(Q33577361)

28 July 2017

title

Current advances in humanized mouse models (English)

1 reference

28 July 2017

Ryoji Ito

1

1 reference

28 July 2017

Takeshi Takahashi

series ordinal

2

1 reference

28 July 2017

Ikumi Katano

series ordinal

3

1 reference

28 July 2017

Mamoru Ito

series ordinal

4

1 reference

28 July 2017

publication date

13 February 2012

1 reference

Cellular and Molecular Immunology

28 July 2017

published in

1 reference

28 July 2017

volume

9

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28 July 2017

issue

3

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28 July 2017

page(s)

208-214

1 reference

Novel mouse xenograft models reveal a critical role of CD4+ T cells in the proliferation of EBV-infected T and NK cells

28 July 2017

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21 June 2018

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21 June 2018

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Expression of HLA class II molecules in humanized NOD.Rag1KO.IL2RgcKO mice is critical for development and function of human T and B cells

21 June 2018

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Disruption of the Plasmodium falciparum liver-stage antigen-1 locus causes a differentiation defect in late liver-stage parasites

21 June 2018

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A novel animal model of Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis in humanized mice

21 June 2018

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Human thrombopoietin knockin mice efficiently support human hematopoiesis in vivo

21 June 2018

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Human IL-3/GM-CSF knock-in mice support human alveolar macrophage development and human immune responses in the lung

21 June 2018

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Immune reconstitution of the female reproductive tract of humanized BLT mice and their susceptibility to human immunodeficiency virus infection

21 June 2018

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Development of human CD4+FoxP3+ regulatory T cells in human stem cell factor-, granulocyte-macrophage colony-stimulating factor-, and interleukin-3-expressing NOD-SCID IL2Rγ(null) humanized mice

21 June 2018

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The reconstituted 'humanized liver' in TK-NOG mice is mature and functional.

21 June 2018

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A humanized mouse model to study hepatitis C virus infection, immune response, and liver disease.

21 June 2018

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Humanized mice are susceptible to Salmonella typhi infection

21 June 2018

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Failure of effector function of human CD8+ T Cells in NOD/SCID/JAK3⁻/⁻ immunodeficient mice transplanted with human CD34+ hematopoietic stem cells

21 June 2018

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A mouse model for the human pathogen Salmonella typhi

21 June 2018

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Humanized nonobese diabetic-scid IL2rgammanull mice are susceptible to lethal Salmonella Typhi infection.

21 June 2018

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In vivo assay of human NK-dependent ADCC using NOD/SCID/gammac(null) (NOG) mice

21 June 2018

1 reference

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Generation of functional human T-cell subsets with HLA-restricted immune responses in HLA class I expressing NOD/SCID/IL2r gamma(null) humanized mice.

21 June 2018

1 reference

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Current humanized mouse models for studying human immunology and HIV-1 immuno-pathogenesis

21 June 2018

1 reference

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Dynamics of memory and naïve CD8+ T lymphocytes in humanized NOD/SCID/IL-2Rgammanull mice infected with CCR5-tropic HIV-1.

21 June 2018

1 reference

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A defective Il15 allele underlies the deficiency in natural killer cell activity in nonobese diabetic mice

21 June 2018

1 reference

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Human liver chimeric mice provide a model for hepatitis B and C virus infection and treatment

21 June 2018

1 reference

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Parameters for establishing humanized mouse models to study human immunity: analysis of human hematopoietic stem cell engraftment in three immunodeficient strains of mice bearing the IL2rgamma(null) mutation.

