(Q33588328)

28 July 2017

title

Identification of novel synthetic toll-like receptor 2 agonists by high throughput screening (English)

1 reference

28 July 2017

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Yue Guan

1

1 reference

28 July 2017

Katherine Omueti-Ayoade

2

1 reference

28 July 2017

Sarita K Mutha

3

1 reference

28 July 2017

Paul J Hergenrother

4

1 reference

28 July 2017

Richard I Tapping

5

1 reference

28 July 2017

language of work or name

English

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publication date

26 May 2010

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Journal of Biological Chemistry

28 July 2017

published in

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28 July 2017

volume

285

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28 July 2017

issue

31

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28 July 2017

page(s)

23755-23762

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Human TLRs 10 and 1 share common mechanisms of innate immune sensing but not signaling.

28 July 2017

cites work

1 reference

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Recognition of lipopeptide patterns by Toll-like receptor 2-Toll-like receptor 6 heterodimer

14 July 2018

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Toll-like receptor 2 dependent immunogenicity of glycoconjugate vaccines containing chemically derived zwitterionic polysaccharides

14 July 2018

1 reference

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The potential use of Toll-like receptor (TLR) agonists and antagonists as prophylactic and/or therapeutic agents

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911294

Innate immune sensing and activation of cell surface Toll-like receptors

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911294

Therapeutic targeting of Toll-like receptors for infectious and inflammatory diseases and cancer.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911294

In vivo and in vitro adjuvant activities of the B subunit of Type IIb heat-labile enterotoxin (LT-IIb-B5) from Escherichia coli.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911294

Mapping of a microbial protein domain involved in binding and activation of the TLR2/TLR1 heterodimer

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911294

Structure and regulation of cytoplasmic adapter proteins involved in innate immune signaling

14 July 2018

1 reference

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Engagement of TLR signaling as adjuvant: towards smarter vaccine and beyond

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911294

Structures of the toll-like receptor family and its ligand complexes

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911294

Putting endotoxin to work for us: monophosphoryl lipid A as a safe and effective vaccine adjuvant

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911294

The leucine-rich repeat structure.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911294

Self-adjuvanting lipopeptide vaccines.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911294

The PorB porin from commensal Neisseria lactamica induces Th1 and Th2 immune responses to ovalbumin in mice and is a potential immune adjuvant.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911294

Signaling to NF-kappaB by Toll-like receptors

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911294

Rationally-designed vaccine adjuvants: separating efficacy from toxicity

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911294

Crystal structure of the TLR1-TLR2 heterodimer induced by binding of a tri-acylated lipopeptide

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911294

Robust immune responses elicited by a fully synthetic three-component vaccine

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911294

Recent advances with TLR2-targeting lipopeptide-based vaccines

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911294

Therapeutic targeting of innate immunity with Toll-like receptor agonists and antagonists

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911294

The polymorphism P315L of human toll-like receptor 1 impairs innate immune sensing of microbial cell wall components

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911294

The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911294

Innate immune sensing of pathogens and danger signals by cell surface Toll-like receptors

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911294

Mammalian toll-like receptors: from endogenous ligands to tissue regeneration.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911294

Pathogen recognition and innate immunity

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911294

Toll-like receptor control of the adaptive immune responses

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911294

Human but not murine toll-like receptor 2 discriminates between tri-palmitoylated and tri-lauroylated peptides

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911294

Generating mutant libraries using error-prone PCR.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911294

Cutting edge: role of Toll-like receptor 1 in mediating immune response to microbial lipoproteins

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911294

Discrimination of bacterial lipoproteins by Toll-like receptor 6

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911294

The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between toll-like receptors

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911294

Cell activation and apoptosis by bacterial lipoproteins through toll-like receptor-2

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911294

Host defense mechanisms triggered by microbial lipoproteins through toll-like receptors

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911294

Innate immunity: the virtues of a nonclonal system of recognition

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911294

Seeking wisdom in innate immunity.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911294

Use of bacterial and firefly luciferases as reporter genes in DEAE-dextran-mediated transfection of mammalian cells

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911294

Differential expression and regulation of toll-like receptors (TLR) in human leukocytes: selective expression of TLR3 in dendritic cells

14 July 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.116046

Tissue expression of human Toll-like receptors and differential regulation of Toll-like receptor mRNAs in leukocytes in response to microbes, their products, and cytokines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.116046

Domain exchange between human toll-like receptors 1 and 6 reveals a region required for lipopeptide discrimination

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.116046

TLR1- and TLR6-independent Recognition of Bacterial Lipopeptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.116046

21 January 2018

Identifiers

DOI

10.1074/JBC.M110.116046

1 reference

28 July 2017

1 reference

28 July 2017

1 reference