(Q33639481)

28 July 2017

1 reference

title

Targeting Adenosine Receptors for the Treatment of Cardiac Fibrosis (English)

1 reference

28 July 2017

Elizabeth A Vecchio

1

1 reference

28 July 2017

Paul J White

series ordinal

2

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28 July 2017

Lauren T May

series ordinal

3

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28 July 2017

publication date

5 May 2017

1 reference

Frontiers in Pharmacology

28 July 2017

published in

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28 July 2017

volume

8

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28 July 2017

page(s)

243

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Adenosine A2B Receptor: From Cell Biology to Human Diseases

28 July 2017

cites work

1 reference

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The hybrid molecule, VCP746, is a potent adenosine A2B receptor agonist that stimulates anti-fibrotic signalling

14 July 2018

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Genetic Abrogation of Adenosine A3 Receptor Prevents Uninephrectomy and High Salt-Induced Hypertension.

14 July 2018

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VCP746, a novel A1 adenosine receptor biased agonist, reduces hypertrophy in a rat neonatal cardiac myocyte model.

14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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Adenosine A1 receptor activation attenuates cardiac hypertrophy and fibrosis in response to α1 -adrenoceptor stimulation in vivo.

14 July 2018

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Purinergic signaling in scarring

14 July 2018

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Adenosine receptor expression in the development of renal fibrosis following ischemic injury

14 July 2018

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Cardiac myocyte-secreted cAMP exerts paracrine action via adenosine receptor activation.

14 July 2018

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The role of adenosine receptors A2A and A2B signaling in renal fibrosis

14 July 2018

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14 July 2018

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Adenosine 2A receptor promotes collagen production by human fibroblasts via pathways involving cyclic AMP and AKT but independent of Smad2/3.

14 July 2018

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Increase in cellular cyclic AMP concentrations reverses the profibrogenic phenotype of cardiac myofibroblasts: a novel therapeutic approach for cardiac fibrosis

14 July 2018

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14 July 2018

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14 July 2018

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Chronic therapy with a partial adenosine A1-receptor agonist improves left ventricular function and remodeling in dogs with advanced heart failure

14 July 2018

1 reference

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Adenosine signaling during acute and chronic disease states

14 July 2018

1 reference

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Fibrosis and heart failure

14 July 2018

1 reference

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Adora2b adenosine receptor signaling protects during acute kidney injury via inhibition of neutrophil-dependent TNF-α release

14 July 2018

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14 July 2018

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Cardioprotection of controlled and cardiac-specific over-expression of A(2A)-adenosine receptor in the pressure overload

14 July 2018

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14 July 2018

1 reference

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Adenosine receptor-mediated cardioprotection: are all 4 subtypes required or redundant?

14 July 2018

1 reference

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Distinct roles for the A2B adenosine receptor in acute and chronic stages of bleomycin-induced lung injury.

14 July 2018

1 reference

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A(2b) adenosine receptors can change their spots

14 July 2018

1 reference

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Stimulation of adenosine A(2B) receptors induces interleukin-6 secretion in cardiac fibroblasts via the PKC-delta-P38 signalling pathway.

14 July 2018

1 reference

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Cardiac fibroblast: the renaissance cell

14 July 2018

1 reference

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14 July 2018

Adenosine in fibrosis.

1 reference

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Cardiac fibroblasts: at the heart of myocardial remodeling

14 July 2018

1 reference

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Adenosine signaling and the regulation of chronic lung disease

14 July 2018

1 reference

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Regulation of cardiac fibroblast collagen synthesis by adenosine: roles for Epac and PI3K.

14 July 2018

1 reference

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Adenosine receptors and second messenger signaling pathways in rat cardiac fibroblasts

14 July 2018

1 reference

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The adenosine a2b receptor: its role in inflammation

14 July 2018

1 reference

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Adenosine A3 receptor deficiency exerts unanticipated protective effects on the pressure-overloaded left ventricle

14 July 2018

1 reference

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Adenosine receptors: therapeutic aspects for inflammatory and immune diseases

14 July 2018

1 reference

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Ecto-5'-nucleotidase deficiency exacerbates pressure-overload-induced left ventricular hypertrophy and dysfunction.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5418340

The adenosine A1 receptor antagonist SLV320 reduces myocardial fibrosis in rats with 5/6 nephrectomy without affecting blood pressure

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5418340

Adenosinergic cardioprotection: multiple receptors, multiple pathways

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5418340

Role of adenosine as adjunctive therapy in acute myocardial infarction

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5418340

TGFbeta, cardiac fibroblasts, and the fibrotic response

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5418340

Role of A2B adenosine receptor signaling in adenosine-dependent pulmonary inflammation and injury

