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Mechanism of action of P-glycoprotein in relation to passive membrane permeation.
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
10331240
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10331240%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 December 2019
review article
1 reference
stated in
Europe PubMed Central
title
Mechanism of action of P-glycoprotein in relation to passive membrane permeation
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
10331240
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10331240%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 December 2019
author name string
G D Eytan
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
10331240
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10331240%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 December 2019
P W Kuchel
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed ID
10331240
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10331240%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 December 2019
publication date
1 January 1999
1 reference
stated in
Europe PubMed Central
PubMed ID
10331240
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10331240%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 December 2019
number of pages
76
1 reference
based on heuristic
inferred from page(s)
published in
International Review of Cytology
1 reference
stated in
Europe PubMed Central
PubMed ID
10331240
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10331240%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 December 2019
volume
190
1 reference
stated in
Europe PubMed Central
PubMed ID
10331240
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10331240%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 December 2019
page(s)
175-250
1 reference
stated in
Europe PubMed Central
PubMed ID
10331240
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10331240%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 December 2019
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Relation between the turnover number for vinblastine transport and for vinblastine-stimulated ATP hydrolysis by human P-glycoprotein
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Partial purification and reconstitution of the human multidrug-resistance pump: characterization of the drug-stimulatable ATP hydrolysis
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The gene encoding multidrug resistance is induced and expressed at high levels during pregnancy in the secretory epithelium of the uterus
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Probing the interaction of the multidrug-resistance phenotype with the polypeptide ionophore gramicidin D via functional channel formation
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7 January 2021
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Co-operative, competitive and non-competitive interactions between modulators of P-glycoprotein
1 reference
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7 January 2021
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Clinical reversal of multidrug resistance
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Functional dissection of P-glycoprotein nucleotide-binding domains in chimeric and mutant proteins. Modulation of drug resistance profiles
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7 January 2021
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Kinetic analysis of carrier-mediated ion transport by the charge-pulse technique
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Reconstitution of a bacterial periplasmic permease in proteoliposomes and demonstration of ATP hydrolysis concomitant with transport
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7 January 2021
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Multidrug resistance in Lactococcus lactis: evidence for ATP-dependent drug extrusion from the inner leaflet of the cytoplasmic membrane.
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7 January 2021
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Competition of hydrophobic peptides, cytotoxic drugs, and chemosensitizers on a common P-glycoprotein pharmacophore as revealed by its ATPase activity
1 reference
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7 January 2021
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Analysis of drug transport kinetics in multidrug-resistant cells using a novel coumarin-vinblastine compound
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7 January 2021
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Mobile ionophores are a novel class of P-glycoprotein inhibitors. The effects of ionophores on 4'-O-tetrahydropyranyl-adriamycin incorporation in K562 drug-resistant cells
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7 January 2021
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The blood-brain barrier. Transport across the cerebral endothelium
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7 January 2021
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Structural basis of anthracycline selectivity for unilamellar phosphatidylcholine vesicles: an equilibrium binding study
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7 January 2021
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Fast kinetic analysis of drug transport in multidrug resistant cells using a pulsed quench-flow apparatus
1 reference
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7 January 2021
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Reversal of multidrug resistance
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7 January 2021
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Multidrug-resistant human sarcoma cells with a mutant P-glycoprotein, altered phenotype, and resistance to cyclosporins.
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7 January 2021
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Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line
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7 January 2021
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Multidrug resistance-associated protein: sequence correction.
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7 January 2021
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Interaction of N-alkylanthracyclines with lipid bilayers: correlations between partition coefficients, lipid phase distributions and thermotropic behavior
1 reference
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7 January 2021
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inferred from DOI database lookup
Expression of the multidrug resistance gene product (P-glycoprotein) in human normal and tumor tissues.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962148-8
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7 January 2021
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inferred from DOI database lookup
Membrane vesicles from multidrug-resistant human cancer cells contain a specific 150- to 170-kDa protein detected by photoaffinity labeling
1 reference
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Crossref
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7 January 2021
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Characteristics of doxorubicin transport in human red blood cells
1 reference
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Crossref
reference URL
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7 January 2021
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A model for computer simulation of P-glycoprotein and transmembrane delta pH-mediated anthracycline transport in multidrug-resistant tumor cells
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962148-8
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7 January 2021
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Two members of the mouse mdr gene family confer multidrug resistance with overlapping but distinct drug specificities
1 reference
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Crossref
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7 January 2021
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Characterization of the interaction of doxorubicin with (poly)phosphoinositides in model systems. Evidence for specific interaction with phosphatidylinositol-monophosphate and -diphosphate
1 reference
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7 January 2021
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Effect of doxorubicin on the order of the acyl chains of anionic and zwitterionic phospholipids in liquid-crystalline mixed model membranes: absence of drug-induced segregation of lipids into extended domains
1 reference
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7 January 2021
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Role of anionic phospholipids in the interaction of doxorubicin and plasma membrane vesicles: drug binding and structural consequences in bacterial systems
1 reference
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7 January 2021
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Modulatory effects on substrate specificity of independent mutations at the serine939/941 position in predicted transmembrane domain 11 of P-glycoproteins.
