(Q33637455)

28 July 2017

title

Androgen receptor counteracts Doxorubicin-induced cardiotoxicity in male mice (English)

1 reference

28 July 2017

Yasumasa Ikeda

1

1 reference

28 July 2017

Ken-ichi Aihara

2

1 reference

28 July 2017

Masashi Akaike

3

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28 July 2017

Takashi Sato

4

1 reference

28 July 2017

Kazue Ishikawa

5

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28 July 2017

Takayuki Ise

6

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28 July 2017

Shusuke Yagi

7

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28 July 2017

Takashi Iwase

8

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28 July 2017

Yuka Ueda

9

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28 July 2017

Sumiko Yoshida

10

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28 July 2017

Hiroyuki Azuma

11

1 reference

28 July 2017

Kenneth Walsh

12

1 reference

28 July 2017

Toshiaki Tamaki

13

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28 July 2017

Shigeaki Kato

14

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28 July 2017

Toshio Matsumoto

15

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28 July 2017

publication date

25 May 2010

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28 July 2017

published in

Molecular Endocrinology

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28 July 2017

volume

24

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28 July 2017

issue

7

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28 July 2017

page(s)

1338-1348

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Cardiac-specific deletion of LKB1 leads to hypertrophy and dysfunction

28 July 2017

cites work

1 reference

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Heat shock protein 20 interacting with phosphorylated Akt reduces doxorubicin-triggered oxidative stress and cardiotoxicity

21 June 2018

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Strain-dependent embryonic lethality and exaggerated vascular remodeling in heparin cofactor II-deficient mice

21 June 2018

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Premature ovarian failure in androgen receptor-deficient mice

21 June 2018

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Vascular smooth muscle cell proliferation is dependent upon upregulation of mitochondrial transcription factor A (mtTFA) expression in injured rat carotid artery.

21 June 2018

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Subfertility and defective folliculogenesis in female mice lacking androgen receptor

21 June 2018

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Regulation of cell size and contractile function by AKT in cardiomyocytes.

21 June 2018

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Brain masculinization requires androgen receptor function

21 June 2018

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Androgen receptor functions from reverse genetic models

21 June 2018

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Suppressive function of androgen receptor in bone resorption

21 June 2018

1 reference

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Akt and PI 3-kinase signaling in cardiomyocyte hypertrophy and survival

21 June 2018

1 reference

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Mitochondrial reactive oxygen species in cell death signaling

21 June 2018

1 reference

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Animal mitochondrial biogenesis and function: a regulatory cross-talk between two genomes

21 June 2018

1 reference

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Glycoprotein 130 regulates cardiac myocyte survival in doxorubicin-induced apoptosis through phosphatidylinositol 3-kinase/Akt phosphorylation and Bcl-xL/caspase-3 interaction

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5417461

The regulation and activities of the multifunctional serine/threonine kinase Akt/PKB.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5417461

Apoptosis in heart failure: release of cytochrome c from mitochondria and activation of caspase-3 in human cardiomyopathy

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5417461

Mitochondrial transcription factor A is necessary for mtDNA maintenance and embryogenesis in mice

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5417461

Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3,4-bisphosphate

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5417461

The protective role of manganese superoxide dismutase against adriamycin-induced acute cardiac toxicity in transgenic mice

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5417461

Mitochondrial DNA polymerase gamma is expressed and translated in the absence of mitochondrial DNA maintenance and replication

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5417461

Evidence of cardiocyte apoptosis in myocardium of dogs with chronic heart failure.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5417461

Low levels of mitochondrial transcription factor A in mitochondrial DNA depletion

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5417461

Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5417461

A clinicopathologic analysis of adriamycin cardiotoxicity

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5417461

Subcellular effects of adriamycin in the heart: a concise review

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5417461

Doxorubicin cardiotoxicity: analysis of prevailing hypotheses

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5417461

Early anthracycline cardiotoxicity

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5417461

Anthracycline cardiomyopathy monitored by morphologic changes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5417461

