(Q33630981)

28 July 2017

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title

Molecular mimicry and multiple sclerosis: degenerate T-cell recognition and the induction of autoimmunity (English)

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ORCID Public Data File 2021

28 July 2017

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author name string

Gran B

1

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28 July 2017

Hemmer B

2

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28 July 2017

Vergelli M

3

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28 July 2017

McFarland HF

4

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28 July 2017

Martin R

5

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28 July 2017

language of work or name

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1 May 1999

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28 July 2017

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28 July 2017

45

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28 July 2017

559-567

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28 July 2017

5

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Immunological aspects of demyelinating diseases

28 July 2017

1 reference

https://api.crossref.org/works/10.1002%2F1531-8249%28199905%2945%3A5%3C559%3A%3AAID-ANA3%3E3.0.CO%3B2-Q

Amino acid homology between the encephalitogenic site of myelin basic protein and virus: mechanism for autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1531-8249%28199905%2945%3A5%3C559%3A%3AAID-ANA3%3E3.0.CO%3B2-Q

Gamma delta T cell receptor repertoire in brain lesions of patients with multiple sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1531-8249%28199905%2945%3A5%3C559%3A%3AAID-ANA3%3E3.0.CO%3B2-Q

Patients with multiple sclerosis carry DQB1 genes which encode shared polymorphic amino acid sequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1531-8249%28199905%2945%3A5%3C559%3A%3AAID-ANA3%3E3.0.CO%3B2-Q

Takayasu's Disease: Association with HLA-B5

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1531-8249%28199905%2945%3A5%3C559%3A%3AAID-ANA3%3E3.0.CO%3B2-Q

A genome screen in multiple sclerosis reveals susceptibility loci on chromosome 6p21 and 17q22

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1531-8249%28199905%2945%3A5%3C559%3A%3AAID-ANA3%3E3.0.CO%3B2-Q

Interferon beta-1b is effective in relapsing-remitting multiple sclerosis. II. MRI analysis results of a multicenter, randomized, double-blind, placebo-controlled trial. UBC MS/MRI Study Group and the IFNB Multiple Sclerosis Study Group

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1531-8249%28199905%2945%3A5%3C559%3A%3AAID-ANA3%3E3.0.CO%3B2-Q

Treatment of multiple sclerosis with gamma interferon: exacerbations associated with activation of the immune system

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1531-8249%28199905%2945%3A5%3C559%3A%3AAID-ANA3%3E3.0.CO%3B2-Q

Distinct patterns of multiple sclerosis pathology indicates heterogeneity on pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1531-8249%28199905%2945%3A5%3C559%3A%3AAID-ANA3%3E3.0.CO%3B2-Q

Isolation of myelin basic protein-reactive T-cell lines from normal human blood

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1531-8249%28199905%2945%3A5%3C559%3A%3AAID-ANA3%3E3.0.CO%3B2-Q

Myelin basic protein‐specific T lymphocyte lines from MS patients and healthy individuals

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1531-8249%28199905%2945%3A5%3C559%3A%3AAID-ANA3%3E3.0.CO%3B2-Q

Increased frequency of interleukin 2-responsive T cells specific for myelin basic protein and proteolipid protein in peripheral blood and cerebrospinal fluid of patients with multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1531-8249%28199905%2945%3A5%3C559%3A%3AAID-ANA3%3E3.0.CO%3B2-Q

Clinical viral infections and multiple sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1531-8249%28199905%2945%3A5%3C559%3A%3AAID-ANA3%3E3.0.CO%3B2-Q

Epidemiologic evidence for multiple sclerosis as an infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1531-8249%28199905%2945%3A5%3C559%3A%3AAID-ANA3%3E3.0.CO%3B2-Q

Myelin basic protein and human coronavirus 229E cross-reactive T cells in multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1531-8249%28199905%2945%3A5%3C559%3A%3AAID-ANA3%3E3.0.CO%3B2-Q

Restriction of in vitro T cell-mediated cytotoxicity in lymphocytic choriomeningitis within a syngeneic or semiallogeneic system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1531-8249%28199905%2945%3A5%3C559%3A%3AAID-ANA3%3E3.0.CO%3B2-Q

