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2898%2900166-2

Mitochondrial DNA mutations in diseases of energy metabolism

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2898%2900166-2

Genetic analysis of ageing: role of oxidative damage and environmental stresses.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2898%2900166-2

Genetic modulation of the senescent phenotype of Homo sapiens

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2898%2900166-2

The somatic mutation theory of ageing

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2898%2900166-2

BCL2 translocation frequency rises with age in humans

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2898%2900166-2

UV and skin cancer: specific p53 gene mutation in normal skin as a biologically relevant exposure measurement

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2898%2900166-2

Association between cigarette smoking and mutation of the p53 gene in squamous-cell carcinoma of the head and neck

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2898%2900166-2

The biologic clock: the mitochondria?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2898%2900166-2

Mitochondrial DNA mutations as an important contributor to ageing and degenerative diseases

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2898%2900166-2

Mitochondrial theory of senescence: Respiratory chain protein studies in human skeletal muscle

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2898%2900166-2

Detection of a specific mitochondrial DNA deletion in tissues of older humans

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2898%2900166-2

Mitochondrial DNA deletions in human brain: regional variability and increase with advanced age

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2898%2900166-2

Mitochondrial genetics: a paradigm for aging and degenerative diseases?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2898%2900166-2

Multi-organ characterization of mitochondrial genomic rearrangements in ad libitum and caloric restricted mice show striking somatic mitochondrial DNA rearrangements with age

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2898%2900166-2

Marked increase in the number and variety of mitochondrial DNA rearrangements in aging human skeletal muscle

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2898%2900166-2

A pattern of accumulation of a somatic deletion of mitochondrial DNA in aging human tissues

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2898%2900166-2

Increase of deleted mitochondrial DNA in the striatum in Parkinson's disease and senescence

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2898%2900166-2

Accumulation of deletions in human mitochondrial DNA during normal aging: analysis by quantitative PCR

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2898%2900166-2

Multiple mitochondrial DNA deletions associated with age in skeletal muscle of rhesus monkeys.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2898%2900166-2

Mitochondrial DNA transcription and translation in aged rat. Effect of acetyl-L-carnitine

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2898%2900166-2

Detection and quantitation by competitive PCR of an age-associated increase in a 4.8-kb deletion in rat mitochondrial DNA

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2898%2900166-2

Multiple deletions in mitochondrial DNA are present in senescent mouse brain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2898%2900166-2

Multiple deletions are detectable in mitochondrial DNA of aging mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2898%2900166-2

Detection of deletions in the mitochondrial genome of Caenorhabditis elegans

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2898%2900166-2

Mosaicism for a specific somatic mitochondrial DNA mutation in adult human brain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2898%2900166-2

Mitochondrial DNA deletions in progressive external ophthalmoplegia and Kearns-Sayre syndrome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2898%2900166-2

Deletions of muscle mitochondrial DNA in patients with mitochondrial myopathies

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2898%2900166-2

Detection of "deleted" mitochondrial genomes in cytochrome-c oxidase-deficient muscle fibers of a patient with Kearns-Sayre syndrome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2898%2900166-2

Spontaneous Kearns-Sayre/chronic external ophthalmoplegia plus syndrome associated with a mitochondrial DNA deletion: a slip-replication model and metabolic therapy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2898%2900166-2

Age-dependent increase in deleted mitochondrial DNA in the human heart: possible contributory factor to presbycardia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2898%2900166-2

Simultaneous increase of mitochondrial DNA deletions and lipid peroxidation in human aging

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2898%2900166-2

Human aging is associated with stochastic somatic mutations of mitochondrial DNA.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2898%2900166-2

Mitochondrial function in muscle from elderly athletes.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2898%2900166-2

Gross mosaic pattern of mitochondrial DNA deletions in skeletal muscle tissues of an individual adult human subject

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2898%2900166-2

The rate of mitochondrial mutagenesis is faster in mice than humans

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2898%2900166-2

Age-associated alterations of the mitochondrial genome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2898%2900166-2

Quantitative allele-specific PCR: demonstration of age-associated accumulation in human tissues of the A-->G mutation at nucleotide 3243 in mitochondrial DNA

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2898%2900166-2

Occurrence of a particular base substitution (3243 A to G) in mitochondrial DNA of tissues of ageing humans

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2898%2900166-2

Human aging is associated with various point mutations in tRNA genes of mitochondrial DNA.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2898%2900166-2

The point mutation of mitochondrial DNA characteristic for MERRF disease is found also in healthy people of different ages

