(Q33542293)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10081086%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

review article

1 reference

title

Recent advances in identifying and validating drug targets in trypanosomes and leishmanias (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10081086%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

1

1 reference

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12 November 2019

Jeremy C. Mottram

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10081086%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

author name string

G H Coombs

series ordinal

3

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10081086%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

publication date

1 February 1999

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10081086%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

published in

Trends in Microbiology

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10081086%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

volume

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10081086%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

page(s)

82-88

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12 November 2019

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10081086%20AND%20SRC:MED&resulttype=core&format=json

The biogenesis and properties of the parasitophorous vacuoles that harbour Leishmania in murine macrophages

12 November 2019

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0966-842X%2898%2901433-4

7 January 2021

Metabolism and functions of trypanothione in the Kinetoplastida

1 reference

https://api.crossref.org/works/10.1016%2FS0966-842X%2898%2901433-4

7 January 2021

Functional and molecular characterization of a glycosomal PPi-dependent enzyme in trypanosomatids: pyruvate, phosphate dikinase

1 reference

https://api.crossref.org/works/10.1016%2FS0966-842X%2898%2901433-4

7 January 2021

A mitogen-activated protein (MAP) kinase homologue of Leishmania mexicana is essential for parasite survival in the infected host.

1 reference

https://api.crossref.org/works/10.1016%2FS0966-842X%2898%2901433-4

7 January 2021

Gene disruptions indicate an essential function for the LmmCRK1 cdc2-related kinase of Leishmania mexicana.

1 reference

https://api.crossref.org/works/10.1016%2FS0966-842X%2898%2901433-4

7 January 2021

Procyclic Trypanosoma brucei cell lines deficient in ornithine decarboxylase activity

1 reference

https://api.crossref.org/works/10.1016%2FS0966-842X%2898%2901433-4

7 January 2021

Trypanosoma brucei brucei: characterization of an ODC null bloodstream form mutant and the action of alpha-difluoromethylornithine.

1 reference

https://api.crossref.org/works/10.1016%2FS0966-842X%2898%2901433-4

7 January 2021

Gene replacement in parasitic protozoa

1 reference

https://api.crossref.org/works/10.1016%2FS0966-842X%2898%2901433-4

7 January 2021

Double targeted gene replacement for creating null mutants

1 reference

https://api.crossref.org/works/10.1016%2FS0966-842X%2898%2901433-4

7 January 2021

Development of a safe live Leishmania vaccine line by gene replacement.

1 reference

https://api.crossref.org/works/10.1016%2FS0966-842X%2898%2901433-4

7 January 2021

Selection against the dihydrofolate reductase-thymidylate synthase (DHFR-TS) locus as a probe of genetic alterations in Leishmania major.

1 reference

https://api.crossref.org/works/10.1016%2FS0966-842X%2898%2901433-4

7 January 2021

The roles of pteridine reductase 1 and dihydrofolate reductase-thymidylate synthase in pteridine metabolism in the protozoan parasite Leishmania major

1 reference

https://api.crossref.org/works/10.1016%2FS0966-842X%2898%2901433-4

7 January 2021

Biochemical and genetic tests for inhibitors of Leishmania pteridine pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0966-842X%2898%2901433-4

7 January 2021

Prospects for antiparasitic drugs. The case of Trypanosoma brucei, the causative agent of African sleeping sickness

1 reference

https://api.crossref.org/works/10.1016%2FS0966-842X%2898%2901433-4

7 January 2021

Inhibition of the glycolytic enzymes in the trypanosome: an approach in the development of new leads in the therapy of parasitic diseases

1 reference

https://api.crossref.org/works/10.1016%2FS0966-842X%2898%2901433-4

7 January 2021

Disruption of the trypanothione reductase gene of Leishmania decreases its ability to survive oxidative stress in macrophages.

1 reference

https://api.crossref.org/works/10.1016%2FS0966-842X%2898%2901433-4

7 January 2021

Evidence that trypanothione reductase is an essential enzyme in Leishmania by targeted replacement of the tryA gene locus

1 reference

https://api.crossref.org/works/10.1016%2FS0966-842X%2898%2901433-4

7 January 2021

Down-regulation of Leishmania donovani trypanothione reductase by heterologous expression of a trans-dominant mutant homologue: effect on parasite intracellular survival

1 reference

https://api.crossref.org/works/10.1016%2FS0966-842X%2898%2901433-4

7 January 2021

Inducible gene expression in trypanosomes mediated by a prokaryotic repressor.

1 reference

https://api.crossref.org/works/10.1016%2FS0966-842X%2898%2901433-4

7 January 2021

The proteases and pathogenicity of parasitic protozoa

1 reference

https://api.crossref.org/works/10.1016%2FS0966-842X%2898%2901433-4

7 January 2021

Null mutants for the lmcpa cysteine proteinase gene in Leishmania mexicana

1 reference

https://api.crossref.org/works/10.1016%2FS0966-842X%2898%2901433-4

7 January 2021

Cathepsin B-like cysteine proteinase-deficient mutants of Leishmania mexicana.

1 reference

https://api.crossref.org/works/10.1016%2FS0966-842X%2898%2901433-4

7 January 2021

Evidence from disruption of the lmcpb gene array of Leishmania mexicana that cysteine proteinases are virulence factors.

1 reference

https://api.crossref.org/works/10.1016%2FS0966-842X%2898%2901433-4

7 January 2021

Leishmania major: molecular modeling of cysteine proteases and prediction of new nonpeptide inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS0966-842X%2898%2901433-4

7 January 2021

Peptide-fluoromethyl ketones arrest intracellular replication and intercellular transmission of Trypanosoma cruzi

1 reference

https://api.crossref.org/works/10.1016%2FS0966-842X%2898%2901433-4

7 January 2021

Genetic analysis of purine metabolism in Leishmania donovani

1 reference

https://api.crossref.org/works/10.1016%2FS0966-842X%2898%2901433-4

7 January 2021

Creation of homozygous mutants of Leishmania donovani with single targeting constructs

1 reference

https://api.crossref.org/works/10.1016%2FS0966-842X%2898%2901433-4

7 January 2021

Cloning of an avermectin-sensitive glutamate-gated chloride channel from Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1016%2FS0966-842X%2898%2901433-4

7 January 2021

Roles of cysteine proteinases of trypanosomes and Leishmania in host-parasite interactions.

1 reference

https://api.crossref.org/works/10.1016%2FS0966-842X%2898%2901433-4

7 January 2021

Cysteine protease inhibitors cure an experimental Trypanosoma cruzi infection

1 reference

https://api.crossref.org/works/10.1016%2FS0966-842X%2898%2901433-4

7 January 2021

Characterisation of a cysteine protease from bloodstream forms of Trypanosoma congolense.

1 reference

https://api.crossref.org/works/10.1016%2FS0966-842X%2898%2901433-4

7 January 2021

Targeted gene deletion of Leishmania major genes encoding developmental stage-specific leishmanolysin (GP63).

1 reference

https://api.crossref.org/works/10.1016%2FS0966-842X%2898%2901433-4

7 January 2021

The GPI-phospholipase C of Trypanosoma brucei is nonessential but influences parasitemia in mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0966-842X%2898%2901433-4

7 January 2021

10.1016/S0966-842X(98)01433-4

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10081086%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

1 reference