1 reference
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Crossref
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7 January 2021
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Transport properties of P-glycoprotein in plasma membrane vesicles from multidrug-resistant Chinese hamster ovary cells
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962148-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
The effects of lipids and detergents on ATPase-active P-glycoprotein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962148-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
Potentiation of anticancer-drug cytotoxicity by multidrug-resistance chemosensitizers involves alterations in membrane fluidity leading to increased membrane permeability.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962148-8
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7 January 2021
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inferred from DOI database lookup
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1 reference
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Crossref
reference URL
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7 January 2021
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inferred from DOI database lookup
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1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962148-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Functional reconstitution of P-glycoprotein reveals an apparent near stoichiometric drug transport to ATP hydrolysis
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962148-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The role of passive transbilayer drug movement in multidrug resistance and its modulation
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962148-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
P-glycoprotein possesses a 1,4-dihydropyridine-selective drug acceptor site which is alloserically coupled to a vinca-alkaloid-selective binding site
1 reference
stated in
Crossref
reference URL
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7 January 2021
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inferred from DOI database lookup
Clinical studies with modulators of multidrug resistance.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962148-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Comparison of the membrane transport of anthracycline derivatives in drug-resistant and drug-sensitive K562 cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962148-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Permeability of lipid bilayer to anthracycline derivatives. Role of the bilayer composition and of the temperature
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962148-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
Comparison of the interaction of doxorubicin, daunorubicin, idarubicin and idarubicinol with large unilamellar vesicles. Circular dichroism study
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962148-8
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7 January 2021
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inferred from DOI database lookup
Absence of cooperativity for MgATP and verapamil effects on the ATPase activity of P-glycoprotein containing membrane vesicles
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962148-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
Influence of cholesterol on gramicidin-induced HII phase formation in phosphatidylcholine model membranes
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962148-8
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7 January 2021
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inferred from DOI database lookup
Saturable P-glycoprotein kinetics assayed by fluorescence studies of drug efflux from suspended human KB8-5 cells.
1 reference
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Crossref
reference URL
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retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Biochemistry of multidrug resistance mediated by the multidrug transporter
1 reference
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Crossref
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7 January 2021
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inferred from DOI database lookup
Isolation and expression of a complementary DNA that confers multidrug resistance
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962148-8
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7 January 2021
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inferred from DOI database lookup
A single amino acid substitution strongly modulates the activity and substrate specificity of the mouse mdr1 and mdr3 drug efflux pumps
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962148-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nonmediated flip-flop of anionic phospholipids and long-chain amphiphiles in the erythrocyte membrane depends on membrane potential
1 reference
stated in
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7 January 2021
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inferred from DOI database lookup
A novel energy dependent mechanism reducing daunorubicin accumulation in acute myeloid leukemia
1 reference
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reference URL
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7 January 2021
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inferred from DOI database lookup
ABC Transporters: From Microorganisms to Man
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962148-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structure of the multidrug resistance P-glycoprotein
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962148-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Is the multidrug transporter a flippase?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962148-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Calcein accumulation as a fluorometric functional assay of the multidrug transporter
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962148-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
ATP-dependent transport of vinblastine in vesicles from human multidrug-resistant cells
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962148-8
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7 January 2021
based on heuristic
inferred from DOI database lookup
Agents which reverse multidrug-resistance are inhibitors of [3H]vinblastine transport by isolated vesicles
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962148-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transepithelial transport of vinblastine by kidney-derived cell lines. Application of a new kinetic model to estimate in situ Km of the pump
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962148-8
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7 January 2021
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inferred from DOI database lookup
Amelioration of adriamycin toxicity through modification of drug-DNA binding properties
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962148-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structurally distinct MDR modulators show specific patterns of reversal against P-glycoproteins bearing unique mutations at serine939/941.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962148-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Clinical drug resistance: the role of factors other than P-glycoprotein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962148-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Anticancer drugs, ionophoric peptides, and steroids as substrates of the yeast multidrug transporter Pdr5p
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962148-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
NMR spin exchange kinetics at equilibrium in membrane transport and enzyme systems.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962148-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Non-Stokesian nature of transverse diffusion within human red cell membranes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962148-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Charles F. Kettering Prize. P-glycoprotein and resistance to anticancer drugs
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962148-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
P-glycoprotein: its role in drug resistance
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962148-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Competitive, non-competitive and cooperative interactions between substrates of P-glycoprotein as measured by its ATPase activity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962148-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interaction of multidrug-resistant Chinese hamster ovary cells with amphiphiles
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962148-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interaction of multidrug-resistant Chinese hamster ovary cells with the peptide ionophore gramicidin D
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962148-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Extended multidrug resistance in haemopoietic cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962148-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The multi-drug resistance reversal agent SR33557 and modulation of vinca alkaloid binding to P-glycoprotein by an allosteric interaction.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962148-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transmembrane potentials and phospholipid flip-flop in excitable membrane vesicles
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962148-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Energy coupling to periplasmic binding protein-dependent transport systems: stoichiometry of ATP hydrolysis during transport in vivo