MHC-dependent antigen processing and peptide presentation: providing ligands for T lymphocyte activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1531-8249%28199905%2945%3A5%3C559%3A%3AAID-ANA3%3E3.0.CO%3B2-Q

Activation of naive, memory and effector T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1531-8249%28199905%2945%3A5%3C559%3A%3AAID-ANA3%3E3.0.CO%3B2-Q

Cytokine-producing cells in experimental autoimmune encephalomyelitis and multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1531-8249%28199905%2945%3A5%3C559%3A%3AAID-ANA3%3E3.0.CO%3B2-Q

Molecular mimicry: can epitope mimicry induce autoimmune disease?

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1531-8249%28199905%2945%3A5%3C559%3A%3AAID-ANA3%3E3.0.CO%3B2-Q

Promiscuous and allele-specific anchors in HLA-DR-binding peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1531-8249%28199905%2945%3A5%3C559%3A%3AAID-ANA3%3E3.0.CO%3B2-Q

Structural basis for T cell recognition of altered peptide ligands: a single T cell receptor can productively recognize a large continuum of related ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1531-8249%28199905%2945%3A5%3C559%3A%3AAID-ANA3%3E3.0.CO%3B2-Q

Structural requirements for binding of an immunodominant myelin basic protein peptide to DR2 isotypes and for its recognition by human T cell clones

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1531-8249%28199905%2945%3A5%3C559%3A%3AAID-ANA3%3E3.0.CO%3B2-Q

Molecular mimicry in T cell-mediated autoimmunity: viral peptides activate human T cell clones specific for myelin basic protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1531-8249%28199905%2945%3A5%3C559%3A%3AAID-ANA3%3E3.0.CO%3B2-Q

Complementary mutations in an antigenic peptide allow for crossreactivity of autoreactive T-cell clones

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1531-8249%28199905%2945%3A5%3C559%3A%3AAID-ANA3%3E3.0.CO%3B2-Q

Generation and use of synthetic peptide combinatorial libraries for basic research and drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1531-8249%28199905%2945%3A5%3C559%3A%3AAID-ANA3%3E3.0.CO%3B2-Q

Decrypting the structure of major histocompatibility complex class I-restricted cytotoxic T lymphocyte epitopes with complex peptide libraries

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1531-8249%28199905%2945%3A5%3C559%3A%3AAID-ANA3%3E3.0.CO%3B2-Q

Probing degeneracy in T-cell recognition using peptide combinatorial libraries

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1531-8249%28199905%2945%3A5%3C559%3A%3AAID-ANA3%3E3.0.CO%3B2-Q

Identification of high potency microbial and self ligands for a human autoreactive class II-restricted T cell clone

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1531-8249%28199905%2945%3A5%3C559%3A%3AAID-ANA3%3E3.0.CO%3B2-Q

Altered peptide ligand-induced partial T cell activation: molecular mechanisms and role in T cell biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1531-8249%28199905%2945%3A5%3C559%3A%3AAID-ANA3%3E3.0.CO%3B2-Q

The shaping of the brain-specific T lymphocyte repertoire in the thymus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1531-8249%28199905%2945%3A5%3C559%3A%3AAID-ANA3%3E3.0.CO%3B2-Q

Negative selection of lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1531-8249%28199905%2945%3A5%3C559%3A%3AAID-ANA3%3E3.0.CO%3B2-Q

Positive selection of lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1531-8249%28199905%2945%3A5%3C559%3A%3AAID-ANA3%3E3.0.CO%3B2-Q

Evidence for a differential avidity model of T cell selection in the thymus

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1531-8249%28199905%2945%3A5%3C559%3A%3AAID-ANA3%3E3.0.CO%3B2-Q

A differential-avidity model for T-cell selection

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1531-8249%28199905%2945%3A5%3C559%3A%3AAID-ANA3%3E3.0.CO%3B2-Q

Endogenous peptides associated with MHC class II and selection of CD4 T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1531-8249%28199905%2945%3A5%3C559%3A%3AAID-ANA3%3E3.0.CO%3B2-Q

Expression of autoimmune disease-related antigens by cells of the immune system

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1531-8249%28199905%2945%3A5%3C559%3A%3AAID-ANA3%3E3.0.CO%3B2-Q

