(Q33598595)

28 July 2017

title

Differences of globin transgene expression in stably transfected cell lines and transgenic mice (English)

1 reference

28 July 2017

Qiliang Li

1

1 reference

28 July 2017

David W Emery

2

1 reference

28 July 2017

Hemei Han

3

1 reference

28 July 2017

Jin Sun

4

1 reference

28 July 2017

Man Yu

5

1 reference

28 July 2017

George Stamatoyannopoulos

6

1 reference

28 July 2017

language of work or name

English

0 references

publication date

30 December 2004

1 reference

28 July 2017

1 reference

28 July 2017

volume

105

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28 July 2017

issue

8

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28 July 2017

page(s)

3346-3352

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28 July 2017

cites work

Locus control regions

1 reference

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Development of virus vectors for gene therapy of beta chain hemoglobinopathies: flanking with a chromatin insulator reduces gamma-globin gene silencing in vivo

21 June 2018

1 reference

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Evidence that DNase I hypersensitive site 5 of the human beta-globin locus control region functions as a chromosomal insulator in transgenic mice

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808413

Developmental specificity of recruitment of TBP to the TATA box of the human gamma-globin gene

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808413

Insulators: many functions, many mechanisms.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808413

Correction of sickle cell disease in transgenic mouse models by gene therapy

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808413

Silencing of gene expression: implications for design of retrovirus vectors

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808413

In vivo silencing of the human gamma-globin gene in murine erythroid cells following retroviral transduction

21 June 2018

1 reference

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Chromatin remodeling in development and differentiation.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808413

Retrovirus vector silencing is de novo methylase independent and marked by a repressive histone code

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808413

A chromatin insulator protects retrovirus vectors from chromosomal position effects

21 June 2018

1 reference

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Therapeutic haemoglobin synthesis in beta-thalassaemic mice expressing lentivirus-encoded human beta-globin

21 June 2018

1 reference

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The genetic program of hematopoietic stem cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808413

Analysis of gamma-globin expression cassettes in retrovirus vectors

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808413

Development of viral vectors for gene therapy of beta-chain hemoglobinopathies: optimization of a gamma-globin gene expression cassette

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808413

Correct function of the locus control region may require passage through a nonerythroid cellular environment.

21 June 2018

1 reference

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Derepression of human embryonic zeta-globin promoter by a locus-control region sequence

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808413

Genetic treatment of severe hemoglobinopathies: the combat against transgene variegation and transgene silencing.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808413

Understanding alpha globin gene expression: a step towards effective gene therapy.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808413

A 5' element of the chicken beta-globin domain serves as an insulator in human erythroid cells and protects against position effect in Drosophila

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808413

Analysis of the human alpha-globin gene cluster in transgenic mice

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808413

Position independence and proper developmental control of gamma-globin gene expression require both a 5' locus control region and a downstream sequence element

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808413

Position-dependent variegation of globin transgene expression in mice

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808413

Contrasting effects of alpha and beta globin regulatory elements on chromatin structure may be related to their different chromosomal environments

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808413

Molecular analysis of the human beta-globin locus activation region

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808413

Characterization of the major regulatory element upstream of the human alpha-globin gene cluster

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808413

Analysis of the human alpha globin upstream regulatory element (HS-40) in transgenic mice

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808413

Successful treatment of murine beta-thalassemia using in vivo selection of genetically modified, drug-resistant hematopoietic stem cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808413

alpha-thalassemia resulting from a negative chromosomal position effect

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808413

Development of a condensed locus control region cassette and testing in retrovirus vectors for A gamma-globin.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808413

Production of genetically stable high-titer retroviral vectors that carry a human gamma-globin gene under the control of the alpha-globin locus control region

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808413

Alpha-thalassemia caused by a large (62 kb) deletion upstream of the human alpha globin gene cluster

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2808413

A major positive regulatory region located far upstream of the human alpha-globin gene locus

30 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15626741

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Immunochemical estimation of haemoglobin types in red blood cells by FACS analysis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15626741

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1182/BLOOD-2004-03-0987

1 reference

28 July 2017

1 reference

28 July 2017

1 reference