21 June 2018

1 reference

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Expression of human cytokines dramatically improves reconstitution of specific human-blood lineage cells in humanized mice

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012844

Repopulation efficiencies of adult hepatocytes, fetal liver progenitor cells, and embryonic stem cell-derived hepatic cells in albumin-promoter-enhancer urokinase-type plasminogen activator mice

21 June 2018

1 reference

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Improved murine model of malaria using Plasmodium falciparum competent strains and non-myelodepleted NOD-scid IL2Rgammanull mice engrafted with human erythrocytes

21 June 2018

1 reference

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Comparison of human fetal liver, umbilical cord blood, and adult blood hematopoietic stem cell engraftment in NOD-scid/gammac-/-, Balb/c-Rag1-/-gammac-/-, and C.B-17-scid/bg immunodeficient mice

21 June 2018

1 reference

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Priming of protective T cell responses against virus-induced tumors in mice with human immune system components

21 June 2018

1 reference

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IL-15 trans-presentation promotes human NK cell development and differentiation in vivo

21 June 2018

1 reference

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Busulfan produces efficient human cell engraftment in NOD/LtSz-Scid IL2Rgamma(null) mice

21 June 2018

1 reference

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Humanized mice for human retrovirus infection.

21 June 2018

1 reference

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NOD/Shi-scid IL2rgamma(null) (NOG) mice more appropriate for humanized mouse models.

21 June 2018

1 reference

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Mouse models with human immunity and their application in biomedical research

21 June 2018

1 reference

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Antiretroviral pre-exposure prophylaxis prevents vaginal transmission of HIV-1 in humanized BLT mice

21 June 2018

1 reference

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Polymorphism in Sirpa modulates engraftment of human hematopoietic stem cells.

21 June 2018

1 reference

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Humanized NOD/SCID/IL2Rgamma(null) mice transplanted with hematopoietic stem cells under nonmyeloablative conditions show prolonged life spans and allow detailed analysis of human immunodeficiency virus type 1 pathogenesis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012844

Identification of a key molecular regulator of liver metastasis in human pancreatic carcinoma using a novel quantitative model of metastasis in NOD/SCID/gammacnull (NOG) mice

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012844

Robust expansion of human hepatocytes in Fah-/-/Rag2-/-/Il2rg-/- mice

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012844

Humanized mice in translational biomedical research

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012844

Hematopoietic stem cell-engrafted NOD/SCID/IL2Rgamma null mice develop human lymphoid systems and induce long-lasting HIV-1 infection with specific humoral immune responses

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012844

Experimental models to study development and function of the human immune system in vivo

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012844

Development of functional human blood and immune systems in NOD/SCID/IL2 receptor {gamma} chain(null) mice

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012844

Human lymphoid and myeloid cell development in NOD/LtSz-scid IL2R gamma null mice engrafted with mobilized human hemopoietic stem cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012844

Retinoic acid syndrome in NOD/scid mice induced by injecting an acute promyelocytic leukemia cell line

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012844

Establishment of a new model of human multiple myeloma using NOD/SCID/gammac(null) (NOG) mice

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012844

Complete reconstitution of human lymphocytes from cord blood CD34+ cells using the NOD/SCID/γcnull mice model

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012844

NOD/SCID/gamma(c)(null) mouse: an excellent recipient mouse model for engraftment of human cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012844

Hepatitis C virus replication in mice with chimeric human livers

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012844

The diverse potential effector and immunoregulatory roles of mast cells in allergic disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012844

Cytokine dependent growth of human TF-1 leukemic cell line in human GM-CSF and IL-3 producing transgenic SCID mice

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012844

Peripheral T cell survival requires continual ligation of the T cell receptor to major histocompatibility complex-encoded molecules

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012844

Establishment of human granulocyte-macrophage colony stimulating factor producing transgenic SCID mice.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012844

The interleukin-2 receptor gamma chain: its role in the multiple cytokine receptor complexes and T cell development in XSCID

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012844

Multiple defects in innate and adaptive immunologic function in NOD/LtSz-scid mice

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012844

A severe combined immunodeficiency mutation in the mouse

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012844

The SCID-hu mouse: murine model for the analysis of human hematolymphoid differentiation and function

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012844

Severe combined immunodeficiency (SCID) in the mouse. Pathology, reconstitution, neoplasms.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012844

The SCID-hu mouse: a small animal model for HIV infection and pathogenesis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012844

