(Q33641923)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28281872%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

title

Novel anti-Sialyl-Tn monoclonal antibodies and antibody-drug conjugates demonstrate tumor specificity and anti-tumor activity (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28281872%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

1 reference

1

1 reference

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5 April 2020

author name string

Ana Paula Galvao da Silva

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28281872%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

David A Eavarone

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28281872%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

Darius Ghaderi

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28281872%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

Mai Zhang

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28281872%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

Dane Brady

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28281872%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

Joan Wicks

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28281872%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

Julie DeSander

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28281872%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

Jeff Behrens

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28281872%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

Bo R Rueda

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28281872%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

publication date

22 February 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28281872%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

published in

Monoclonal Antibodies

1 reference

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5 April 2020

volume

9

1 reference

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5 April 2020

issue

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28281872%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

page(s)

615-627

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28281872%20AND%20SRC:MED&resulttype=core&format=json

Effective antitumor therapy based on a novel antibody-drug conjugate targeting the Tn carbohydrate antigen

5 April 2020

cites work

1 reference

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Engineered CAR T Cells Targeting the Cancer-Associated Tn-Glycoform of the Membrane Mucin MUC1 Control Adenocarcinoma

21 June 2018

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Intracellular Released Payload Influences Potency and Bystander-Killing Effects of Antibody-Drug Conjugates in Preclinical Models

21 June 2018

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Role of antibodies in diagnosis and treatment of ovarian cancer: Basic approach and clinical status.

21 June 2018

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21 June 2018

Cancer statistics, 2016

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Antibody-drug conjugates--an emerging class of cancer treatment

21 June 2018

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Strategies and Advancement in Antibody-Drug Conjugate Optimization for Targeted Cancer Therapeutics

21 June 2018

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Phase 2 study of frontline brentuximab vedotin monotherapy in Hodgkin lymphoma patients aged 60 years and older.

21 June 2018

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Challenges in Antibody Development against Tn and Sialyl-Tn Antigens

21 June 2018

1 reference

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Significant Impact of Immunogen Design on the Diversity of Antibodies Generated by Carbohydrate-Based Anticancer Vaccine

21 June 2018

1 reference

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A novel humanized anti-HER2 antibody conjugated with MMAE exerts potent anti-tumor activity

21 June 2018

1 reference

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Glycosyltransferases as Markers for Early Tumorigenesis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5419082

COSMC knockdown mediated aberrant O-glycosylation promotes oncogenic properties in pancreatic cancer.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5419082

The Breast Cancer-Associated Glycoforms of MUC1, MUC1-Tn and sialyl-Tn, Are Expressed in COSMC Wild-Type Cells and Bind the C-Type Lectin MGL.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5419082

Trial watch: Tumor-targeting monoclonal antibodies for oncological indications

21 June 2018

1 reference

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Protein glycosylation in cancer

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5419082

Sialyl-tn in cancer: (how) did we miss the target?

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5419082

Sialyl Tn-expressing bladder cancer cells induce a tolerogenic phenotype in innate and adaptive immune cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5419082

Altered tumor-cell glycosylation promotes metastasis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5419082

Cell surface protein glycosylation in cancer

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5419082

Antibody-drug conjugates: current status and future directions

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5419082

Aiming at the sweet side of cancer: aberrant glycosylation as possible target for personalized-medicine

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5419082

Survival Advantage in Patients with Metastatic Breast Cancer Receiving Endocrine Therapy plus Sialyl Tn-KLH Vaccine: Post Hoc Analysis of a Large Randomized Trial

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5419082

Tn and sialyl-Tn antigens, aberrant O-glycomics as human disease markers

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5419082

CpG ODN and ISCOMATRIX adjuvant: a synergistic adjuvant combination inducing strong T-Cell IFN-γ responses

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5419082

Antibody therapy of cancer

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5419082

Enhancement of metastatic ability by ectopic expression of ST6GalNAcI on a gastric cancer cell line in a mouse model.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5419082

Phase III multicenter clinical trial of the sialyl-TN (STn)-keyhole limpet hemocyanin (KLH) vaccine for metastatic breast cancer

21 June 2018

1 reference

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Human xeno-autoantibodies against a non-human sialic acid serve as novel serum biomarkers and immunotherapeutics in cancer.

