(Q33564416)

28 July 2017

title

Chemical modifier screen identifies HDAC inhibitors as suppressors of PKD models (English)

1 reference

28 July 2017

Ying Cao

1

1 reference

28 July 2017

Nicole Semanchik

2

1 reference

28 July 2017

Seung Hun Lee

3

1 reference

28 July 2017

Stefan Somlo

4

1 reference

28 July 2017

Paolo Emilio Barbano

5

1 reference

28 July 2017

Ronald Coifman

6

1 reference

28 July 2017

Zhaoxia Sun

7

1 reference

28 July 2017

language of work or name

English

0 references

publication date

4 December 2009

1 reference

Proceedings of the National Academy of Sciences of the United States of America

28 July 2017

published in

1 reference

28 July 2017

volume

106

1 reference

28 July 2017

issue

51

1 reference

28 July 2017

page(s)

21819-21824

1 reference

Small molecule screen for compounds that affect vascular development in the zebrafish retina

28 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799791

Isoform-selective histone deacetylase inhibitors

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799791

Acute kidney injury and aberrant planar cell polarity induce cyst formation in mice lacking renal cilia.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799791

Cyst formation and activation of the extracellular regulated kinase pathway after kidney specific inactivation of Pkd1.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799791

Valproic acid as epigenetic cancer drug: preclinical, clinical and transcriptional effects on solid tumors

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799791

colgate/hdac1 Repression of foxd3 expression is required to permit mitfa-dependent melanogenesis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799791

Histone deacetylase inhibitors: biology and mechanism of action

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799791

HDACs, histone deacetylation and gene transcription: from molecular biology to cancer therapeutics

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799791

Cilia-driven fluid flow in the zebrafish pronephros, brain and Kupffer's vesicle is required for normal organogenesis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799791

Kupffer's vesicle is a ciliated organ of asymmetry in the zebrafish embryo that initiates left-right development of the brain, heart and gut.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799791

Two populations of node monocilia initiate left-right asymmetry in the mouse

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799791

HDAC-6 interacts with and deacetylates tubulin and microtubules in vivo

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799791

The vertebrate primary cilium is a sensory organelle

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799791

Intraflagellar transport and cilia-dependent diseases.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799791

In vivo destabilization of dynamic microtubules by HDAC6-mediated deacetylation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799791

21 June 2018

Intraflagellar transport

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799791

The ion channel polycystin-2 is required for left-right axis determination in mice

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799791

HDAC6 is a microtubule-associated deacetylase

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799791

Deacetylase enzymes: biological functions and the use of small-molecule inhibitors

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799791

TGF-beta superfamily signaling and left-right asymmetry

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799791

vhnf1, the MODY5 and familial GCKD-associated gene, regulates regional specification of the zebrafish gut, pronephros, and hindbrain

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799791

Histone deacetylase is a direct target of valproic acid, a potent anticonvulsant, mood stabilizer, and teratogen

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799791

Randomization of left-right asymmetry due to loss of nodal cilia generating leftward flow of extraembryonic fluid in mice lacking KIF3B motor protein

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799791

Early development of the zebrafish pronephros and analysis of mutations affecting pronephric function.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799791

PKD2, a gene for polycystic kidney disease that encodes an integral membrane protein

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799791

Potent and specific inhibition of mammalian histone deacetylase both in vivo and in vitro by trichostatin A

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799791

A genetic screen in zebrafish identifies cilia genes as a principal cause of cystic kidney

21 June 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0911987106

Histone deacetylase 3 (hdac3) is specifically required for liver development in zebrafish

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0911987106

Histone deacetylase 1 (HDAC-1) required for the normal formation of craniofacial cartilage and pectoral fins of the zebrafish

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0911987106

Histone deacetylase 1 is required to repress Notch target gene expression during zebrafish neurogenesis and to maintain the production of motoneurones in response to hedgehog signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0911987106

Histone deacetylase 1 regulates retinal neurogenesis in zebrafish by suppressing Wnt and Notch signaling pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0911987106

Chemical suppression of a genetic mutation in a zebrafish model of aortic coarctation

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0911987106

The molecular basis of focal cyst formation in human autosomal dominant polycystic kidney disease type I.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0911987106

The role of an endogenous PKA inhibitor, PKIalpha, in organizing left-right axis formation

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799791

Dysregulation of cellular proliferation and apoptosis mediates human autosomal dominant polycystic kidney disease (ADPKD).

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799791

The polycystic kidney disease 1 gene encodes a 14 kb transcript and lies within a duplicated region on chromosome 16. The European Polycystic Kidney Disease Consortium

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799791

Determination of left–right patterning of the mouse embryo by artificial nodal flow

31 October 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0911987106

Taxol inhibits progression of congenital polycystic kidney disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0911987106

Proliferative activity of cyst epithelium in human renal cystic diseases

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19966229

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0911987106

1 reference

28 July 2017

0 references

1 reference

28 July 2017

1 reference