Risk factors for doxorubicin-induced congestive heart failure

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5417461

Androgen-androgen receptor system protects against angiotensin II-induced vascular remodeling

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5417461

Tissue-specific mtDNA lesions and radical-associated mitochondrial dysfunction in human hearts exposed to doxorubicin

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5417461

Nontranscriptional regulation of cardiac repolarization currents by testosterone

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5417461

Disruption of coordinated cardiac hypertrophy and angiogenesis contributes to the transition to heart failure

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5417461

Androgen receptor null male mice develop late-onset obesity caused by decreased energy expenditure and lipolytic activity but show normal insulin sensitivity with high adiponectin secretion.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5417461

Oxidative damage precedes nitrative damage in adriamycin-induced cardiac mitochondrial injury

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5417461

Modulation of doxorubicin-induced cardiac dysfunction in toll-like receptor-2-knockout mice

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5417461

Detection of intracellular superoxide formation in endothelial cells and intact tissues using dihydroethidium and an HPLC-based assay

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5417461

Disruption of nuclear vitamin D receptor gene causes enhanced thrombogenicity in mice

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5417461

Heparin cofactor II is a novel protective factor against carotid atherosclerosis in elderly individuals

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5417461

RETRACTED: Activation of phosphatidylinositol 3-kinase/Akt pathway by androgen through interaction of p85alpha, androgen receptor, and Src.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5417461

Depressed mitochondrial transcription factors and oxidative capacity in rat failing cardiac and skeletal muscles.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5417461

Carvedilol protects against doxorubicin-induced mitochondrial cardiomyopathy

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5417461

Late onset of obesity in male androgen receptor-deficient (AR KO) mice

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5417461

Doxorubicin treatment in vivo causes cytochrome C release and cardiomyocyte apoptosis, as well as increased mitochondrial efficiency, superoxide dismutase activity, and Bcl-2:Bax ratio.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5417461

Mitochondrial DNA damage and dysfunction associated with oxidative stress in failing hearts after myocardial infarction

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5417461

Androgen receptors mediate hypertrophy in cardiac myocytes

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5417461

Effect of anthracycline antibiotics on oxygen radical formation in rat heart

30 October 2018

1 reference

12 December 2020

Elevated myocardial Akt signaling ameliorates doxorubicin-induced congestive heart failure and promotes heart growth

1 reference

12 December 2020

Adriamycin-induced free radical formation in the perfused rat heart: implications for cardiotoxicity

1 reference

12 December 2020

Apoptosis in the heart

1 reference

12 December 2020

Over-expression of heat shock protein 27 attenuates doxorubicin-induced cardiac dysfunction in mice

1 reference

12 December 2020

Apoptosis in human acute myocardial infarction

1 reference

12 December 2020

Oxygen radical injury in the presence of desferal, a specific iron-chelating agent

1 reference

12 December 2020

Mechanisms of beneficial effects of probucol in adriamycin cardiomyopathy

1 reference

12 December 2020

Signaling pathways in reactive oxygen species-induced cardiomyocyte apoptosis

1 reference

12 December 2020

Androgen receptor gene knockout male mice exhibit impaired cardiac growth and exacerbation of angiotensin II-induced cardiac fibrosis

1 reference

12 December 2020

Doxorubicin-induced cardiomyopathy

1 reference

12 December 2020

Regulation of bcl-2 family proteins during development and in response to oxidative stress in cardiac myocytes: association with changes in mitochondrial membrane potential

1 reference

12 December 2020

Spin-trapping and direct electron spin resonance investigations of the redox metabolism of quinone anticancer drugs

1 reference

12 December 2020

Apoptosis in myocytes in end-stage heart failure

1 reference

12 December 2020

Identifiers

DOI

10.1210/ME.2009-0402

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28 July 2017

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28 July 2017

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