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2898%2900166-2

Respiratory chain failure in adult muscle fibres: relationship with ageing and possible implications for the neuronal pool

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2898%2900166-2

Different in situ hybridization patterns of mitochondrial DNA in cytochrome c oxidase-deficient extraocular muscle fibres in the elderly

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2898%2900166-2

Effects of physical activity and age on mitochondrial function

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2898%2900166-2

Age and oxidative phosphorylation in rat liver and brain.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2898%2900166-2

Modification of mitochondrial respiration by aging and dietary restriction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2898%2900166-2

DECLINE IN SKELETAL MUSCLE MITOCHONDRIAL RESPIRATORY CHAIN FUNCTION: POSSIBLE FACTOR IN AGEING

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2898%2900166-2

Mitochondrial diseases and aging.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2898%2900166-2

Mitochondrial oxidative phosphorylation changes in the life span. Molecular aspects and physiopathological implications

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2898%2900166-2

Ageing is associated in females with a decline in the content and activity on the b-c1 complex in skeletal muscle mitochondria.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2898%2900166-2

Correlation between mitochondrial DNA 4977-bp deletion and respiratory chain enzyme activities in aging human skeletal muscles

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2898%2900166-2

Mitochondrial electron transport chain activities and DNA deletions in regions of the rat brain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2898%2900166-2

Effect of age on oxidative phosphorylation in the rat.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2898%2900166-2

Absence of Relationship between the Level of Electron Transport Chain Activities and Aging in Human Skeletal Muscle

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2898%2900166-2

The universality of bioenergetic disease and amelioration with redox therapy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2898%2900166-2

Mitochondrial decay in hepatocytes from old rats: membrane potential declines, heterogeneity and oxidants increase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2898%2900166-2

Age-dependent modifications of mitochondrial trans-membrane potential and mass in rat splenic lymphocytes during proliferation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2898%2900166-2

Aging, cytochrome oxidase activity, and hydrogen peroxide release by mitochondria.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2898%2900166-2

dATP causes specific release of cytochrome C from mitochondria

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2898%2900166-2

Analysis of oxygen consumption and mitochondrial permeability with age in mice.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2898%2900166-2

Dilated cardiomyopathy and neonatal lethality in mutant mice lacking manganese superoxide dismutase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2898%2900166-2

Neurodegeneration, myocardial injury, and perinatal death in mitochondrial superoxide dismutase-deficient mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2898%2900166-2

Familial mitochondrial encephalomyopathy (MERRF): genetic, pathophysiological, and biochemical characterization of a mitochondrial DNA disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2898%2900166-2

Abnormal calcium homeostasis and mitochondrial polarization in a human encephalomyopathy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2898%2900166-2

mtDNA mutations confer cellular sensitivity to oxidant stress that is partially rescued by calcium depletion and cyclosporin A.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2898%2900166-2

Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2898%2900166-2

Cell-free apoptosis in Xenopus egg extracts: inhibition by Bcl-2 and requirement for an organelle fraction enriched in mitochondria.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2898%2900166-2

Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2898%2900166-2

Sequential reduction of mitochondrial transmembrane potential and generation of reactive oxygen species in early programmed cell death

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2898%2900166-2

Mitochondrial permeability transition is a central coordinating event of apoptosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2898%2900166-2

Bcl-2 potentiates the maximal calcium uptake capacity of neural cell mitochondria

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2898%2900166-2

The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2898%2900166-2

Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2898%2900166-2

The Ca2+-induced membrane transition in mitochondria. I. The protective mechanisms

7 January 2021

2 references

https://api.crossref.org/works/10.1016%2FS0005-2728%2898%2900166-2

7 January 2021

https://api.crossref.org/works/10.1016%2FS0005-2728%2898%2900166-2

inferred from DOI database lookup

7 January 2021

based on heuristic

Mechanisms by which mitochondria transport calcium

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2898%2900166-2

Further evidence that cyclosporin A protects mitochondria from calcium overload by inhibiting a matrix peptidyl-prolyl cis-trans isomerase. Implications for the immunosuppressive and toxic effects of cyclosporin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2898%2900166-2

Induction of the mitochondrial permeability transition causes release of the apoptogenic factor cytochrome c

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2898%2900166-2

Release of cytochrome c from liver mitochondria during permeability transition.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2728%2898%2900166-2

10.1016/S0005-2728(98)00166-2

7 January 2021

Identifiers

DOI

1 reference

27 July 2017

1 reference