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962148-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The interaction of adriamycin with cardiolipin in model and rat liver mitochondrial membranes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962148-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Kinetics of daunorubicin transport in Ehrlich ascites tumor cells with different expression of P-glycoprotein.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962148-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Kinetics of Gramicidin Channel Formation in Lipid Bilayers: Transmembrane Monomer Association
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962148-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effects of steroids and verapamil on P-glycoprotein ATPase activity: progesterone, desoxycorticosterone, corticosterone and verapamil are mutually non-exclusive modulators
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962148-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Doxorubicin resistance in P388 leukemia--evidence for reduced drug influx.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962148-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Flip-flop of doxorubicin across erythrocyte and lipid membranes.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962148-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Lower electrical membrane potential and altered pHi homeostasis in multidrug-resistant (MDR) cells: further characterization of a series of MDR cell lines expressing different levels of P-glycoprotein.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962148-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Amplification of specific DNA sequences correlates with multi-drug resistance in Chinese hamster cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962148-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Asymmetric exchange of vesicle phospholipids catalyzed by the phosphatidylcholine exchange protein. Measurement of inside-outside transitions
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962148-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interaction between daunorubicin and chromatin from Ehrlich ascites tumor cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962148-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Specific drug binding by purified lipid-reconstituted P-glycoprotein: dependence on the lipid composition
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962148-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
P-glycoprotein-mediated transcellular transport of MDR-reversing agents
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962148-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962148-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Increased plasma membrane traffic in daunorubicin resistant P388 leukaemic cells. Effect of daunorubicin and verapamil
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962148-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
P-glycoprotein shows strong catalytic cooperativity between the two nucleotide sites.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962148-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of initial vinblastine influx by P-glycoprotein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962148-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutually co-operative interactions between modulators of P-glycoprotein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962148-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Reconstitution of Drug Transport by Purified P-glycoprotein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962148-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Positively cooperative sites for drug transport by P-glycoprotein with distinct drug specificities
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962148-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Characterization and functional reconstitution of the multidrug transporter.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962148-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Modulation and prevention of multidrug resistance by inhibitors of P-glycoprotein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962148-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cell biological mechanisms of multidrug resistance in tumors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962148-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Markedly altered membrane transport and intracellular binding of vincristine in multidrug-resistant Chinese hamster cells selected for resistance to vinca alkaloids.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962148-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transport studies of doxorubicin in model membranes indicate a difference in passive diffusion across and binding at the outer and inner leaflets of the plasma membrane.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962148-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
P-glycoprotein drug efflux pump involved in the mechanisms of intrinsic drug resistance in various colon cancer cell lines. Evidence for a saturation of active daunorubicin transport
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962148-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Kinetics of daunorubicin transport by P-glycoprotein of intact cancer cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962148-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Kinetics of the multidrug transporter (P-glycoprotein) and its reversal
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962148-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Anthracycline incorporation in human lymphocytes. Kinetics of uptake and nuclear concentration.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962148-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962148-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Amine and carboxylate spin probe permeability in red cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962148-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Intracellular Measurements of Ion Activities
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962148-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The mdrl gene, responsible for multidrug-resistance, codes for P-glycoprotein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962148-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
How does P-glycoprotein recognize its substrates?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962148-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Characterization of the ATPase activity of purified Chinese hamster P-glycoprotein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962148-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutations in either nucleotide-binding site of P-glycoprotein (Mdr3) prevent vanadate trapping of nucleotide at both sites.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962148-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Both P-glycoprotein Nucleotide-binding Sites Are Catalytically Active
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962148-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effects of lipids on ATPase activity of purified Chinese hamster P-glycoprotein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962148-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The gramicidin A transmembrane channel: a proposed pi(L,D) helix
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962148-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Gramicidin A Transmembrane Channel: Characteristics of Head-to-Head Dimerized π (L,D) Helices
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962148-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The role of drug-lipid interactions in the biological activity of modulators of multi-drug resistance.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962148-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Permeability of small nonelectrolytes through lipid bilayer membranes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962148-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The effect of ion channel blockers, immunosuppressive agents, and other drugs on the activity of the multi-drug transporter
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962148-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Exchange and flip-flop of dimyristoylphosphatidylcholine in liquid-crystalline, gel, and two-component, two-phase large unilamellar vesicles
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962148-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transbilayer and interbilayer phospholipid exchange in dimyristoylphosphatidylcholine/dimyristoylphosphatidylethanolamine large unilamellar vesicles
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962148-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Reversal of multidrug resistance by surfactants
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962148-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The relationship between permeant size and permeability in lipid bilayer membranes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962148-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The simulation of the urea cycle: correlation of effects due to inborn errors in the catalytic properties of the enzymes with clinical-biochemical observations
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962148-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Distantly related sequences in the alpha- and beta-subunits of ATP synthase, myosin, kinases and other ATP-requiring enzymes and a common nucleotide binding fold
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2808%2962148-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0074-7696(08)62148-8
1 reference
stated in
Europe PubMed Central
PubMed ID
10331240
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10331240%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 December 2019
PubMed ID
10331240
1 reference
stated in
Europe PubMed Central
PubMed ID
10331240
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10331240%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 December 2019
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