(Q33583983)

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The 3'-untranslated regions of cytoskeletal muscle mRNAs inhibit translation by activating the double-stranded RNA-dependent protein kinase PKR.

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Europe PubMed Central

PubMed publication ID

28 July 2017

The 3'-untranslated regions of cytoskeletal muscle mRNAs inhibit translation by activating the double-stranded RNA-dependent protein kinase PKR. (English)

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

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Jean M Nussbaum

1

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Europe PubMed Central

PubMed publication ID

28 July 2017

Shobha Gunnery

2

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Europe PubMed Central

PubMed publication ID

28 July 2017

Michael B Mathews

3

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Europe PubMed Central

PubMed publication ID

28 July 2017

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1 March 2002

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Europe PubMed Central

PubMed publication ID

28 July 2017

Nucleic Acids Research

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Europe PubMed Central

PubMed publication ID

28 July 2017

30

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Europe PubMed Central

PubMed publication ID

28 July 2017

5

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Europe PubMed Central

PubMed publication ID

28 July 2017

1205-1212

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Europe PubMed Central

PubMed publication ID

28 July 2017

Nuclear factor 90 is a substrate and regulator of the eukaryotic initiation factor 2 kinase double-stranded RNA-activated protein kinase

1 reference

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Straightening of bulged RNA by the double-stranded RNA-binding domain from the protein kinase PKR.

1 reference

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Human breast cancer cells contain elevated levels and activity of the protein kinase, PKR.

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Suppression of neoplastic transformation and regulation of cytoskeleton by tropomyosins

1 reference

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Expanded CUG repeat RNAs form hairpins that activate the double-stranded RNA-dependent protein kinase PKR

1 reference

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DRBP76, a double-stranded RNA-binding nuclear protein, is phosphorylated by the interferon-induced protein kinase, PKR

1 reference

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Nuclear factor-90 of activated T-cells: A double-stranded RNA-binding protein and substrate for the double-stranded RNA-dependent protein kinase, PKR

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Does SINE evolution preclude Alu function?

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Down-regulation of tropomyosin-2 expression in c-Jun-transformed rat fibroblasts involves induction of a MEK1-dependent autocrine loop

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Binding of the protein kinase PKR to RNAs with secondary structure defects: role of the tandem A-G mismatch and noncontiguous helixes

1 reference

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Autophosphorylation in the activation loop is required for full kinase activity in vivo of human and yeast eukaryotic initiation factor 2alpha kinases PKR and GCN2

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Potential Alu function: regulation of the activity of double-stranded RNA-activated kinase PKR.

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21 June 2018

Characterization and mapping of the double-stranded regions involved in activation of PKR within a cellular RNA from 3T3-F442A cells

1 reference

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Analysis of polypeptide expression in benign and malignant human breast lesions

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21 June 2018

Synthesis and purification of single-stranded RNA for use in experiments with PKR and in cell-free translation systems.

1 reference

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The Tat protein of human immunodeficiency virus type 1 is a substrate and inhibitor of the interferon-induced, virally activated protein kinase, PKR

1 reference

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Cytoskeletal and adhesion proteins as tumor suppressors

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Paradoxical interactions between human delta hepatitis agent RNA and the cellular protein kinase PKR

1 reference

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Minor-groove recognition of double-stranded RNA by the double-stranded RNA-binding domain from the RNA-activated protein kinase PKR.

1 reference

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21 June 2018

In vitro activation of the interferon-induced, double-stranded RNA-dependent protein kinase PKR by RNA from the 3' untranslated regions of human alpha-tropomyosin

1 reference

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Genetic complementation reveals a novel regulatory role for 3' untranslated regions in growth and differentiation

1 reference

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21 June 2018

Expression of transduced tropomyosin 1 cDNA suppresses neoplastic growth of cells transformed by the ras oncogene

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Expression, cytoskeletal utilization and dimer formation of tropomyosin derived from retroviral-mediated cDNA transfer. Metabolism of tropomyosin from transduced cDNA.

1 reference

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Modulation of alpha-actinin levels affects cell motility and confers tumorigenicity on 3T3 cells

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Functional characterization of the RNA-binding domain and motif of the double-stranded RNA-dependent protein kinase DAI (PKR).

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Molecular structure and evolutionary origin of human cardiac muscle actin gene

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Double-stranded RNA-dependent protein kinase, PKR, binds preferentially to Huntington's disease (HD) transcripts and is activated in HD tissue

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31 October 2018

Identifiers

10.1093/NAR/30.5.1205

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

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