(Q33601047)

28 July 2017

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title

The role of homologous recombination processes in the repair of severe forms of DNA damage in mammalian cells (English)

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28 July 2017

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Thacker J

1

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28 July 2017

1 January 1999

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28 July 2017

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28 July 2017

81

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28 July 2017

77-85

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28 July 2017

1-2

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Homologous recombination and the roles of double-strand breaks

28 July 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2899%2980041-8

7 January 2021

Studies of the interaction between Rad52 protein and the yeast single-stranded DNA binding protein RPA.

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2899%2980041-8

7 January 2021

The repair of double-strand breaks in DNA; a model involving recombination

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2899%2980041-8

7 January 2021

The double-strand-break repair model for recombination

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2899%2980041-8

7 January 2021

https://api.crossref.org/works/10.1016%2FS0300-9084%2899%2980041-8

1 reference

7 January 2021

Nucleotide sequence and transcriptional regulation of the yeast recombinational repair gene RAD51

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2899%2980041-8

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2899%2980041-8

7 January 2021

Catalysis of ATP-dependent homologous DNA pairing and strand exchange by yeast RAD51 protein

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2899%2980041-8

7 January 2021

DNA strand exchange mediated by a RAD51-ssDNA nucleoprotein filament with polarity opposite to that of RecA

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2899%2980041-8

7 January 2021

Characterization of strand exchange activity of yeast Rad51 protein

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2899%2980041-8

7 January 2021

Rad51 protein involved in repair and recombination in S. cerevisiae is a RecA-like protein

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2899%2980041-8

7 January 2021

Dominant negative alleles of RAD52 reveal a DNA repair/recombination complex including Rad51 and Rad52.

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2899%2980041-8

7 January 2021

Homotypic and heterotypic protein associations control Rad51 function in double-strand break repair

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2899%2980041-8

7 January 2021

A novel allele of Saccharomyces cerevisiae RFA1 that is deficient in recombination and repair and suppressible by RAD52.

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2899%2980041-8

7 January 2021

DNA strand annealing is promoted by the yeast Rad52 protein

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2899%2980041-8

7 January 2021

Function of yeast Rad52 protein as a mediator between replication protein A and the Rad51 recombinase

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2899%2980041-8

7 January 2021

Stimulation by Rad52 of yeast Rad51-mediated recombination

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2899%2980041-8

7 January 2021

Rad52 protein stimulates DNA strand exchange by Rad51 and replication protein A

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2899%2980041-8

7 January 2021

Direct association between the yeast Rad51 and Rad54 recombination proteins.

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2899%2980041-8

7 January 2021

Recombinational repair in yeast: functional interactions between Rad51 and Rad54 proteins.

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2899%2980041-8

7 January 2021

Complex formation in yeast double-strand break repair: participation of Rad51, Rad52, Rad55, and Rad57 proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2899%2980041-8

7 January 2021

Functional differences and interactions among the putative RecA homologs Rad51, Rad55, and Rad57.

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2899%2980041-8

7 January 2021

Yeast Rad55 and Rad57 proteins form a heterodimer that functions with replication protein A to promote DNA strand exchange by Rad51 recombinase

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2899%2980041-8

7 January 2021

DMC1: a meiosis-specific yeast homolog of E. coli recA required for recombination, synaptonemal complex formation, and cell cycle progression

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2899%2980041-8

7 January 2021

A Rad52 homolog is required for RAD51-independent mitotic recombination in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2899%2980041-8

7 January 2021

Cloning the RAD51 homologue of Schizosaccharomyces pombe.

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2899%2980041-8

7 January 2021

SENSITIVITY TO PHOTOADDITION OF MONO-AND BIFUNCTIONAL FUROCOUMARINS OF X-RAY SENSITIVE MUTANTS OF SACCHAROMYCES CEREVISIAE

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2899%2980041-8

7 January 2021

Further characterization of the yeast pso4-1 mutant: interaction with rad51 and rad52 mutants after photoinduced psoralen lesions

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2899%2980041-8

7 January 2021

Effect of double-strand breaks on homologous recombination in mammalian cells and extracts

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2899%2980041-8

7 January 2021

Promotion of double-strand break repair by human nuclear extracts preferentially involves recombination with intact homologous DNA

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2899%2980041-8

7 January 2021

Gene recombination in X-ray-sensitive hamster cells

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2899%2980041-8

7 January 2021

Menage à trois: double strand break repair, V(D)J recombination and DNA-PK.

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2899%2980041-8

7 January 2021

Mutant rodent cell lines sensitive to ultraviolet light, ionizing radiation and cross-linking agents: a comprehensive survey of genetic and biochemical characteristics

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2899%2980041-8

7 January 2021

The genetic basis of resistance to ionising radiation damage in cultured mammalian cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2899%2980041-8

7 January 2021

Genetic analysis of ionising radiation sensitive mutants of cultured mammalian cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2899%2980041-8

7 January 2021

Interspecific complementation between mouse and Chinese hamster cell mutants hypersensitive to ionizing radiation

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2899%2980041-8

7 January 2021

Genetic analysis of mitomycin C-hypersensitive Chinese hamster cell mutants

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2899%2980041-8

7 January 2021

Gene mutation and V(D)J recombination in the radiosensitive irs lines

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2899%2980041-8

7 January 2021

Cytogenetic characterization of the ionizing radiation-sensitive Chinese hamster mutant irs1.