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5418340

Adenosine A(2A) receptors play a role in the pathogenesis of hepatic cirrhosis

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5418340

Fibrosis as a therapeutic target post-myocardial infarction.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5418340

Inhibition of cardiac myofibroblast formation and collagen synthesis by activation and overexpression of adenylyl cyclase

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5418340

Functional effects of enhancing or silencing adenosine A2b receptors in cardiac fibroblasts

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5418340

Cardiac overexpression of A1-adenosine receptor protects intact mice against myocardial infarction

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5418340

International Union of Pharmacology. XXV. Nomenclature and classification of adenosine receptors

14 July 2018

1 reference

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Molecular approach to adenosine receptors: receptor-mediated mechanisms of tissue protection

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5418340

A(2b) receptors mediate the antimitogenic effects of adenosine in cardiac fibroblasts

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5418340

Selective regulation of endogenous G protein-coupled receptors by arrestins in HEK293 cells

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5418340

Angiotensin II, adhesion, and cardiac fibrosis

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5418340

Characterization of human A(2B) adenosine receptors: radioligand binding, western blotting, and coupling to G(q) in human embryonic kidney 293 cells and HMC-1 mast cells

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5418340

Adenosine inhibits collagen and protein synthesis in cardiac fibroblasts: role of A2B receptors

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5418340

14 July 2018

Adenosine A2B receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5418340

Adenosine and adenosine receptors in the cardiovascular system: biochemistry, physiology, and pharmacology

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5418340

Impact of adenosine receptor signaling and metabolism on pathophysiology in patients with chronic heart failure

14 July 2018

1 reference

https://api.crossref.org/works/10.3389%2FFPHAR.2017.00243

Fibroblast network in rabbit sinoatrial node: structural and functional identification of homogeneous and heterogeneous cell coupling.

21 January 2018

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Adenosine A2A receptors in diffuse dermal fibrosis: pathogenic role in human dermal fibroblasts and in a murine model of scleroderma.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFPHAR.2017.00243

Endogenous cyclic AMP-adenosine pathway regulates cardiac fibroblast growth

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFPHAR.2017.00243

A randomized, double-blinded, placebo-controlled, dose-ranging study measuring the effect of an adenosine agonist on infarct size reduction in patients undergoing primary percutaneous transluminal coronary angioplasty: the ADMIRE (AmP579 Delivery fo

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFPHAR.2017.00243

Activation of adenosine A1 receptor attenuates cardiac hypertrophy and prevents heart failure in murine left ventricular pressure-overload model

21 January 2018

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https://api.crossref.org/works/10.3389%2FFPHAR.2017.00243

Metalloproteinase inhibitor counters high-energy phosphate depletion and AMP deaminase activity enhancing ventricular diastolic compliance in subacute heart failure

21 January 2018

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https://api.crossref.org/works/10.3389%2FFPHAR.2017.00243

A randomized, double-blinded, placebo-controlled multicenter trial of adenosine as an adjunct to reperfusion in the treatment of acute myocardial infarction (AMISTAD-II).

21 January 2018

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https://api.crossref.org/works/10.3389%2FFPHAR.2017.00243

Enhanced airway inflammation and remodeling in adenosine deaminase-deficient mice lacking the A2B adenosine receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFPHAR.2017.00243

GS-6201, a selective blocker of the A2B adenosine receptor, attenuates cardiac remodeling after acute myocardial infarction in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFPHAR.2017.00243

Blockade of A2B adenosine receptor reduces left ventricular dysfunction and ventricular arrhythmias 1 week after myocardial infarction in the rat model

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFPHAR.2017.00243

Regulated Overexpression of the A 1 -Adenosine Receptor in Mice Results in Adverse but Reversible Changes in Cardiac Morphology and Function

21 January 2018

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12 December 2020

Adenosine receptor subtypes in the heart: therapeutic opportunities and challenges

1 reference

12 December 2020

Exogenous and endogenous adenosine inhibits fetal calf serum-induced growth of rat cardiac fibroblasts: role of A2B receptors

1 reference

12 December 2020

Long-term stimulation of adenosine A2b receptors begun after myocardial infarction prevents cardiac remodeling in rats

1 reference

12 December 2020

Stimulation of collagen production by transforming growth factor-beta1 during differentiation of cardiac fibroblasts to myofibroblasts

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12 December 2020

Identifiers

DOI

10.3389/FPHAR.2017.00243

1 reference

28 July 2017

1 reference

28 July 2017

1 reference