(Q33606240)

28 July 2017

title

Sensing a sensor: identifying the mechanosensory function of primary cilia (English)

1 reference

28 July 2017

1 reference

Rahul M Prasad

1

1 reference

28 July 2017

Xingjian Jin

series ordinal

2

1 reference

28 July 2017

Surya M Nauli

series ordinal

3

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28 July 2017

publication date

1 March 2014

1 reference

28 July 2017

1 reference

28 July 2017

volume

4

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28 July 2017

issue

1

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28 July 2017

page(s)

47-62

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Creative Commons Attribution 4.0 International

28 July 2017

copyright license

start time

13 March 2014

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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Primary cilia are specialized calcium signalling organelles

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21 June 2018

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21 June 2018

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Genetically encoded calcium indicator illuminates calcium dynamics in primary cilia.

21 June 2018

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21 June 2018

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Increased Na+/H+ exchanger activity on the apical surface of a cilium-deficient cortical collecting duct principal cell model of polycystic kidney disease

21 June 2018

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The primary cilium as a dual sensor of mechanochemical signals in chondrocytes

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Culturing pancreatic islets in microfluidic flow enhances morphology of the associated endothelial cells

21 June 2018

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Dopamine receptor type 5 in the primary cilia has dual chemo- and mechano-sensory roles

21 June 2018

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Primary cilia regulate mTORC1 activity and cell size through Lkb1.

21 June 2018

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Direct demonstration of tubular fluid flow sensing by macula densa cells

21 June 2018

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Planar cell polarity breaks bilateral symmetry by controlling ciliary positioning

21 June 2018

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Somatostatin signaling in neuronal cilia is critical for object recognition memory.

21 June 2018

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Human retinopathy-associated ciliary protein retinitis pigmentosa GTPase regulator mediates cilia-dependent vertebrate development

21 June 2018

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Depletion of selenoprotein GPx4 in spermatocytes causes male infertility in mice

21 June 2018

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A novel mouse model reveals that polycystin-1 deficiency in ependyma and choroid plexus results in dysfunctional cilia and hydrocephalus.

21 June 2018

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Primary cilia can both mediate and suppress Hedgehog pathway-dependent tumorigenesis

21 June 2018

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Dual and opposing roles of primary cilia in medulloblastoma development

21 June 2018

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Motile cilia of human airway epithelia are chemosensory

21 June 2018

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Defects in neural stem cell proliferation and olfaction in Chd7 deficient mice indicate a mechanism for hyposmia in human CHARGE syndrome

21 June 2018

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Ciliary polycystin-2 is a mechanosensitive calcium channel involved in nitric oxide signaling cascades

21 June 2018

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The primary cilium coordinates signaling pathways in cell cycle control and migration during development and tissue repair

21 June 2018

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Overexpression of RPGR leads to male infertility in mice due to defects in flagellar assembly

21 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019930

Role of cilia, mucus, and airway surface liquid in mucociliary dysfunction: lessons from mouse models

21 June 2018

1 reference

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The primary cilium as a gravitational force transducer and a regulator of transcriptional noise

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019930

Endothelial cilia are fluid shear sensors that regulate calcium signaling and nitric oxide production through polycystin-1

21 June 2018

1 reference

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Primary ciliary dyskinesia in mice lacking the novel ciliary protein Pcdp1.

21 June 2018

1 reference

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Disruption of intraflagellar transport in adult mice leads to obesity and slow-onset cystic kidney disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019930

Primary cilia mediate mechanosensing in bone cells by a calcium-independent mechanism.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019930

Ciliary calcium signaling is modulated by kidney injury molecule-1 (Kim1)

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019930

Genetic defects in ciliary structure and function

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019930

Cholangiocyte cilia detect changes in luminal fluid flow and transmit them into intracellular Ca2+ and cAMP signaling

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019930

Regulation of mammalian ciliary beating.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019930

Cilia-like structures and polycystin-1 in osteoblasts/osteocytes and associated abnormalities in skeletogenesis and Runx2 expression.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019930

The reproductive significance of human Fallopian tube cilia

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019930

Lack of a laterality phenotype in Pkd1 knock-out embryos correlates with absence of polycystin-1 in nodal cilia