The role of the thymus in the control of autoimmunity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1531-8249%28199905%2945%3A5%3C559%3A%3AAID-ANA3%3E3.0.CO%3B2-Q

Mechanisms of tolerance induction in major histocompatibility complex class II-restricted T cells specific for a blood-borne self-antigen.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1531-8249%28199905%2945%3A5%3C559%3A%3AAID-ANA3%3E3.0.CO%3B2-Q

In thymic selection, peptide diversity gives and takes away

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1531-8249%28199905%2945%3A5%3C559%3A%3AAID-ANA3%3E3.0.CO%3B2-Q

The repertoire of T cells shaped by a single MHC/peptide ligand.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1531-8249%28199905%2945%3A5%3C559%3A%3AAID-ANA3%3E3.0.CO%3B2-Q

Specific recognition of thymic self-peptides induces the positive selection of cytotoxic T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1531-8249%28199905%2945%3A5%3C559%3A%3AAID-ANA3%3E3.0.CO%3B2-Q

Peripheral T cell survival requires continual ligation of the T cell receptor to major histocompatibility complex-encoded molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1531-8249%28199905%2945%3A5%3C559%3A%3AAID-ANA3%3E3.0.CO%3B2-Q

On the presence of Ia-positive endothelial cells and astrocytes in multiple sclerosis lesions and its relevance to antigen presentation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1531-8249%28199905%2945%3A5%3C559%3A%3AAID-ANA3%3E3.0.CO%3B2-Q

Diabetes induced by Coxsackie virus: initiation by bystander damage and not molecular mimicry

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1531-8249%28199905%2945%3A5%3C559%3A%3AAID-ANA3%3E3.0.CO%3B2-Q

Viral infection of transgenic mice expressing a viral protein in oligodendrocytes leads to chronic central nervous system autoimmune disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1531-8249%28199905%2945%3A5%3C559%3A%3AAID-ANA3%3E3.0.CO%3B2-Q

Endogenous myelin basic protein inactivates the high avidity T cell repertoire

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1531-8249%28199905%2945%3A5%3C559%3A%3AAID-ANA3%3E3.0.CO%3B2-Q

Multiple sclerosis: oligodendrocytes in active lesions do not express class II major histocompatibility complex molecules.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1531-8249%28199905%2945%3A5%3C559%3A%3AAID-ANA3%3E3.0.CO%3B2-Q

Ablation of "tolerance" and induction of diabetes by virus infection in viral antigen transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1531-8249%28199905%2945%3A5%3C559%3A%3AAID-ANA3%3E3.0.CO%3B2-Q

Virus infection triggers insulin-dependent diabetes mellitus in a transgenic model: role of anti-self (virus) immune response

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1531-8249%28199905%2945%3A5%3C559%3A%3AAID-ANA3%3E3.0.CO%3B2-Q

The virology of demyelinating diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1531-8249%28199905%2945%3A5%3C559%3A%3AAID-ANA3%3E3.0.CO%3B2-Q

Endothelial-leukocyte adhesion molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1531-8249%28199905%2945%3A5%3C559%3A%3AAID-ANA3%3E3.0.CO%3B2-Q

Spreading of T-cell autoimmunity to cryptic determinants of an autoantigen

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1531-8249%28199905%2945%3A5%3C559%3A%3AAID-ANA3%3E3.0.CO%3B2-Q

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1531-8249%28199905%2945%3A5%3C559%3A%3AAID-ANA3%3E3.0.CO%3B2-Q

A full genome search in multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1531-8249%28199905%2945%3A5%3C559%3A%3AAID-ANA3%3E3.0.CO%3B2-Q

T-cell recognition of an immuno-dominant myelin basic protein epitope in multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F1531-8249%28199905%2945%3A5%3C559%3A%3AAID-ANA3%3E3.0.CO%3B2-Q

Intrathymic expression of genes involved in organ specific autoimmune disease

21 January 2018

1 reference

12 December 2020

Separation of T helper 1 clone cytolysis from proliferation and lymphokine production using analog peptides

1 reference

12 December 2020

Predictable TCR antigen recognition based on peptide scans leads to the identification of agonist ligands with no sequence homology

1 reference

12 December 2020

Multiple sclerosis☆Distribution of T cells, T cell subsets and Ia-positive macrophages in lesions of different ages

1 reference

12 December 2020

Modifications of peptide ligands enhancing T cell responsiveness imply large numbers of stimulatory ligands for autoreactive T cells

1 reference

12 December 2020

The costimulatory molecule B7 is expressed on human microglia in culture and in multiple sclerosis acute lesions.