21 June 2018

1 reference

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The safety and side effects of monoclonal antibodies

21 June 2018

1 reference

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Sialyl-Tn vaccine induces antibody-mediated tumour protection in a relevant murine model

21 June 2018

1 reference

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Monoclonal antibodies in cancer therapy: 25 years of progress

21 June 2018

1 reference

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One-pot three-enzyme chemoenzymatic approach to the synthesis of sialosides containing natural and non-natural functionalities

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5419082

Biological significance of cancer-associated sialyl-Tn antigen: modulation of malignant phenotype in gastric carcinoma cells.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5419082

Stable expression of sialyl-Tn antigen in T47-D cells induces a decrease of cell adhesion and an increase of cell migration.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5419082

Expression of sialyl-Tn antigen in breast cancer cells transfected with the human CMP-Neu5Ac: GalNAc alpha2,6-sialyltransferase (ST6GalNac I) cDNA.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5419082

Phase II study of interferon-enhanced 131I-labeled high affinity CC49 monoclonal antibody therapy in patients with metastatic prostate cancer.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5419082

Treatment of metastatic prostate carcinoma with radiolabeled antibody CC49.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5419082

Immune sera and monoclonal antibodies define two configurations for the sialyl Tn tumor antigen.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5419082

Tumor targeting with monoclonal antibody B72.3.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5419082

Preparation and characterization of monoclonal antibodies directed to the tumor-associated O-linked sialosyl-2----6 alpha-N-acetylgalactosaminyl (sialosyl-Tn) epitope.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5419082

Characterization of the shed form of the human tumor-associated glycoprotein (TAG-72) from serous effusions of patients with different types of carcinomas

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5419082

Tumor targeting with monoclonal antibody B72.3: experimental and clinical results

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5419082

Radiolabeled antibody imaging in the management of colorectal cancer. Results of a multicenter clinical study

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5419082

Armed antibodies targeting the mucin repeats of the ovarian cancer antigen, MUC16, are highly efficacious in animal tumor models

21 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1080%2F19420862.2017.1290752

Changes in the profile of simple mucin-type O-glycans and polypeptide GalNAc-transferases in human testis and testicular neoplasms are associated with germ cell maturation and tumour differentiation.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1080%2F19420862.2017.1290752

Analysis of the fine specificity of Tn-binding proteins using synthetic glycopeptide epitopes and a biosensor based on surface plasmon resonance spectroscopy

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1080%2F19420862.2017.1290752

Thomsen-Friedenreich-related carbohydrate antigens in normal adult human tissues: a systematic and comparative study

21 January 2018

1 reference

12 December 2020

Different levels of sialyl-Tn antigen expressed on MUC16 in patients with endometriosis and ovarian cancer

1 reference

12 December 2020

Highly sensitive determination of N-acetyl- and N-glycolylneuraminic acids in human serum and urine and rat serum by reversed-phase liquid chromatography with fluorescence detection

1 reference

12 December 2020

The discovery and development of brentuximab vedotin for use in relapsed Hodgkin lymphoma and systemic anaplastic large cell lymphoma

1 reference

12 December 2020

Specificities of anti-sialyl-Tn and anti-Tn monoclonal antibodies generated using novel clustered synthetic glycopeptide epitopes

1 reference

12 December 2020

A detailed study of the periodate oxidation of sialic acids in glycoproteins

1 reference

12 December 2020

10.1080/19420862.2017.1290752

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28281872%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28281872%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

PubMed publication ID

28281872

1 reference