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2899%2980041-8

7 January 2021

Increased frequency of formation of interphase ring-chromosomes in radiosensitive irs-1 cells exposed to X-rays

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2899%2980041-8

7 January 2021

Localization to chromosome 7q36.1 of the human XRCC2 gene, determining sensitivity to DNA-damaging agents

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2899%2980041-8

7 January 2021

Assignment of the XRCC2 human DNA repair gene to chromosome 7q36 by complementation analysis

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2899%2980041-8

7 January 2021

The XRCC2 DNA repair gene: identification of a positional candidate

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2899%2980041-8

7 January 2021

The XRCC2 DNA repair gene from human and mouse encodes a novel member of the recA/RAD51 family

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2899%2980041-8

7 January 2021

XRCC2 and XRCC3, new human Rad51-family members, promote chromosome stability and protect against DNA cross-links and other damages

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2899%2980041-8

7 January 2021

Cross-sensitivity of gamma-ray-sensitive hamster mutants to cross-linking agents

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2899%2980041-8

7 January 2021

Correction of chromosomal instability and sensitivity to diverse mutagens by a cloned cDNA of the XRCC3 DNA repair gene

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2899%2980041-8

7 January 2021

Basic local alignment search tool

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2899%2980041-8

7 January 2021

Isolation of novel human and mouse genes of the recA/RAD51 recombination-repair gene family

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2899%2980041-8

7 January 2021

Isolation of human and mouse genes based on homology to REC2, a recombinational repair gene from the fungus Ustilago maydis

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2899%2980041-8

7 January 2021

Identification of a novel human RAD51 homolog, RAD51B

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2899%2980041-8

7 January 2021

Isolation and characterization of RAD51C, a new human member of the RAD51 family of related genes

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2899%2980041-8

7 January 2021

Identification, characterization, and genetic mapping of Rad51d, a new mouse and human RAD51/RecA-related gene

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2899%2980041-8

7 January 2021

A mouse homolog of the Escherichia coli recA and Saccharomyces cerevisiae RAD51 genes

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2899%2980041-8

7 January 2021

Cloning of human, mouse and fission yeast recombination genes homologous to RAD51 and recA

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2899%2980041-8

7 January 2021

Cloning and sequence of the human RecA-like gene cDNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2899%2980041-8

7 January 2021

Characterization of a mouse recA-like gene specifically expressed in testis

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2899%2980041-8

7 January 2021

The mouse and human homologs of DMC1, the yeast meiosis-specific homologous recombination gene, have a common unique form of exon-skipped transcript in meiosis

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2899%2980041-8

7 January 2021

Purification and characterization of the human Rad51 protein, an analogue of E. coli RecA

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2899%2980041-8

7 January 2021

Human Rad51 protein promotes ATP-dependent homologous pairing and strand transfer reactions in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2899%2980041-8

7 January 2021

Activities of human recombination protein Rad51.

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2899%2980041-8

7 January 2021

The human Rad51 protein: polarity of strand transfer and stimulation by hRP-A.

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2899%2980041-8

7 January 2021

Physical interaction between human RAD52 and RPA is required for homologous recombination in mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2899%2980041-8

7 January 2021

Synergistic actions of Rad51 and Rad52 in recombination and DNA repair.

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2899%2980041-8

7 January 2021

Nuclear foci of mammalian Rad51 recombination protein in somatic cells after DNA damage and its localization in synaptonemal complexes

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2899%2980041-8

7 January 2021

Distribution of the Rad51 recombinase in human and mouse spermatocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2899%2980041-8

7 January 2021

Cell cycle-dependent protein expression of mammalian homologs of yeast DNA double-strand break repair genes Rad51 and Rad52

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2899%2980041-8

7 January 2021

Overexpression of Rad51 protein stimulates homologous recombination and increases resistance of mammalian cells to ionizing radiation

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2899%2980041-8

7 January 2021

Targeted disruption of the Rad51 gene leads to lethality in embryonic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2899%2980041-8

7 January 2021

A mutation in mouse rad51 results in an early embryonic lethal that is suppressed by a mutation in p53

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2899%2980041-8

7 January 2021

Relating biochemistry to biology: how the recombinational repair function of RecA protein is manifested in its molecular properties

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2899%2980041-8

7 January 2021

Meiotic prophase arrest with failure of chromosome synapsis in mice deficient for Dmc1, a germline-specific RecA homolog

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2899%2980041-8

7 January 2021

The mouse RecA-like gene Dmc1 is required for homologous chromosome synapsis during meiosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2899%2980041-8

7 January 2021

Rad51-deficient vertebrate cells accumulate chromosomal breaks prior to cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2899%2980041-8

7 January 2021

p53 is linked directly to homologous recombination processes via RAD51/RecA protein interaction

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2899%2980041-8

7 January 2021

Interaction of p53 with the human Rad51 protein

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2899%2980041-8

7 January 2021

Association of BRCA1 with Rad51 in mitotic and meiotic cells

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2899%2980041-8

7 January 2021

RAB22 and RAB163/mouse BRCA2: proteins that specifically interact with the RAD51 protein

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2899%2980041-8

7 January 2021

Embryonic lethality and radiation hypersensitivity mediated by Rad51 in mice lacking Brca2

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2899%2980041-8

7 January 2021

Holliday junctions accumulate in replication mutants via a RecA homolog-independent mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2899%2980041-8

7 January 2021

Loss of S-phase-dependent radioresistance in irs-1 cells exposed to X-rays

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2899%2980041-8

7 January 2021

A mechanism for deletion formation in DNA by human cell extracts: the involvement of short sequence repeats

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2899%2980041-8

7 January 2021

Formation and stability of interstrand cross-links induced by cis- and trans-diamminedichloroplatinum (II) in the DNA of Saccharomyces cerevisiae strains differing in repair capacity

1 reference

https://api.crossref.org/works/10.1016%2FS0300-9084%2899%2980041-8

7 January 2021

10.1016/S0300-9084(99)80041-8

Identifiers

DOI

1 reference

28 July 2017

1 reference

PubMed ID

10214913