1 reference

12 December 2020

Thymic expression of autoantigens correlates with resistance to autoimmune disease

1 reference

12 December 2020

Fine specificity and HLA restriction of myelin basic protein-specific cytotoxic T cell lines from multiple sclerosis patients and healthy individuals

1 reference

12 December 2020

Naive and effector CD4 T cells differ in their requirements for T cell receptor versus costimulatory signals

1 reference

12 December 2020

Thymic expression of myelin basic protein (MBP). Activation of MBP-specific T cells by thymic cells in the absence of exogenous MBP

1 reference

12 December 2020

Interferon beta-1b is effective in relapsing-remitting multiple sclerosis. I. Clinical results of a multicenter, randomized, double-blind, placebo-controlled trial. The IFNB Multiple Sclerosis Study Group

1 reference

12 December 2020

Multiple sclerosis: a quantitative and qualitative study of immunoglobulin-containing cells in the central nervous system

1 reference

12 December 2020

Transcription of a broad range of self-antigens in human thymus suggests a role for central mechanisms in tolerance toward peripheral antigens

1 reference

12 December 2020

A very high level of crossreactivity is an essential feature of the T-cell receptor

1 reference

12 December 2020

Ligand motifs of HLA-DRB5*0101 and DRB1*1501 molecules delineated from self-peptides

1 reference

12 December 2020

Intermittent cyclophosphamide pulse therapy in progressive multiple sclerosis: final report of the Northeast Cooperative Multiple Sclerosis Treatment Group

1 reference

12 December 2020

Self-nonself discrimination by T cells

1 reference

12 December 2020

Differential activation of human autoreactive T cell clones by altered peptide ligands derived from myelin basic protein peptide (87-99)

1 reference

12 December 2020

A complete genomic screen for multiple sclerosis underscores a role for the major histocompatability complex. The Multiple Sclerosis Genetics Group

1 reference

12 December 2020

Sardinian multiple sclerosis is associated with HLA-DR4: a serologic and molecular analysis

1 reference

12 December 2020

1 reference

12 December 2020

A cartilage-mimicking T-cell epitope on a 65K mycobacterial heat-shock protein: adjuvant arthritis as a model for human rheumatoid arthritis

1 reference

12 December 2020

Molecular mimicry and autoimmune disease

1 reference

12 December 2020

Estimation of the frequency of self-reactive T cells in health and inflammatory diseases by limiting dilution analysis and single cell cloning

1 reference

12 December 2020

Influence of infection on exacerbations of multiple sclerosis

1 reference

12 December 2020

A viral peptide with limited homology to a self peptide can induce clinical signs of experimental autoimmune encephalomyelitis.

1 reference

12 December 2020

Autoaggressive T lymphocyte lines recognizing the encephalitogenic region of myelin basic protein: in vitro selection from unprimed rat T lymphocyte populations

1 reference

12 December 2020

An autoantigenic T cell epitope forms unstable complexes with class II MHC: a novel route for escape from tolerance induction

1 reference

12 December 2020

1 reference

12 December 2020

The 2H4 (CD45R) antigen is selectively decreased in multiple sclerosis lesions

1 reference

12 December 2020

1 reference

12 December 2020

Major histocompatibility complex-linked control of the murine immune response to myelin basic protein.

1 reference

12 December 2020

1 reference

12 December 2020

Separation of IL-4 production from Th cell proliferation by an altered T cell receptor ligand

1 reference

12 December 2020

Relationships among TCR ligand potency, thresholds for effector function elicitation, and the quality of early signaling events in human T cells.

1 reference

12 December 2020

10.1002/1531-8249(199905)45:5<559::AID-ANA3>3.0.CO;2-Q

Identifiers

DOI

1 reference

28 July 2017

1 reference