(Q33552783)

28 July 2017

title

Novel 16-substituted bifunctional derivatives of huperzine B: multifunctional cholinesterase inhibitors (English)

1 reference

28 July 2017

Yu-fang Shi

1

1 reference

28 July 2017

Hai-yan Zhang

2

1 reference

28 July 2017

Wei Wang

3

1 reference

28 July 2017

Yan Fu

4

1 reference

28 July 2017

Yu Xia

5

1 reference

28 July 2017

Xi-can Tang

6

1 reference

28 July 2017

Dong-lu Bai

7

1 reference

28 July 2017

Xu-chang He

8

1 reference

28 July 2017

publication date

6 July 2009

1 reference

Acta Pharmacologica Sinica

28 July 2017

published in

1 reference

28 July 2017

volume

30

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28 July 2017

issue

8

1 reference

28 July 2017

page(s)

1195-1203

1 reference

https://scigraph.springernature.com/pub.10.1038/aps.2009.91

28 July 2017

exact match

0 references

cites work

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Targeting beta-amyloid pathogenesis through acetylcholinesterase inhibitors

14 July 2018

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A century of Alzheimer's disease

14 July 2018

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Dimeric and hybrid anti-Alzheimer drug candidates

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006674

Progress in studies of huperzine A, a natural cholinesterase inhibitor from Chinese herbal medicine

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006674

A preclinical view of cholinesterase inhibitors in neuroprotection: do they provide more than symptomatic benefits in Alzheimer's disease?

14 July 2018

1 reference

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Rational approach to discover multipotent anti-Alzheimer drugs.

14 July 2018

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Multi-functional drugs for various CNS targets in the treatment of neurodegenerative disorders

14 July 2018

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Development of bivalent acetylcholinesterase inhibitors as potential therapeutic drugs for Alzheimer's disease.

14 July 2018

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Cholinesterase inhibitors: new roles and therapeutic alternatives

14 July 2018

1 reference

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New trends in the design of drugs against Alzheimer's disease

14 July 2018

1 reference

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Progress in Clinical, Pharmacological, Chemical and Structural Biological Studies of Huperzine A: A Drug of Traditional Chinese Medicine Origin for the Treatment of Alzheimers Disease

14 July 2018

1 reference

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Antioxidant Treatment in Alzheimer's Disease: Current State

14 July 2018

1 reference

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A new and rapid colorimetric determination of acetylcholinesterase activity

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006674

X-ray structures of Torpedo californica acetylcholinesterase complexed with (+)-huperzine A and (-)-huperzine B: structural evidence for an active site rearrangement

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006674

Huperzine B, a novel acetylcholinesterase inhibitor, attenuates hydrogen peroxide induced injury in PC12 cells

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006674

Huperzine A, a potential therapeutic agent for treatment of Alzheimer's disease

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006674

Oxidative stress hypothesis in Alzheimer's disease

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006674

[Improvement of impaired memory in mice by huperzine A and huperzine B]

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006674

Multipotent natural agents to combat Alzheimer's disease. Functional spectrum and structural features

14 July 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2009.91

Acetylcholinesterase accelerates assembly of amyloid-beta-peptides into Alzheimer's fibrils: possible role of the peripheral site of the enzyme.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2009.91

beta-Amyloid aggregation induced by human acetylcholinesterase: inhibition studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2009.91

Synthesis and acetylcholinesterase inhibition of derivatives of huperzine B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2009.91

Study on dual-site inhibitors of acetylcholinesterase: Highly potent derivatives of bis- and bifunctional huperzine B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2009.91

Multi-target-directed drug design strategy: from a dual binding site acetylcholinesterase inhibitor to a trifunctional compound against Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2009.91

Design and synthesis of N-benzylpiperidine-purine derivatives as new dual inhibitors of acetyl- and butyrylcholinesterase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2009.91

Cholinesterase inhibitors: SAR and enzyme inhibitory activity of 3-[omega-(benzylmethylamino)alkoxy]xanthen-9-ones

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006674

Huperzine B protects rat pheochromocytoma cells against oxygen-glucose deprivation-induced injury.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006674

Inhibitory effects of huperzine B on cholinesterase activity in mice.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4006674

Specific Targeting of Acetylcholinesterase and Butyrylcholinesterase Recognition Sites. Rational Design of Novel, Selective, and Highly Potent Cholinesterase Inhibitors

31 October 2018

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2009.91

[Cholinesterase inhibition by huperzine B]

21 January 2018

1 reference

12 December 2020

[Effects of huperzine A and B on skeletal muscle and the electroencephalogram]

1 reference

12 December 2020

Bis-huperzine B: highly potent and selective acetylcholinesterase inhibitors

1 reference

12 December 2020

Homobivalent quinazolinimines as novel nanomolar inhibitors of cholinesterases with dirigible selectivity toward butyrylcholinesterase

1 reference

12 December 2020

The structures of huperzine A and B, two new alkaloids exhibiting marked anticholinesterase activity

1 reference

https://api.crossref.org/works/10.1038%2FAPS.2009.91

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1038/APS.2009.91

1 reference

Dimensions Publication ID

28 July 2017

0 references

1 reference

28 July 2017

1 reference