B and T cell leakiness in the scid mouse mutant

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4012844

Development of a human adaptive immune system in cord blood cell-transplanted mice

21 June 2018

1 reference

https://api.crossref.org/works/10.1038%2FCMI.2012.2

Non-obese diabetic-recombination activating gene-1 (NOD-Rag1 null) interleukin (IL)-2 receptor common gamma chain (IL2r gamma null) null mice: a radioresistant model for human lymphohaematopoietic engraftment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCMI.2012.2

Functional human T lymphocyte development from cord blood CD34+ cells in nonobese diabetic/Shi-scid, IL-2 receptor gamma null mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCMI.2012.2

Purified human hematopoietic stem cells contribute to the generation of cardiomyocytes through cell fusion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCMI.2012.2

Spontaneous thymic lymphomas in the non-obese diabetic/Shi-scid, IL-2R gamma (null) mouse.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCMI.2012.2

Early development of human hematopoietic and acquired immune systems in new born NOD/Scid/Jak3null mice intrahepatic engrafted with cord blood-derived CD34 + cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCMI.2012.2

Macrophage tolerance: CD47–SIRP-α–mediated signals matter

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCMI.2012.2

The two faces of the mast cell

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCMI.2012.2

Development of both human connective tissue-type and mucosal-type mast cells in mice from hematopoietic stem cells with identical distribution pattern to human body

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCMI.2012.2

A new humanized mouse model of Epstein-Barr virus infection that reproduces persistent infection, lymphoproliferative disorder, and cell-mediated and humoral immune responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCMI.2012.2

Experimental human challenge infections can accelerate clinical malaria vaccine development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCMI.2012.2

The fate of human peripheral blood lymphocytes after transplantation into SCID mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCMI.2012.2

A new xenograft model for graft-versus-host disease by intravenous transfer of human peripheral blood mononuclear cells in RAG2-/- gammac-/- double-mutant mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCMI.2012.2

Enhanced human cell engraftment in mice deficient in RAG2 and the common cytokine receptor gamma chain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCMI.2012.2

Transfer of a functional human immune system to mice with severe combined immunodeficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCMI.2012.2

Immunodeficient NOD-scid IL-2Rγ(null) mice do not display T and B cell leakiness

21 January 2018

1 reference

12 December 2020

Functional CD5+ B cells develop predominantly in the spleen of NOD/SCID/gammac(null) (NOG) mice transplanted either with human umbilical cord blood, bone marrow, or mobilized peripheral blood CD34+ cells

1 reference

12 December 2020

NOD/LtSz-Rag1nullPfpnull mice: a new model system with increased levels of human peripheral leukocyte and hematopoietic stem-cell engraftment

1 reference

12 December 2020

Infection of the SCID-hu mouse by HIV-1

1 reference

12 December 2020

Enhanced human CD4+ T cell engraftment in beta2-microglobulin-deficient NOD-scid mice

1 reference

12 December 2020

High levels of viremia in hu-PBL-NOD-scid mice with HIV-1 infection

1 reference

12 December 2020

Establishment of a humanized model of liver using NOD/Shi-scid IL2Rgnull mice

1 reference

12 December 2020

Higher susceptibility of NOG mice to xenotransplanted tumors

1 reference

12 December 2020

Highly sensitive model for xenogenic GVHD using severe immunodeficient NOG mice

1 reference

12 December 2020

The analysis of the functions of human B and T cells in humanized NOD/shi-scid/gammac(null) (NOG) mice (hu-HSC NOG mice)

1 reference

12 December 2020

Human peripheral blood leucocyte non-obese diabetic-severe combined immunodeficiency interleukin-2 receptor gamma chain gene mouse model of xenogeneic graft-versus-host-like disease and the role of host major histocompatibility complex

1 reference

12 December 2020

T cell-mediated control of Epstein-Barr virus infection in humanized mice

1 reference

12 December 2020

Identifiers

DOI

10.1038/CMI.2012.2

1 reference

Dimensions Publication ID

28 July 2017

0 references

1 reference

28 July 2017

1 reference