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019930

The C. elegans homologs of nephrocystin-1 and nephrocystin-4 are cilia transition zone proteins involved in chemosensory perception

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019930

RPGR is mutated in patients with a complex X linked phenotype combining primary ciliary dyskinesia and retinitis pigmentosa

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019930

Subcellular localization of ALMS1 supports involvement of centrosome and basal body dysfunction in the pathogenesis of obesity, insulin resistance, and type 2 diabetes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019930

TRPV4 channel is involved in the coupling of fluid viscosity changes to epithelial ciliary activity

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019930

Bbs2-null mice have neurosensory deficits, a defect in social dominance, and retinopathy associated with mislocalization of rhodopsin

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019930

Loss of BBS proteins causes anosmia in humans and defects in olfactory cilia structure and function in the mouse

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019930

Two populations of node monocilia initiate left-right asymmetry in the mouse

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019930

Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019930

Bending the MDCK cell primary cilium increases intracellular calcium

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019930

A three-dimensional distribution of osteocyte processes revealed by the combination of confocal laser scanning microscopy and differential interference contrast microscopy

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019930

Randomization of left-right asymmetry due to loss of nodal cilia generating leftward flow of extraembryonic fluid in mice lacking KIF3B motor protein

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019930

Anatomy and physiology of the fallopian tube.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019930

MAP kinase and calcium signaling mediate fluid flow-induced human mesenchymal stem cell proliferation

21 June 2018

1 reference

https://api.crossref.org/works/10.3390%2FBIOS4010047

Conserved function for embryonic nodal cilia.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FBIOS4010047

Primary cilia deletion in pancreatic epithelial cells results in cyst formation and pancreatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FBIOS4010047

Survivin-induced abnormal ploidy contributes to cystic kidney and aneurysm formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FBIOS4010047

Localization of the angiopoietin receptors Tie-1 and Tie-2 on the primary cilia in the female reproductive organs

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FBIOS4010047

New neurons follow the flow of cerebrospinal fluid in the adult brain

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FBIOS4010047

Effect of flow and stretch on the [Ca2+]i response of principal and intercalated cells in cortical collecting duct

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FBIOS4010047

Loss of primary cilia results in deregulated and unabated apical calcium entry in ARPKD collecting duct cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FBIOS4010047

Ex vivo real-time observation of Ca(2+) signaling in living bone in response to shear stress applied on the bone surface.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FBIOS4010047

Effects of luminal flow and nucleotides on [Ca(2+)](i) in rabbit cortical collecting duct

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FBIOS4010047

FGF-induced vesicular release of Sonic hedgehog and retinoic acid in leftward nodal flow is critical for left-right determination.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FBIOS4010047

Loss of Polycystin-1 in Human Cyst-Lining Epithelia Leads to Ciliary Dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FBIOS4010047

Endothelial primary cilia in areas of disturbed flow are at the base of atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FBIOS4010047

Determination of left–right patterning of the mouse embryo by artificial nodal flow

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FBIOS4010047

Articular cartilage and growth plate defects are associated with chondrocyte cytoskeletal abnormalities in Tg737orpk mice lacking the primary cilia protein polaris

21 January 2018

1 reference

12 December 2020

Enhanced osteogenesis of human alveolar bone-derived mesenchymal stem cells for tooth tissue engineering using fluid shear stress in a rocking culture method

1 reference

12 December 2020

Landmarks in the first hundred years of primary (9+0) cilium research

1 reference

12 December 2020

In situ imaging of the autonomous intracellular Ca(2+) oscillations of osteoblasts and osteocytes in bone

1 reference

12 December 2020

Shear stress-induced Ca²⁺ mobilization in MDCK cells is ATP dependent, no matter the primary cilium

1 reference

12 December 2020

Dysfunction of axonemal dynein heavy chain Mdnah5 inhibits ependymal flow and reveals a novel mechanism for hydrocephalus formation

1 reference

12 December 2020

Identifiers

DOI

10.3390/BIOS4010047

1 reference

28 July 2017

1 reference

28 July 2017

1 reference